Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sibgat Choudhury"'
Autor:
Lina Ding, Ying Su, Anne Fassl, Kunihiko Hinohara, Xintao Qiu, Nicholas W. Harper, Sung Jin Huh, Noga Bloushtain-Qimron, Bojana Jovanović, Muhammad Ekram, Xiaoyuan Zi, William C. Hines, Maša Alečković, Carlos Gil del Alcazar, Ryan J. Caulfield, Dennis M. Bonal, Quang-De Nguyen, Vanessa F. Merino, Sibgat Choudhury, Gabrielle Ethington, Laura Panos, Michael Grant, William Herlihy, Alfred Au, Gedge D. Rosson, Pedram Argani, Andrea L. Richardson, Deborah Dillon, D. Craig Allred, Kirsten Babski, Elizabeth Min Hui Kim, Charles H. McDonnell, Jon Wagner, Ron Rowberry, Kristie Bobolis, Celina G. Kleer, E. Shelley Hwang, Joanne L. Blum, Simona Cristea, Piotr Sicinski, Rong Fan, Henry W. Long, Saraswati Sukumar, So Yeon Park, Judy E. Garber, Mina Bissell, Jun Yao, Kornelia Polyak
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Myoepithelial cells prevent tumour growth and invasion in DCIS. Here, the authors show that p63 and TCF7 cooperate to regulate a transcription factor network for the maintenance of normal myoepithelial function and altered expression of these genes p
Externí odkaz:
https://doaj.org/article/784cf49197cf4d50824d3974f6c39d75
Autor:
Sung Jin Huh, Kendell Clement, David Jee, Alessandra Merlini, Sibgat Choudhury, Reo Maruyama, Ronnie Yoo, Anna Chytil, Patrick Boyle, Fei Ann Ran, Harold L. Moses, Mary Helen Barcellos-Hoff, Laurie Jackson-Grusby, Alexander Meissner, Kornelia Polyak
Publikováno v:
Stem Cell Reports, Vol 4, Iss 2, Pp 297-311 (2015)
Postnatal mammary gland development and differentiation occur during puberty and pregnancy. To explore the role of DNA methylation in these processes, we determined the genome-wide DNA methylation and gene expression profiles of CD24+CD61+CD29hi, CD2
Externí odkaz:
https://doaj.org/article/e4fb6000f9f5445093db53612eb10e4a
Autor:
Reo Maruyama, Sibgat Choudhury, Adam Kowalczyk, Marina Bessarabova, Bryan Beresford-Smith, Thomas Conway, Antony Kaspi, Zhenhua Wu, Tatiana Nikolskaya, Vanessa F Merino, Pang-Kuo Lo, X Shirley Liu, Yuri Nikolsky, Saraswati Sukumar, Izhak Haviv, Kornelia Polyak
Publikováno v:
PLoS Genetics, Vol 7, Iss 4, p e1001369 (2011)
Differentiation is an epigenetic program that involves the gradual loss of pluripotency and acquisition of cell type-specific features. Understanding these processes requires genome-wide analysis of epigenetic and gene expression profiles, which have
Externí odkaz:
https://doaj.org/article/d4b3642e06ac4e1f994d1ffc664b3e25
Autor:
Fred Saad, Philip Kantoff, Jonathan I. Epstein, Mathieu Latour, Cristina Magi-Galluzzi, Eric A. Klein, Massimo Loda, James Dunyak, Julie Nardone, Eldar Giladi, Hua Chang, Alex Kaprelyants, Aeron Hurley, Christina Ernst, Louis Coupal, Teresa Capela, Sibgat Choudhury, Clayton Small, Thomas P. Nifong, Mathew Putzi, Michail Shipitsin, David L. Rimm, David M. Berman, Peter Blume-Jensen
Purpose: Prostate cancer aggressiveness and appropriate therapy are routinely determined following biopsy sampling. Current clinical and pathologic parameters are insufficient for accurate risk prediction leading primarily to overtreatment and also m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a1d5ad71950008144484ceac754a37
https://doi.org/10.1158/1078-0432.c.6524298
https://doi.org/10.1158/1078-0432.c.6524298
Autor:
Fred Saad, Philip Kantoff, Jonathan I. Epstein, Mathieu Latour, Cristina Magi-Galluzzi, Eric A. Klein, Massimo Loda, James Dunyak, Julie Nardone, Eldar Giladi, Hua Chang, Alex Kaprelyants, Aeron Hurley, Christina Ernst, Louis Coupal, Teresa Capela, Sibgat Choudhury, Clayton Small, Thomas P. Nifong, Mathew Putzi, Michail Shipitsin, David L. Rimm, David M. Berman, Peter Blume-Jensen
Supplementary Methods, Table S1, Figures S1-7. Methods for quantitative multiplex proteomics imaging (QMPI) Clinical studies: Statistical plan Table S1. Clinical Validation Study. Comparison of Predictive Value of the 8-Biomarker Assay for Favorable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a775876007c847964815ceef0082305
https://doi.org/10.1158/1078-0432.22459749
https://doi.org/10.1158/1078-0432.22459749
Autor:
Fred Saad, Genevieve Saad, Anne-Marie Mes-Masson, Kevin C. Zorn, Gang Han, Amol Prakash, Mathieu Latour, Sibgat Choudhury, Jerome P. Richie, Jean-Baptiste Lattouf, Veronique Ouellet, Pierre I. Karakiewicz, Hugues Widmer
Publikováno v:
