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pro vyhledávání: '"Siaw L. Chan"'
Autor:
William S. Twadell, Ling Cai, Edward So, Scott E. Strome, Xiaoyu Zhang, Dan H. Schulze, David S. Block, Bhawna Poonia, Erin Burch, Ajay N. Jain, Emmanuel Y. Mérigeon, Henrik S. Olsen, Nader Hanna, Harris G. Yfantis, Ravi Vyzasatya, Siaw L. Chan
Publikováno v:
European Journal of Cancer. 49:3344-3352
Tumour antigen targeted antibodies (mAbs) can induce natural killer (NK) cells to kill tumours through antibody dependent cellular cytotoxicity (ADCC) upon engagement of NK cell expressed FcγRIIIa. FcγRIIIa polymorphisms partially dictate the poten
Autor:
Scott E. Strome, Eduardo Davila, Siaw L. Chan, Dan H. Schulze, Edward So, Lepakshi Sahni, Xiaoyu Zhang, Ajay N. Jain, Michelle A. Sallin
Publikováno v:
Journal of immunological methods. 394(1-2)
In vitro assessment of lymphocyte and natural killer (NK) cell cytotoxicity typically employs density gradient centrifugation and magnetic cell separation to isolate effector cells, and chromium release to assess cytotoxicity. In order to improve the