Výsledky vyhledávání

Biologic role of activated leukocyte cell adhesion molecule overexpression in breast cancer cell lines and clinical tumor tissue

Autor: Sylke Krenkel, Sibyll Hein, M. Ihnen, Sabine Riethdorf, Nadine Köhler, Michaela Schweizer, Klaus Pantel, Katrin Beck, Thomas Streichert, Fritz Jänicke, Rana Issa, Harriet Wikman, Volkmar Müller, Volker Assmann, Karin Milde-Langosch

Publikováno v: Breast Cancer Research and Treatment. 129:347-360

The activated leukocyte cell adhesion molecule (ALCAM) is overexpressed in many mammary tumors, but controversial results about its role and prognostic impact in breast cancer have been reported. Therefore, we evaluated the biologic effects of ALCAM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce36433a877e6e125d6c0c7adee18478
https://doi.org/10.1007/s10549-010-1219-y

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C-Fos expression is a molecular predictor of progression and survival in epithelial ovarian carcinoma

Autor: C. Baasch, Sven Mahner, Sibyll Hein, Linn Wölber, Karin Milde-Langosch, J. Schwarz, Fritz Jänicke

Publikováno v: British Journal of Cancer

Members of the Fos protein family dimerise with Jun proteins to form the AP-1 transcription factor complex. They have a central function in proliferation and differentiation of normal tissue as well as in oncogenic transformation and tumour progressi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38dc4bfab6fe2f58b4be42678e71b598
https://doi.org/10.1038/sj.bjc.6604650

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Sodium-Dependent myo -Inositol Transporter 1 Is a Cellular Receptor for Mus cervicolor M813 Murine Leukemia Virus

Autor: Carol Stocking, Susan R. Ross, Jürgen Löhler, Dmitry Ivanov, Vladimir S. Prassolov, Sibyll Hein, Yuanming Zhang

Publikováno v: Journal of Virology. 77:5926-5932

Retrovirus infection is initiated by binding of the surface (SU) portion of the viral envelope glycoprotein (Env) to specific receptors on cells. This binding triggers conformational changes in the transmembrane portion of Env, leading to membrane fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93fa20edd8c310433741576a1c301a41
https://doi.org/10.1128/jvi.77.10.5926-5932.2003

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Transient expression of PU.1 commits multipotent progenitors to a myeloid fate whereas continued expression favors macrophage over granulocyte differentiation

Autor: Ursula Just, Heike Fiegler, Sibyll Hein, Carol Stocking, Michael Cross, Zoe McIvor, Timm Schroeder

Publikováno v: Experimental Hematology. 31:39-47

Objective The Ets-family transcription factor PU.1 is expressed specifically in the hematopoietic system, in which it is absolutely required for the generation of B lymphocytes and macrophages. In contrast, overexpression of PU.1 blocks terminal diff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd70bd363f6e4b3b4c56ca6e9841a4f5
https://doi.org/10.1016/s0301-472x(02)01017-2

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The Mus cervicolor MuLV Isolate M813 Is Highly Fusogenic and Induces a T-Cell Lymphoma Associated with Large Multinucleated Cells

Autor: Dmitry Ivanov, Carol Stocking, Vladimir Prassolov, Gabriel Rutter, Sibyll Hein, Carsten Münk, Jürgen Löhler

Publikováno v: Virology. 290(1):39-49

M813 is a type-C murine leukemia virus (MuLV) isolated from the Asian rodent Mus cervicolor. We have recently demonstrated that M813 defines a distinct MuLV receptor interference group. Here we show that M813 rapidly induces fusion of MuLV-expressing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1aab81f48b40363389debc9944c8f5

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Mus cervicolor Murine Leukemia Virus Isolate M813 Belongs to a Unique Receptor Interference Group

Autor: Carol Stocking, Marion Ziegler, Carsten Münk, Vladimir S. Prassolov, Sibyll Hein, Dmitry Ivanov, Jürgen Löhler

Publikováno v: Journal of Virology. 75:4490-4498

Murine leukemia virus (MuLV) M813 was originally isolated from the Southeast Asian rodent Mus cervicolor . As with the ecotropic MuLVs derived from Mus musculus , its host range is limited to rodent cells. Earlier studies have mapped its receptor to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e103561836d5b5fdda31feaa952b2dd
https://doi.org/10.1128/jvi.75.10.4490-4498.2001

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