Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Sibel, Saya"'
Autor:
Sibel Saya, Patty Chondros, Anastasia Abela, Cathrine Mihalopolous, Mary Lou Chatterton, Jane Gunn, Timothy F. Chen, Thomas M. Polasek, Elise Dettmann, Rachel Brooks, Michelle King, Luke Spencer, Pavithran Alphonse, Shakira Milton, Georgia Ramsay, Zoe Siviour, Jamie Liew, Philip Ly, Matthew Thoenig, Raushaan Seychell, Floriana La Rocca, Luke B. Hesson, Nydia Mejias, Terri Sivertsen, Melanie Anne Galea, Chad Bousman, Jon Emery
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-18 (2023)
Abstract Background The evidence for the clinical utility of pharmacogenomic (PGx) testing is growing, and guidelines exist for the use of PGx testing to inform prescribing of 13 antidepressants. Although previous randomised controlled trials of PGx
Externí odkaz:
https://doaj.org/article/55d8406932cd4f07b01ea962249ddd20
Autor:
Alexander Dias, Mark N. Brook, Elizabeth K. Bancroft, Elizabeth C. Page, Anthony Chamberlain, Sibel Saya, Jan Amin, Christos Mikropoulos, Natalie Taylor, Kathryn Myhill, Sarah Thomas, Edward Saunders, Tokhir Dadaev, Daniel Leongamornlert, Thomas Dyrsø Jensen, D. Gareth Evans, Cezary Cybulski, Annelie Liljegren, Soo H. Teo, Lucy Side, The IMPACT study collaborators and Steering Committee, Zsofia Kote‐Jarai, Rosalind A. Eeles
Publikováno v:
BJUI Compass, Vol 4, Iss 3, Pp 361-373 (2023)
Abstract Objectives The relation of serum androgens and the development of prostate cancer (PCa) is subject of debate. Lower total testosterone (TT) levels have been associated with increased PCa detection and worse pathological features after treatm
Externí odkaz:
https://doaj.org/article/c2f7c922836941d782022c8f8f942952
Autor:
Sibel Saya, Lucy Boyd, Patty Chondros, Mairead McNamara, Michelle King, Shakira Milton, Richard De Abreu Lourenco, Malcolm Clark, George Fishman, Julie Marker, Cheri Ostroff, Richard Allman, Fiona M. Walter, Daniel Buchanan, Ingrid Winship, Jennifer McIntosh, Finlay Macrae, Mark Jenkins, Jon Emery
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-19 (2022)
Abstract Background Polygenic risk scores (PRSs) can predict the risk of colorectal cancer (CRC) and target screening more precisely than current guidelines using age and family history alone. Primary care, as a far-reaching point of healthcare and r
Externí odkaz:
https://doaj.org/article/86c060b81f644ce49806640a6a8109ac
Autor:
Sowmya Jonnagadla, Sharelle L. Joseland, Sibel Saya, Nicole den Elzen, Joanne Isbister, Ingrid M. Winship, Daniel D. Buchanan
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background A suspected Lynch syndrome (SLS) diagnosis is made when a tumor exhibits DNA mismatch repair deficiency but cannot be definitively assigned to an inherited or non-inherited etiology. This diagnosis poses challenges for healthcare
Externí odkaz:
https://doaj.org/article/d865cc6207444ab1a3a498c7336b9a40
Autor:
Shakira Milton, Jon D. Emery, Jane Rinaldi, Joanne Kinder, Adrian Bickerstaffe, Sibel Saya, Mark A. Jenkins, Jennifer McIntosh
Publikováno v:
Implementation Science, Vol 17, Iss 1, Pp 1-14 (2022)
Abstract Background We developed a colorectal cancer risk prediction tool (‘CRISP’) to provide individualised risk-based advice for colorectal cancer screening. Using known environmental, behavioural, and familial risk factors, CRISP was designed
Externí odkaz:
https://doaj.org/article/6d05052641964c98aac7a42875175aa8
Autor:
Nicole den Elzen, Sharelle L. Joseland, Sibel Saya, Sowmya Jonnagadla, Joanne Isbister, Ingrid Winship, Daniel D. Buchanan
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background A diagnosis of suspected Lynch syndrome (SLS) is given when a tumour displays characteristics consistent with Lynch syndrome (LS), but no germline pathogenic variant is identified. This inconclusive diagnosis results in uncertaint
Externí odkaz:
https://doaj.org/article/24df1bd38ed44ff2ad42d8057001c406
Autor:
Shakira Milton, Jennifer McIntosh, Finlay Macrae, Patty Chondros, Lyndal Trevena, Mark Jenkins, Fiona M. Walter, Natalie Taylor, Lucy Boyd, Sibel Saya, Napin Karnchanachari, Kitty Novy, Carmody Forbes, Javiera Martinez Gutierrez, Kate Broun, Sara Whitburn, Sarah McGill, George Fishman, Julie Marker, Max Shub, Jon Emery
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-17 (2021)
Abstract Background Australian guidelines recommend that all people aged 50–70 years old actively consider taking daily low-dose aspirin (100–300 mg per day) for 2.5 to 5 years to reduce their risk of colorectal cancer (CRC). Despite the change o
Externí odkaz:
https://doaj.org/article/54ce9df1c66d4f599f88aa74eaf2813a
Autor:
Anne M. McIntosh, K. Meng Tan, Tahir M. Hakami, Mark R. Newton, Patrick W. Carney, Mengjiazhi Yang, Sibel Saya, David J. T. Marco, Piero Perucca, Patrick Kwan, Terence J. O’Brien, Samuel F. Berkovic
Publikováno v:
Epilepsia Open, Vol 6, Iss 1, Pp 171-180 (2021)
Abstract Objective ‘First seizure’ clinics (FSCs) aim to achieve early expert assessment for individuals with possible new‐onset epilepsy. These clinics also have substantial potential for research into epilepsy evolution, outcomes, and costs.
Externí odkaz:
https://doaj.org/article/d72db5973ccd4527b90eff24c5d0ed46
Autor:
Jennifer G. Walker, Finlay Macrae, Ingrid Winship, Jasmeen Oberoi, Sibel Saya, Shakira Milton, Adrian Bickerstaffe, James G. Dowty, Richard De Abreu Lourenço, Malcolm Clark, Louise Galloway, George Fishman, Fiona M. Walter, Louisa Flander, Patty Chondros, Driss Ait Ouakrim, Marie Pirotta, Lyndal Trevena, Mark A. Jenkins, Jon D. Emery
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-14 (2018)
Abstract Background Australia and New Zealand have the highest incidence rates of colorectal cancer worldwide. In Australia there is significant unwarranted variation in colorectal cancer screening due to low uptake of the immunochemical faecal occul
Externí odkaz:
https://doaj.org/article/ffab5e01939b4371805da3940f480686
Publikováno v:
Genetics in Medicine. 24:2144-2154
PURPOSE: There is significant interest in the use of polygenic risk score (PRS) tests to improve cancer risk assessment and stratified prevention. Our current understanding of preferences regarding different aspects of this novel testing approach is