Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sichong Han"'
Autor:
Yunxia Ge, Xiaodan Yan, Yiguang Jin, Xinyu Yang, Xiang Yu, Liqing Zhou, Sichong Han, Qipeng Yuan, Ming Yang
Publikováno v:
PLoS Genetics, Vol 11, Iss 12, p e1005726 (2015)
Accumulated evidence demonstrated that long non-coding RNAs (lncRNAs) play a pivotal role in tumorigenesis. However, it is still largely unknown how these lncRNAs were regulated by small ncRNAs, such as microRNAs (miRNAs), at the post-transcriptional
Externí odkaz:
https://doaj.org/article/80780a2e28904f56aec447f7b62d8655
Publikováno v:
Cell Death and Disease, Vol 11, Iss 8, Pp 1-13 (2020)
Cell Death & Disease
Cell Death & Disease
Esophageal cancer is one of the most common cancer with limited therapeutic strategies, thus it is important to develop more effective strategies to against it. Sulforaphene (SFE), an isothiocyanate isolated from radish seeds, was proved to inhibit e
Autor:
Huiyu Liu, Junjie Ma, Li Cheng, Xueting Pan, Qipeng Yuan, Heyun Shen, Shunhao Wang, Sichong Han, Hongyu Wang, Fengrong Zhang, Shuang Liu
Publikováno v:
Angewandte Chemie. 131:7810-7814
Enzymes have been used to direct the conversion of prodrugs in cancer therapy. However, non-specific distribution of endogenous enzymes seriously hinders their bioapplications. Herein, we developed a near-infrared-triggered locoregional chemo-phototh
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 1
International Journal of Molecular Sciences, Vol 22, Iss 60, p 60 (2021)
Volume 22
Issue 1
International Journal of Molecular Sciences, Vol 22, Iss 60, p 60 (2021)
Understanding the mechanism by which sulforaphene (SFE) affects esophageal squamous cell carcinoma (ESCC) contributes to the application of this isothiocyanate as a chemotherapeutic agent. Thus, we attempted to investigate SFE regulation of ESCC char
Publikováno v:
Biochemical Pharmacology. 188:114539
The antitumor properties of cruciferous vegetables are mainly due to their high content of isothiocyanates, and sulforaphane (SFA) is the most well-known compound. The aim of this study was to determine the mechanism of SFA inhibiting gastric cancer
Autor:
Ming Yang, Hongwei Chen, Xinyu Wang, Zhiqiong Wang, Sichong Han, Yanli Ren, Wenting Pan, Xiangyu Xiong, Liqing Zhou, Changchun Zhou, Qipeng Yuan
Publikováno v:
FEBS Letters. 589:3989-3997
5S rRNA plays an important part in ribosome biology and is over-expression in multiple cancers. In this study, we found that 5S rRNA is a direct target of miR-150 and miR-383 in esophageal squamous cell carcinoma (ESCC). Overexpression of miR-150 and
Autor:
Ming Yang, Qipeng Yuan, Wenting Pan, Liqing Zhou, Xiangyu Xiong, Xinyu Yang, Yanli Ren, Yunxia Ge, Xinyu Wang, Sichong Han
Publikováno v:
FEBS Letters. 589:4079-4087
treRNA is a long non-coding RNA (lncRNA) involved in cancer progression. In this study, we show that miR-190a can silence treRNA post-transcriptionally. Suppression of treRNA by miR-190a led to significant changes of mesenchymal-epithelial transition
Autor:
Hongwei Chen, Fei Ma, Xinyu Yang, Changchun Zhou, Xue Liang, Sichong Han, Yanli Ren, Ming Yang, Feng Gao, Liqing Zhou, Wenting Pan, Xiangyu Xiong
Publikováno v:
Tumor Biology. 37:1693-1698
As a well-known oncogene, B cell lymphoma-2 (BCL-2) can promote cancer cell survival through preventing their apoptosis. Several functional BCL-2 single nucleotide polymorphisms (SNPs), such as rs2279115, rs1801018, and rs1564483, have been identifie
Autor:
Liqing Zhou, Yunxia Ge, Xinyu Wang, Changchun Zhou, Zhiqiong Wang, Xiaohu Tang, Meng Li, Sichong Han, Qipeng Yuan, Ming Yang
Publikováno v:
Journal of Biological Chemistry. 290:3925-3935
MALAT1, a highly conserved long noncoding RNA, is deregulated in several types of cancers. However, its role in esophageal squamous cell carcinoma (ESCC) and its posttranscriptional regulation remain poorly understood. In this study we provide first
Autor:
Ming Yang, Yunxia Ge, Wenting Pan, Yi-Dong Chen, Jinyu Wei, Tao Jiang, Xiaoguang Qiu, Chao Lu, Sichong Han
Publikováno v:
Journal of Neuro-Oncology. 120:11-17
As a crucial homologous recombination repair gene, RAD52 participates in maintenance of genomic stability and prevention of tumorigenesis. Although several cancer susceptibility RAD52 single nucleotide polymorphisms (SNPs) have been identified previo