Zobrazeno 1 - 10 of 33 pro vyhledávání: '"Sibylle Pscherer"'
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Parallel evaluation of cell‑based phage display panning strategies: Optimized selection and depletion steps result in AML blast‑binding consensus antibodies
Autor: Natalja Rutz, Andrea Teigler‑Schlegel, Ulrike Gamerdinger, Theresa Weber, Mehmet Kemal Tur, Wolfgang Blau, Sibylle Pscherer, Mathias J. Rummel, Stefan Gattenlöhner
Publikováno v: Molecular Medicine Reports
Phage display technology (PD) is a powerful technique for the generation of tumor‑targeting antibodies. However, there are a number of different selection methods established in different laboratories around the world. Cell‑based PD panning metho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82071aef984512b8e6fce804b3447d4b
https://pubmed.ncbi.nlm.nih.gov/34490477
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4
Development of a monoclonal sandwich ELISA for direct detection of bluetongue virus 8 in infected animals
Autor: Mehmet Kemal Tur, Hans-Peter Hamann, Sibylle Pscherer, Hans Ulrich Eskens, Andre ten Haaf, Johannes Kohl, Stefan Gattenlöhner, Max Bastian
Publikováno v: Journal of Virological Methods. 243:172-176
Bluetongue is an infectious viral disease which can cause mortality in affected ruminants, and tremendous economic damage via impacts upon fertility, milk production and the quality of wool. The disease is caused by bluetongue virus (BTV) which is tr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73dc9fd7dd1e3569416256f9571b4c20
https://doi.org/10.1016/j.jviromet.2017.02.003
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5
Common Ewing sarcoma-associated antigens fail to induce natural T cell responses in both patients and healthy individuals
Autor: Claudia Rossig, Heribert Juergens, Sareetha Kailayangiri, Ilka Neumann, Nadine Theimann, Martina Ahlmann, Anna Hansmeier, Bianca Altvater, Jendrik Hardes, Nicole Farwick, Sibylle Pscherer, Georg Gosheger, Gabriele Mrachatz, Christiane Chen
Publikováno v: Cancer Immunology, Immunotherapy. 63:1047-1060
Disseminated or relapsed Ewing sarcoma (EwS) has remained fatal in the majority of patients. A promising approach to preventing relapse after conventional therapy is to establish tumor antigen-specific immune control. Efficient and specific T cell me
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423961f1921349da2588951c028e6723
https://doi.org/10.1007/s00262-014-1574-3
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8
The ganglioside antigen GD2 is surface-expressed in Ewing sarcoma and allows for MHC-independent immune targeting
Autor: Jutta Meltzer, Jendrik Hardes, A. Luecke, Sibylle Pscherer, Silke Landmeier, Georg Gosheger, Bianca Altvater, Marc Hotfilder, C. Dierkes, Heribert Juergens, Sareetha Kailayangiri, K. Leuchte, U. Titze, Uta Dirksen, Claudia Rossig
Publikováno v: British Journal of Cancer
Background: Novel treatment strategies are needed to cure disseminated Ewing sarcoma. Primitive neuroectodermal features and a mesenchymal stem cell origin are both compatible with aberrant expression of the ganglioside antigen GD2 and led us to expl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d8a5df448b7bbdeeb061954cdaef10
https://doi.org/10.1038/bjc.2012.57
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9
Activated human γδ T cells induce peptide-specific CD8+ T-cell responses to tumor-associated self-antigens
Autor: Sibylle Pscherer, Silke Landmeier, Heribert Juergens, Claudia Rossig, Sareetha Kailayangiri, Bianca Altvater, Barbara Savoldo
Publikováno v: Cancer Immunology, Immunotherapy. 61:385-396
Specific cellular immunotherapy of cancer requires efficient generation and expansion of cytotoxic T lymphocytes (CTLs) that recognize tumor-associated self-antigens. Here, we investigated the capacity of human γδ T cells to induce expansion of CD8
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16a0f2922d85803fee9afbe0c7a3239
https://doi.org/10.1007/s00262-011-1111-6
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10
2B4 (CD244) Signaling by Recombinant Antigen-specific Chimeric Receptors Costimulates Natural Killer Cell Activation to Leukemia and Neuroblastoma Cells
Autor: Dario Campana, Jaane Temme, Heribert Juergens, Bianca Altvater, Sareetha Kailayangiri, Katharina Schweer, Sibylle Pscherer, Martin Pule, Silke Landmeier, Claudia Rossig
Publikováno v: Clinical Cancer Research. 15:4857-4866
Purpose: Novel natural killer (NK) cell–directed strategies in cancer immunotherapy aim at specifically modulating the balance between NK cell receptor signals toward tumor-specific activation. The signaling lymphocyte activation molecule–related
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74dcd2d1fc892487ef2cb50c4db6a415
https://doi.org/10.1158/1078-0432.ccr-08-2810
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