Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Siarhei Kirko"'
Autor:
Ilya Zavodnik, Vyacheslav Buko, Oxana Lukivskaya, Elena Lapshina, Tatsiana Ilyich, Elena Belonovskaya, Siarhei Kirko, Elena Naruta, Irina Kuzmitskaya, Grazyna Budryn, Dorota Zyzelevicz, Joanna Orach, Agnieszka Zakrzeska, Lyudmila Kiryukhina
Publikováno v:
Journal of Functional Foods, Vol 57, Iss , Pp 83-94 (2019)
Alcoholic steatohepatitis is an important medical problem but its effective therapies are still not available. Plant polyphenols are widely used for prevention of toxic liver damages. The aim of the study was to evaluate the hepatoprotective mechanis
Externí odkaz:
https://doaj.org/article/6f28c5c61f0e425a8c54a1465b11261b
Autor:
Torsten Diesinger, Alfred Lautwein, Vyacheslav Buko, Elena Belonovskaya, Oksana Lukivskaya, Elena Naruta, Siarhei Kirko, Viktor Andreev, Radovan Dvorsky, Dominik Buckert, Sebastian Bergler, Christian Renz, Dieter Müller‐Enoch, Thomas Wirth, Thomas Haehner
Publikováno v:
Physiological Reports, Vol 9, Iss 6, Pp n/a-n/a (2021)
Abstract Cytochrome P450 2E1 (CYP2E1)‐associated reactive oxygen species production plays an important role in the development and progression of inflammatory liver diseases such as alcoholic steatohepatitis. We developed two new inhibitors for thi
Externí odkaz:
https://doaj.org/article/7650c6afdea94e30a21387f69ebfb9bd
Autor:
Torsten Diesinger, Alfred Lautwein, Sebastian Bergler, Dominik Buckert, Christian Renz, Radovan Dvorsky, Vyacheslav Buko, Siarhei Kirko, Edith Schneider, Florian Kuchenbauer, Mukesh Kumar, Cagatay Günes, Felicitas Genze, Berthold Büchele, Thomas Simmet, Martin Haslbeck, Kai Masur, Thomas Barth, Dieter Müller-Enoch, Thomas Wirth, Thomas Haehner
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 2021 (2021)
Cytochrome P450 2E1 (CYP2E1) is a key target protein in the development of alcoholic and nonalcoholic fatty liver disease (FLD). The pathophysiological correlate is the massive production of reactive oxygen species. The role of CYP2E1 in the developm
Externí odkaz:
https://doaj.org/article/e74a70f467514028b4d33139a1dbe072
Autor:
Torsten Diesinger, Vyacheslav Buko, Alfred Lautwein, Radovan Dvorsky, Elena Belonovskaya, Oksana Lukivskaya, Elena Naruta, Siarhei Kirko, Viktor Andreev, Dominik Buckert, Sebastian Bergler, Christian Renz, Edith Schneider, Florian Kuchenbauer, Mukesh Kumar, Cagatay Günes, Berthold Büchele, Thomas Simmet, Dieter Müller-Enoch, Thomas Wirth, Thomas Haehner
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0235990 (2020)
Background and aimsAlcoholic steatohepatitis (ASH)-the inflammation of fatty liver-is caused by chronic alcohol consumption and represents one of the leading chronic liver diseases in Western Countries. ASH can lead to organ dysfunction or progress t
Externí odkaz:
https://doaj.org/article/67889073cb194f45b24f6833841d8c81
Autor:
Kateryna Goncharova, Siarhei Kirko, Danica Grujic, Marek Kardas, Elżbieta Grochowska-Niedworok, Olena Prykhodko, Jarosław Woliński, Galyna Ushakova, Liudmyla Lozinska, Stefan G. Pierzynowski
Publikováno v:
Journal of Functional Foods, Vol 34, Iss , Pp 422-430 (2017)
An exocrine pancreatic insufficient (EPI) pig model was used in the study. The effects of milk formula pre-digestion with immobilized microbial lipase, on the absorption and tissue accretion of long chain polyunsaturated fatty acids (LCPUFA) were ass
Externí odkaz:
https://doaj.org/article/c18cdbfa3a5e4d02b1119cf3dccfeecc
