Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sibylle, Jäger"'
Autor:
Simon-Pierre Gravel, Youcef Ben Khalifa, Shawn McGuirk, Catherine St-Louis, Karl M. Laurin, Émilie Lavallée, Damien Benas, Stéphanie Desbouis, Frédéric Amaral, Damien D’Amours, Lionel Breton, Sibylle Jäger, Julie St-Pierre
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106314- (2023)
Summary: Skin plays central roles in systemic physiology, and it undergoes significant functional changes during aging. Members of the peroxisome proliferator-activated receptor-gamma coactivator (PGC-1) family (PGC-1s) are key regulators of the biol
Externí odkaz:
https://doaj.org/article/bc82a40fa2f84307b15f55c7f9f47f76
Autor:
Elodie Gras, Lavigne, Andrea, Cavagnino, Rémy, Steinschneider, Lionel, Breton, Martin A, Baraibar, Sibylle, Jäger
Publikováno v:
Free Radical Biology and Medicine. 181:98-104
Increased protein carbonylation is a hallmark of oxidative stress, protein homeostasis dysregulation and aging in the nervous system and skin. Sensory neurons interact with skin cells and are involved in skin homeostasis. We have previously reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9d591025e13ba404aaed80e1a03dd4
https://doi.org/10.1016/j.freeradbiomed.2022.01.029
https://doi.org/10.1016/j.freeradbiomed.2022.01.029
Autor:
Steve Thomas Pannakal, Sibylle Jäger, Albert Duranton, Amit Tewari, Subarna Saha, Aneesha Radhakrishnan, Nita Roy, Jean François Kuntz, Soraya Fermas, Darryl James, Jane Mellor, Namita Misra, Lionel Breton
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0179813 (2017)
The traditional Indian medicine, Ayurveda, provides insights and practical solutions towards a healthy life style. Rasayana is a branch of Ayurveda known for preserving and promoting health, enhancing the quality of life and delaying the aging proces
Externí odkaz:
https://doaj.org/article/df6e3869af7a42b5bf2ea6da8203b367
Autor:
Mélanie Salamito, Benjamin Gillet, Delfien Syx, Elisabeth Vaganay, Marilyne Malbouyres, Catherine Cerutti, Nicolas Tissot, Chloé Exbrayat-Héritier, Philippe Perez, Christophe Jones, Sandrine Hughes, Fransiska Malfait, Valérie Haydont, Sibylle Jäger, Florence Ruggiero
Publikováno v:
Journal of Investigative Dermatology
Journal of Investigative Dermatology, 2022, 109, pp.1-18. ⟨10.1016/j.jid.2022.07.034⟩
Journal of Investigative Dermatology, 2022, 109, pp.1-18. ⟨10.1016/j.jid.2022.07.034⟩
International audience; NRF2 is a master regulator of anti-oxidative response that was recently proposed as a potential regulator of extracellular matrix (ECM) gene expression. Fibroblasts are major ECM producers in all connective tissues including d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d556c4c02cc465795a413eac2d385170
https://doi.org/10.1016/j.jid.2022.07.034
https://doi.org/10.1016/j.jid.2022.07.034
Autor:
Vipul Gupta, Yukiko Matsuoka, Xavier Marat, Alina Crudu, Samik Ghosh, Sibylle Jäger, Hiroaki Kitano, Lionel Breton, Roger Rozot
Publikováno v:
NPJ Systems Biology and Applications
npj Systems Biology and Applications, Vol 5, Iss 1, Pp 1-10 (2019)
npj Systems Biology and Applications, Vol 5, Iss 1, Pp 1-10 (2019)
Designing alternative approaches to efficiently screen chemicals on the efficacy landscape is a challenging yet indispensable task in the current compound profiling methods. Particularly, increasing regulatory restrictions underscore the need to deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b51b7840bb8614b175c7c8dd211c29a0
https://doi.org/10.1038/s41540-019-0119-y
