Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sibylle Bürgi"'
Autor:
Johnny Deladoëy, Amélie Besson, Souzan Salemi, Andrée Eblé, Ulrich E. Honegger, Jean-Marc Vuissoz, Primus-Eugen Mullis, Martin Bidlingmaier, Christa E. Flück, Sibylle Bürgi
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 90:2493-2499
Human GH has two disulfide bridges linking Cys-53 to Cys-165 and Cys-182 to Cys-189. Although absence of the first disulfide bridge has been shown to affect the bioactivity of GH in transgenic mice, little is known of the importance of this bridge in
Publikováno v:
The Journal of biological chemistry. 278(2)
Reduction in surface beta(1)-adrenoceptor (beta1AR) density is thought to play a critical role in mediating the therapeutic long term effects of antidepressants. Since antidepressants are neither agonists nor antagonists for G protein-coupled recepto
Publikováno v:
Planta Medica. 72:1436-1437
The mode of action of antidepressants is still a matter of debate. Acute inhibition of neurotransmitter reuptake in central neuronal synapses, followed by a down-regulation of central postsynaptic beta-adrenoceptor (beta-AR) numbers were consistently