Autor:
Grażyna Budryn, Siarhei Kirko, T. V. Ilyich, Dorota Zyzelevicz, Lyudmila Kiryukhina, Agnieszka Zakrzeska, Vyacheslav Buko, Oxana Lukivskaya, Joanna Orach, Elena A. Lapshina, Elena Naruta, Elena Belonovskaya, Irina Kuzmitskaya, Ilya B. Zavodnik
Publikováno v:
Journal of Functional Foods, Vol 57, Iss, Pp 83-94 (2019)
Alcoholic steatohepatitis is an important medical problem but its effective therapies are still not available. Plant polyphenols are widely used for prevention of toxic liver damages. The aim of the study was to evaluate the hepatoprotective mechanis
Autor:
Elena Belonovskaya, Dominik Buckert, Siarhei Kirko, Oksana Lukivskaya, Christian Renz, Viktor Andreev, Sebastian Bergler, Vyacheslav Buko, Thomas Wirth, Radovan Dvorsky, Thomas Haehner, Torsten Diesinger, Alfred Lautwein, Dieter Müller-Enoch, Elena Naruta
Publikováno v:
Physiological Reports
Physiological Reports, Vol 9, Iss 6, Pp n/a-n/a (2021)
Physiological Reports, Vol 9, Iss 6, Pp n/a-n/a (2021)
Cytochrome P450 2E1 (CYP2E1)‐associated reactive oxygen species production plays an important role in the development and progression of inflammatory liver diseases such as alcoholic steatohepatitis. We developed two new inhibitors for this isoenzy
Autor:
Florian Kuchenbauer, Felicitas Genze, Cagatay Günes, Thomas Wirth, Vyacheslav Buko, Sebastian Bergler, Christian Renz, Thomas F. E. Barth, Edith Schneider, Siarhei Kirko, Mukesh Kumar, Dominik Buckert, Thomas Simmet, Radovan Dvorsky, Martin Haslbeck, Thomas Haehner, Torsten Diesinger, Kai Masur, Alfred Lautwein, Dieter Müller-Enoch, Berthold Büchele
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 2021 (2021)
Canadian Journal of Gastroenterology & Hepatology
Canadian Journal of Gastroenterology & Hepatology
Cytochrome P450 2E1 (CYP2E1) is a key target protein in the development of alcoholic and nonalcoholic fatty liver disease (FLD). The pathophysiological correlate is the massive production of reactive oxygen species. The role of CYP2E1 in the developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aece6925b01657f18020b2fe74eee71c
https://mediatum.ub.tum.de/1649993
https://mediatum.ub.tum.de/1649993
Autor:
Berthold Büchele, Elena Belonovskaya, Cagatay Günes, Oksana Lukivskaya, Florian Kuchenbauer, Siarhei Kirko, Thomas Wirth, Thomas Simmet, Edith Schneider, Dominik Buckert, Radovan Dvorsky, Alfred Lautwein, Dieter Müller-Enoch, Viktor Andreev, Sebastian Bergler, Vyacheslav Buko, Thomas Haehner, Christian Renz, Torsten Diesinger, Elena Naruta, Mukesh Kumar
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0235990 (2020)
PLoS ONE, Vol 15, Iss 7, p e0235990 (2020)
Background and aimsAlcoholic steatohepatitis (ASH)-the inflammation of fatty liver-is caused by chronic alcohol consumption and represents one of the leading chronic liver diseases in Western Countries. ASH can lead to organ dysfunction or progress t
Autor:
Ilya B. Zavodnik, Dorota Żyżelewicz, Elena Belonovskaya, Valentina Moroz, Małgorzata Zakłos-Szyda, Aliaksei Bakunovich, Grażyna Budryn, Vyacheslav Buko, Agnieszka Zakrzeska, Viktor Rusin, Siarhei Kirko
Publikováno v:
Nutrients, Vol 13, Iss 4155, p 4155 (2021)
Nutrients
Volume 13
Issue 11
Nutrients
Volume 13
Issue 11
The aim of this study was to evaluate the therapeutic effects of chlorogenic acid (CGA) in rats with advanced alcoholic steatohepatitis. The rats were fed on a high-fat diet and gavaged with ethanol (4 g/kg) for 8 weeks. The livers of ethanol-treated