Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Sicheng Yan"'
Autor:
Sicheng Yan, Yuxuan He, Yuehong Zhu, Wangfang Ye, Yan Chen, Cong Zhu, Fuyuan Zhan, Zhihong Ma
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Gastrointestinal cancers account for approximately one-third of the total global cancer incidence and mortality with a poor prognosis. It is one of the leading causes of cancer-related deaths worldwide. Most of these diseases lack effective treatment
Externí odkaz:
https://doaj.org/article/1e32a4f388124af1b87f652d7011a5f2
Autor:
Liping Chen, Chunhui Huang, Jieyi Shentu, Minjun Wang, Sicheng Yan, Fei Zhou, Zaijun Zhang, Chuang Wang, Yifan Han, Qinwen Wang, Wei Cui
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Indirubins are natural occurring alkaloids extracted from indigo dye-containing plants. Indirubins could inhibit various kinases, and might be used to treat chronic myelocytic leukemia, cancer and neurodegenerative disorders. 7-bromoindirubin-3-oxime
Externí odkaz:
https://doaj.org/article/317fe1c2793e4653bfc36bab2c38ff0d
Autor:
Qingmei Sun, Fufeng Liu, Jingcheng Sang, Miaoman Lin, Jiale Ma, Xiao Xiao, Sicheng Yan, C. Benjamin Naman, Ning Wang, Shan He, Xiaojun Yan, Wei Cui, Hongze Liang
Publikováno v:
Marine Drugs, Vol 17, Iss 2, p 121 (2019)
β-Amyloid (Aβ) is regarded as an important pathogenic target for Alzheimer’s disease (AD), the most prevalent neurodegenerative disease. Aβ can assemble into oligomers and fibrils, and produce neurotoxicity. Therefore, Aβ aggregation inhibitors
Externí odkaz:
https://doaj.org/article/d1ce0ae5b1c34fb58bcbe943bb5960b4
Autor:
Jiaying Zhao, Fufeng Liu, Chunhui Huang, Jieyi Shentu, Minjun Wang, Chenkai Sun, Liping Chen, Sicheng Yan, Fang Fang, Yuanyuan Wang, Shujun Xu, C. Benjamin Naman, Qinwen Wang, Shan He, Wei Cui
Publikováno v:
Molecules, Vol 22, Iss 10, p 1651 (2017)
The oligomer of β-amyloid (Aβ) is considered the main neurotoxin in Alzheimer’s disease (AD). Therefore, the inhibition of the formation of Aβ oligomer could be a target for AD therapy. In this study, with the help of the dot blotting assay and
Externí odkaz:
https://doaj.org/article/6b2e7b47870c41f494cee1b7c2fbda05
Autor:
Sicheng Yan
Publikováno v:
Proceedings of the 2022 2nd International Conference on Modern Educational Technology and Social Sciences (ICMETSS 2022) ISBN: 9782494069442
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::789c26c78324814e8ce32ccfaf15b5c2
https://doi.org/10.2991/978-2-494069-45-9_27
https://doi.org/10.2991/978-2-494069-45-9_27
Autor:
Wei Cui, Sicheng Yan, C. Benjamin Naman, Zhuoying Wu, Jin Lingli, Xiaojun Yan, Bojun Chen, Hongze Liang, Qiyao Wang, Lingling Zhao, Jinrong Zhang, Mengxiang Yang, Panpan Zhang, Shan He, Yanfei Xie
Publikováno v:
Journal of Agricultural and Food Chemistry. 69:9764-9777
The marine natural product fucoxanthin has been reported previously to produce anti-Alzheimer's disease (AD) neuroprotective effects in vitro and in vivo. Fucoxanthin was also demonstrated to be safe in preclinical and small population clinical studi
Autor:
Yifan Han, Wei Cui, Yiying Zhou, Yanfei Xie, Karl Wah Keung Tsim, Xinmei Gu, Hui Zhang, Haibo Jin, Sicheng Yan, Marvin Mak, Dongsheng Zhou, Paul R. Carlier, Zhenquan Xuan, Shengquan Hu
Publikováno v:
ACS Chemical Neuroscience. 12:2462-2477
Alzheimer's disease (AD) is a neurodegenerative disorder with multiple pathological features. Therefore, a multitarget-directed ligands (MTDLs) strategy has been developed to treat AD. We have previously designed and synthesized dimeric tacrine(10)-h
Autor:
Jianfang Liu, Ting Liu, Rongrong Zhang, Sicheng Yang, Yaoyun Zhang, Chenglingzi Yi, Shuai Peng, Qing Yang
Publikováno v:
ACS Omega, Vol 9, Iss 19, Pp 21333-21345 (2024)
Externí odkaz:
https://doaj.org/article/3d7ef7392469464cb065b0f6ada392c5
Autor:
Mengxiang Yang, Jinrong Zhang, Wei Cui, C. Benjamin Naman, Qiyao Wang, Xiaojun Yan, Sicheng Yan, Dongsheng Zhou, Shan He, Zhenquan Xuan
Publikováno v:
Nutritional neuroscience. 25(10)
Fucoxanthin, one of the most abundant carotenoids from edible brown seaweeds, for years has been used as a bioactive dietary supplement and functional food ingredient. Recently, fucoxanthin was reported to penetrate the blood-brain barrier, and was s
Autor:
Dongsheng Zhou, Yiying Zhou, Zhenquan Xuan, Paul R. Carlier, Haibo Jin, Wei Cui, Sicheng Yan, Shengquan Hu, Karl Wah Keung Tsim, Yifan Han, Yanfei Xie, Hui Zhang, Xingmei Gu, Marvin Shing-Hung Mak
Background Alzheimer’s disease (AD) is a neurodegenerative disorder with multiple pathological features. Therefore, multi-target-directed ligands (MTDLs) strategy has been developed to combat this disease. We have previously designed and synthesize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b114556c414e3d1cd101a72917a5bb6f
https://doi.org/10.21203/rs.3.rs-236543/v1
https://doi.org/10.21203/rs.3.rs-236543/v1