Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Sibel I. Karchner"'
Autor:
Jeffrey T. Miller, Bryan W. Clark, Noah M. Reid, Sibel I. Karchner, Jennifer L. Roach, Mark E. Hahn, Diane Nacci, Andrew Whitehead
Publikováno v:
Evolutionary Applications, Vol 17, Iss 1, Pp n/a-n/a (2024)
Abstract The genetic architecture of phenotypic traits can affect the mode and tempo of trait evolution. Human‐altered environments can impose strong natural selection, where successful evolutionary adaptation requires swift and large phenotypic sh
Externí odkaz:
https://doaj.org/article/a4d6527241e34b67a55a2ecbf3d98517
Autor:
Bryan D. James, Sibel I. Karchner, Anna N. Walsh, Neelakanteswar Aluru, Diana G. Franks, Kallen R. Sullivan, Christopher M. Reddy, Collin P. Ward, Mark E. Hahn
Publikováno v:
Environmental Science & Technology.
Publikováno v:
Toxicol Sci
Chemical modifications of proteins, DNA and RNA moieties play critical roles in regulating gene expression. Emerging evidence suggests these RNA modifications (epitranscriptomics) have substantive roles in basic biological processes. One of the most
Autor:
Cory A. Berger, Collin P. Ward, Sibel I. Karchner, Robert K. Nelson, Christopher M. Reddy, Mark E. Hahn, Ann M. Tarrant
Publikováno v:
Marine environmental research. 175
Crude oil released into the environment undergoes weathering processes that gradually change its composition and toxicity. Co-exposure to petroleum mixtures and other stressors, including ultraviolet (UV) radiation, may lead to synergistic effects an
Autor:
Mark E Hahn, Andrew G McArthur, Sibel I Karchner, Diana G Franks, Matthew J Jenny, Alicia R Timme-Laragy, John J Stegeman, Bruce R Woodin, Michael J Cipriano, Elwood Linney
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113158 (2014)
Oxidative stress is an important mechanism of chemical toxicity, contributing to teratogenesis and to cardiovascular and neurodegenerative diseases. Developing animals may be especially sensitive to chemicals causing oxidative stress. The development
Externí odkaz:
https://doaj.org/article/9f04281701d54484a502ec62aef1c01a
Autor:
Libe, Aranguren-Abadía, Roger, Lille-Langøy, Alexander K, Madsen, Sibel I, Karchner, Diana G, Franks, Fekadu, Yadetie, Mark E, Hahn, Anders, Goksøyr, Odd André, Karlsen
Publikováno v:
Environ Sci Technol
The aryl hydrocarbon receptor (Ahr) is a ligand-activated transcription factor that mediates the toxicity of halogenated and polycyclic aromatic hydrocarbons in vertebrates. Atlantic cod (Gadus morhua) has recently emerged as a model organism in envi
Publikováno v:
Toxicol Sci
Polychlorinated biphenyls (PCBs) are highly persistent and ubiquitously distributed environmental pollutants. Based on their chemical structure, PCBs are classified into non-ortho-substituted and ortho-substituted congeners. Non-ortho-substituted PCB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a79a046b86b168a5e17cfa0c42f930b
https://europepmc.org/articles/PMC6944218/
https://europepmc.org/articles/PMC6944218/
Autor:
David C. Lamb, John J. Stegeman, Mark E. Hahn, Sibel I. Karchner, Jean-François Rees, Jared V. Goldstone, Benjamin Lemaire, Jeffrey C. Drazen
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1866:155-165
Limited knowledge of the molecular evolution of deep-sea fish proteomes so far suggests that a few widespread residue substitutions in cytosolic proteins binding hydrophilic ligands contribute to resistance to the effects of high hydrostatic pressure
Autor:
Sibel I. Karchner, Diane Nacci, Erika B. Holland, Andrew Whitehead, Bryan W. Clark, Noah M. Reid, Isaac N. Pessah, John J. Stegeman, Mark E. Hahn, Jared V. Goldstone
Publikováno v:
Aquatic Toxicology. 192:105-115
Non-dioxin-like polychlorinated biphenyls (NDL PCBs) activate ryanodine receptors (RyR), microsomal Ca2+ channels of broad significance. Teleost fish may be important models for NDL PCB neurotoxicity, and we used sequencing databases to characterize
Publikováno v:
Toxicological Sciences. 160:386-397
Early life exposure to environmental chemicals can have long-term consequences that are not always apparent until later in life. We recently demonstrated that developmental exposure of zebrafish to low, nonembryotoxic levels of 3,3’,4,4’,5-pentac