Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sibylle Schirm"'
Autor:
Katja Hoffmann, Katja Cazemier, Christoph Baldow, Silvio Schuster, Yuri Kheifetz, Sibylle Schirm, Matthias Horn, Thomas Ernst, Constanze Volgmann, Christian Thiede, Andreas Hochhaus, Martin Bornhäuser, Meinolf Suttorp, Markus Scholz, Ingmar Glauche, Markus Loeffler, Ingo Roeder
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Individualization and patient-specific optimization of treatment is a major goal of modern health care. One way to achieve this goal is the application of high-resolution diagnostics together with the application of targeted thera
Externí odkaz:
https://doaj.org/article/9429451ad6684a6cab9bd77efd8baf6c
Autor:
Sibylle Schirm, Arash Haghikia, Markus Brack, Peter Ahnert, Geraldine Nouailles, Norbert Suttorp, Markus Loeffler, Martin Witzenrath, Markus Scholz
Publikováno v:
PLoS ONE, Vol 17, Iss 8 (2022)
Atherosclerosis is one of the leading causes of death worldwide. Biomathematical modelling of the underlying disease and therapy processes might be a useful aid to develop and improve preventive and treatment concepts of atherosclerosis. We here prop
Externí odkaz:
https://doaj.org/article/d5f8fdce95f44acaa30836f4e5aeae0d
Autor:
Sibylle Schirm, Peter Ahnert, Sarah Berger, Geraldine Nouailles, Sandra-Maria Wienhold, Holger Müller-Redetzky, Norbert Suttorp, Markus Loeffler, Martin Witzenrath, Markus Scholz
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243147 (2020)
Pneumonia is one of the leading causes of death worldwide. The course of the disease is often highly dynamic with unforeseen critical deterioration within hours in a relevant proportion of patients. Besides antibiotic treatment, novel adjunctive ther
Externí odkaz:
https://doaj.org/article/98075ff620534119a5616cef004a692e
Autor:
Sibylle Schirm, Peter Ahnert, Sandra Wienhold, Holger Mueller-Redetzky, Geraldine Nouailles-Kursar, Markus Loeffler, Martin Witzenrath, Markus Scholz
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156047 (2016)
Pneumonia is considered to be one of the leading causes of death worldwide. The outcome depends on both, proper antibiotic treatment and the effectivity of the immune response of the host. However, due to the complexity of the immunologic cascade ini
Externí odkaz:
https://doaj.org/article/431036da8e684a9783ee0821fea90242
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65630 (2013)
Anaemia is a common haematologic side effect of dose-dense multi-cycle cytotoxic polychemotherapy requiring erythrocyte transfusions or erythropoietin (EPO) administration. To simulate the effectiveness of different EPO application schedules, we perf
Externí odkaz:
https://doaj.org/article/3b493ed41d5443289cf5b32d55502c56
Autor:
Sibylle Schirm, Arash Haghikia, Markus Brack, Peter Ahnert, Geraldine Nouailles, Norbert Suttorp, Markus Loeffler, Martin Witzenrath, Markus Scholz
Publikováno v:
PloS one. 17(8)
Atherosclerosis is one of the leading causes of death worldwide. Biomathematical modelling of the underlying disease and therapy processes might be a useful aid to develop and improve preventive and treatment concepts of atherosclerosis. We here prop
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Purpose Although G-CSF is widely used to prevent or ameliorate leukopenia during cytotoxic chemotherapies, its optimal use is still under debate and depends on many therapy parameters such as dosing and timing of cytotoxic drugs and G-CSF, G-CSF phar
Autor:
Yvonne Gräser, Abir Saraswat, Saumya Panda, Resham Vasani, Cornelia Wiegand, Daniela Koch, Sibylle Schirm, Sanjeev Gupta, Rengarajan Madhu, Pietro Nenoff, Anke Burmester, Uwe Paasch, Shyam B Verma, Constanze Krüger, Shital Poojary, Mahendra M Kura, Andreas Ebert, Karine Salamin, Akshy Kumar, Archana Singal, Anupam Das, Franziska Wittig, Michel Monod, Silke Uhrlaß, Uta-Christina Hipler
Publikováno v:
MycosesREFERENCES. 63(7)
Background An alarming increase in recalcitrant dermatophytosis has been witnessed in India over the past decade. Drug resistance may play a major role in this scenario. Objectives The aim of the present study was to determine the prevalence of in vi
Publikováno v:
Theoretical Biology & Medical Modelling
Background Haematotoxicity of conventional chemotherapies often results in delays of treatment or reduction of chemotherapy dose. To ameliorate these side-effects, patients are routinely treated with blood transfusions or haematopoietic growth factor
Autor:
Markus Loeffler, Michael Pfreundschuh, Marita Ziepert, Carsten Zwick, Samira Zeynalova, Markus Scholz, Sibylle Schirm
Publikováno v:
Annals of hematology. 92(12)
Bi-weekly (R)-CHOP therapy is one of the standard treatmentS for elderly patients with aggressive B-cell lymphoma, but it is only feasible with supportive G-CSF treatment. In the trials of the DSHNHL, either unpegylated G-CSF was given daily over 7 o