Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sibylle Kiel"'
Publikováno v:
Neurochemistry International. 47:196-203
In the present study on transfected human embryonic kidney (HEK)293 cells, we aimed at establishing whether expression of the naturally occurring Thr 92 Lys variation of the G s -coupled h5-HT 7(a) receptor leads to changes of ligand binding properti
Autor:
Hans Jürgen Grote, Helmut E. Gabbert, Viola Schmiemann, Rainer Kappes, Sibylle Kiel, Alfred Böcking, Mario Sarbia
Publikováno v:
International Journal of Cancer. 110:751-755
Promoter hypermethylation is a major mechanism for gene silencing and offers a promising starting point for developing molecular biomarkers. The purpose of our study was to determine aberrant methylation of the adenomatous polyposis coli (APC) gene p
Autor:
Andrea R. Florl, Sibylle Kiel, Helmut E. Gabbert, Helene Geddert, Mario Sarbia, Thomas Krieg, Erol Iskender, Sandra Vossen
Publikováno v:
International Journal of Cancer. 110:208-211
Using methylation-specific real-time PCR, we determined the prevalence of aberrant methylation in the mismatch repair gene hMLH1 and in the recently described HPP1 gene among 50 esophageal, 50 cardiac and 50 gastric ADCs. Additionally, expression of
Publikováno v:
Human Pathology. 34:850-856
p63, a member of the p53 gene family, is known to encode functionally antagonistic protein isoforms. Although transactivating protein isoforms display p53-like functions, deltaNp63 isoforms act toward p53 in a dominant negative way. Using immunohisto
Publikováno v:
Pharmacogenetics. 13:119-126
The aim of this study, performed in stably transfected HEK293 cells, was to investigate whether expression of the naturally occurring Pro 279 Leu variant of the h5.HT 7(a) receptor (located in the third intracellular loop) is associated with changes
Autor:
Mario Sarbia, Reinhart Willers, Helene Geddert, Jian-Hui Zhang, Helmut E. Gabbert, Sibylle Kiel, Rainer B. Zotz
Publikováno v:
Journal of cancer research and clinical oncology. 131(12)
Purpose: We investigated the prevalence of single nucleotide polymorphisms in the p16 gene (C540G) and the cyclin D1 gene (G870A), both known to regulate function in G1 arrest and therefore, may play an important role in carcinogenesis. Methods: Usin
Publikováno v:
Neurochemistry international. 47(3)
In the present study on transfected human embryonic kidney (HEK)293 cells, we aimed at establishing whether expression of the naturally occurring Thr92Lys variation of the Gs-coupled h5-HT7(a) receptor leads to changes of ligand binding properties, o
Publikováno v:
Pharmacogenetics. 13(2)
The aim of this study, performed in stably transfected HEK293 cells, was to investigate whether expression of the naturally occurring Pro279Leu variant of the h5-HT7(a) receptor (located in the third intracellular loop) is associated with changes in