https://doi.org/10.1038/s41540-019-0119-y
Autor:
Sibylle Jäger, Christian Tran, Maria Dalko-Csiba, Anne-Marie Minondo, Jean-François Michelet, Florian Formanek, Philippe Bastien, Hugues Lortat-Jacob, Elodie Henriet, Lionel Breton, Romain R. Vivès
Publikováno v:
Biochimica et Biophysica Acta (BBA)-General Subjects
Biochimica et Biophysica Acta (BBA)-General Subjects, Elsevier, 2017, 1861 (9), pp.2250-2260. ⟨10.1016/j.bbagen.2017.06.006⟩
Biochimica et Biophysica Acta (BBA)-General Subjects, 2017, 1861 (9), pp.2250-2260. ⟨10.1016/j.bbagen.2017.06.006⟩
Biochimica et Biophysica Acta (BBA)-General Subjects, Elsevier, 2017, 1861 (9), pp.2250-2260. ⟨10.1016/j.bbagen.2017.06.006⟩
Biochimica et Biophysica Acta (BBA)-General Subjects, 2017, 1861 (9), pp.2250-2260. ⟨10.1016/j.bbagen.2017.06.006⟩
Background Jasmonates are plant hormones that exhibit anti-cancer and anti-inflammatory properties and have therefore raised interest for human health applications. The molecular basis of these activities remains poorly understood, although increasin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6801740c77589f5bebec0c67b0f94539
https://hal.archives-ouvertes.fr/hal-01553681
https://hal.archives-ouvertes.fr/hal-01553681
Autor:
Lionel Breton, Julie St-Pierre, Hugo Aguilaniu, Mehrnaz Shamalnasab, Sibylle Jäger, Simon-Pierre Gravel
Publikováno v:
Aging Cell
Plant extracts containing salicylates are probably the most ancient remedies to reduce fever and ease aches of all kind. Recently, it has been shown that salicylates activate adenosine monophosphate‐activated kinase (AMPK), which is now considered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c812e747b953d9a133227fb7346aa1
https://doi.org/10.1111/acel.12830
https://doi.org/10.1111/acel.12830
Autor:
Marcus P. Cooper, Saverio Cinti, Monia Manieri, Melina C. Fan, Mi X. Donovan, Katrin S. Lindenberg, Dimitri Krainc, Lindsay M. Rohas, Sibylle Jäger, Pei Hsuan Wu, Jiandie D. Lin, Vamsi K. Mootha, Chen-Yu Zhang, Ann Marie Zavacki, Bradford B. Lowell, Paul T. Tarr, Richard M. Reznick, Julie St-Pierre, Claudia R. Vianna, Bruce M. Spiegelman, Libin Cui, Zhidan Wu, Gerald I. Shulman
Publikováno v:
Cell. 119:121-135
PGC-1alpha is a coactivator of nuclear receptors and other transcription factors that regulates several metabolic processes, including mitochondrial biogenesis and respiration, hepatic gluconeogenesis, and muscle fiber-type switching. We show here th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::903cc67efc88f3366a376cfa1382ef19
https://doi.org/10.1016/j.cell.2004.09.013
https://doi.org/10.1016/j.cell.2004.09.013
Publikováno v:
The EMBO Journal. 20:4423-4431
In eukaryotes, the ubiquitin–proteasome system plays a major role in selective protein breakdown for cellular regulation. Here we report the discovery of a new essential component of this degradation machinery. We found the Saccharomyces cerevisiae
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8ca68358bd692d1f8c3e03d9ec1f2b3
https://doi.org/10.1093/emboj/20.16.4423
https://doi.org/10.1093/emboj/20.16.4423
Autor:
Marc Uldry, Sibylle Jäger, Christoph Handschin, Lindsay M. Rohas, Bruce M. Spiegelman, Julie St-Pierre
Maintenance of ATP levels is a critical feature of all cells. Mitochondria are responsible for most ATP synthesis in eukaryotes. We show here that mammalian cells respond to a partial chemical uncoupling of mitochondrial oxidative phosphorylation wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6af8be59ac5b229ad6aeb71a0261a4d