Journal of Urology. 197:1034-1040
Current clinicopathological parameters are insufficient to predict the likelihood of biochemical recurrence in patients with prostate cancer after radical prostatectomy. Such information may help identify patients who would likely benefit from adjuva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d59f12960473b4ed1084727536717a07
https://doi.org/10.1016/j.juro.2016.09.116
https://doi.org/10.1016/j.juro.2016.09.116
Autor:
Dennis M. Bonal, Nicholas W. Harper, Judy Garber, Maša Alečković, Kunihiko Hinohara, Carlos R. Gil Del Alcazar, Ron Rowberry, Vanessa F. Merino, Xintao Qiu, Celina G. Kleer, Mina J. Bissell, Henry W. Long, Ying Su, Pedram Argani, William Herlihy, Michael Grant, Gabrielle Ethington, Noga Bloushtain-Qimron, Joanne L. Blum, Muhammad B. Ekram, Laura Panos, Sibgat Choudhury, Saraswati Sukumar, Jon Wagner, Gedge D. Rosson, So Yeon Park, Kirsten Babski, William C. Hines, Quang-Dé Nguyen, Sung Jin Huh, Piotr Sicinski, Deborah A. Dillon, Simona Cristea, Anne Fassl, D. Craig Allred, Rong Fan, Lina Ding, Kristie Bobolis, Elizabeth Min Hui Kim, Bojana Jovanovic, Xiaoyuan Zi, Alfred Au, Charles H. McDonnell, Jun Yao, E. Shelley Hwang, Andrea L. Richardson, Kornelia Polyak, Ryan J. Caulfield
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature communications, vol 10, iss 1
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature communications, vol 10, iss 1
Myoepithelial cells play key roles in normal mammary gland development and in limiting pre-invasive to invasive breast tumor progression, yet their differentiation and perturbation in ductal carcinoma in situ (DCIS) are poorly understood. Here, we in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32182628c12411f6fa9858fb01aed741
https://pubmed.ncbi.nlm.nih.gov/31519911
https://pubmed.ncbi.nlm.nih.gov/31519911
Autor:
Sibgat Choudhury, J. Dunyak, David M. Berman, Aeron D. Hurley, Eric A. Klein, Julie Nardone, Louis Coupal, Thomas P. Nifong, Fred Saad, Peter Blume-Jensen, David L. Rimm, Teresa Capela, Massimo Loda, Philip W. Kantoff, Hua Chang, Mathieu Latour, Christina Ernst, Cristina Magi-Galluzzi, Mathew Putzi, Clayton Small, Alex Kaprelyants, Michail Shipitsin, Jonathan I. Epstein, Eldar Giladi
Publikováno v:
Clinical Cancer Research. 21:2591-2600
Purpose: Prostate cancer aggressiveness and appropriate therapy are routinely determined following biopsy sampling. Current clinical and pathologic parameters are insufficient for accurate risk prediction leading primarily to overtreatment and also m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31eb2c1aa00338ec8a958933a4326487
https://doi.org/10.1158/1078-0432.ccr-14-2603
https://doi.org/10.1158/1078-0432.ccr-14-2603
Autor:
Julie Nardone, Peter Blume-Jensen, Massimo Loda, Christina Ernst, Shaun A. Hussain, Thomas P. Nifong, David L. Rimm, S Friedlander, Sibgat Choudhury, Y E Huang, Michail Shipitsin, Catherine B. Small, David M. Berman, H. Chang, Aeron D. Hurley, J. Dunyak, Eldar Giladi
Publikováno v:
British Journal of Cancer
Background: Key challenges of biopsy-based determination of prostate cancer aggressiveness include tumour heterogeneity, biopsy-sampling error, and variations in biopsy interpretation. The resulting uncertainty in risk assessment leads to significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ef42de7cd2594c8dbcc3bd61e5370a8
http://europepmc.org/articles/PMC4453845
http://europepmc.org/articles/PMC4453845
Autor:
William C. Hahn, Jessica J. Kim, So Young Kim, David E. Root, Andrea L. Richardson, Hee Eun Lee, So Yeon Park, Yuri Nikolsky, Zhenhua Wu, Sibgat Choudhury, X. Shirley Liu, Laura Mulvey, Serena J. Silver, Tatiana Nikolskaya, Mithat Gonen, Marina Bessarabova, Karen S. Anderson, Andriy Marusyk, Reo Maruyama, Vanessa Almendro, David A. Frank, Noga Bloushtain-Qimron, Janina Schemme, Sung Jin Huh, Sarah R. Walker, Lauren L. C. Marotta, Kornelia Polyak, Michail Shipitsin
Publikováno v:
Journal of Clinical Investigation. 121:2723-2735
Intratumor heterogeneity is a major clinical problem because tumor cell subtypes display variable sensitivity to therapeutics and may play different roles in progression. We previously characterized 2 cell populations in human breast tumors with dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf6f740dabc0175cdd6f322612a1a69
https://doi.org/10.1172/jci44745
https://doi.org/10.1172/jci44745