Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Siavoush Dastmalchi"'
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35032- (2024)
The uremic toxin indoxyl sulfate (IS) has been related to the development of various medical conditions notably chronic kidney disease (CKD). Hence, quantification of this biomarker in biological fluids may be a diagnostic tool to evaluate renal syst
Externí odkaz:
https://doaj.org/article/91109f29be69498eb0294b9455424570
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-11 (2024)
Abstract A rapid and efficient analytical method was established to quantify indoxyl sulfate (IS) in plasma through extraction technique with a deep eutectic solvent (DES) and spectrofluorimetric method. DES (choline chloride: urea) was mixed with pl
Externí odkaz:
https://doaj.org/article/b6d7bf18aaed41b987048514d4397be2
Autor:
Mohammad Maboudian, Elham Amjad, Solmaz Asnaashari, Siavoush Dastmalchi, Babak Sokouti, Yousef Javadzadeh
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background According to the increasing trend of COPD, the timely diagnosis and treatment of the disease can reduce the high costs to the health systems. Therefore, by biological calculation methods, signaling pathways and genes involved in t
Externí odkaz:
https://doaj.org/article/b6b4df5f4f1a426a894898c8e27247fe
Autor:
Mohammad Sadegh Gholami Farashah, Maryam Javadi, Jafar Soleimani Rad, Seyed Kazem Shakouri, Solmaz Asnaashari, Siavoush Dastmalchi, Sadeneh Nikzad, Leila Roshangar
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 13, Iss 4, Pp 736-746 (2023)
Purpose: Exosomes are natural nanoparticles that participate in intercellular communication through molecular transport. Recently, due to their membrane vesicular structure and surface proteins, exosomes have been used extensively in the research fie
Externí odkaz:
https://doaj.org/article/68061747a44d4e519e89e51adf222123
Autor:
Mahrokh Dastmalchi, Mahdiyeh Alizadeh, Omid Jamshidi-Kandjan, Hassan Rezazadeh, Maryam Hamzeh-Mivehroud, Mohammad M Farajollahi, Siavoush Dastmalchi
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 13, Iss 4, Pp 827-836 (2023)
Purpose: Medical usage of L-asparaginase (ASNase), the first-line of acute lymphoblastic leukemia treatment, is linked to allergic responses and toxicities, which necessitates the development of new bio-better ASNases. The aim of the current study wa
Externí odkaz:
https://doaj.org/article/05fd70531de1447b9da55d94f4e606db
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 13, Iss 3, Pp 592-600 (2023)
Purpose: Teduglutide is the first and only FDA-approved drug for long-term treatment of short bowel syndrome (SBS). The current study aimed to present an approach for production of teduglutide using recombinant DNA technology. Methods: The coding gen
Externí odkaz:
https://doaj.org/article/55ae25c3538d41cbb7d4172498f7ec70
Publikováno v:
BioImpacts, Vol 14, Iss 2, Pp 29955-29955 (2024)
Introduction: Non-steroidal anti-inflammatory drugs (NSAIDs) constitute an important class of pharmaceuticals acting on cyclooxygenase COX-1 and COX-2 enzymes. Due to their numerous severe side effects, it is necessary to search for new selective, sa
Externí odkaz:
https://doaj.org/article/0dad4575b1f1477a9717536f83190b2a
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 13, Iss 1, Pp 113-122 (2023)
Purpose: Drug repurposing is an approach successfully used for discovery of new therapeutic applications for the existing drugs. The current study was aimed to use the combination of in silico methods to identify FDA-approved drugs with possible S1P1
Externí odkaz:
https://doaj.org/article/743caefec7434564ab5f815580101d8d
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 12, Iss 4, Pp 818-827 (2022)
Purpose: Today, the discovery of novel and effective chemotherapeutic compounds is the mainchallenge in cancer therapy. In recent years, the anti-tumoral activity of natural naphthoquinonejuglone (JUG), present in different parts of walnut trees, has
Externí odkaz:
https://doaj.org/article/ce7d0caee97d4a539ea5f96a8f637523
Autor:
Ali Akbar Alizadeh, Mona Roshani, Omid Jamshidi Kandjani, Milad Soltani-Saif, Siavoush Dastmalchi
Publikováno v:
Pharmaceutical Sciences, Vol 28, Iss 3, Pp 405-413 (2022)
Background: Fibroblast growth factors (FGFs) are involved in angiogenesis, wound healing and embryonic development. However, one of the causes of cancer cell growth in fibroblast-dependent cancers is FGF7 secreted by fibroblasts. Therefore, antibodie
Externí odkaz:
https://doaj.org/article/877d9b9844db4cdd97709fa20f0cf3c9