Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sianna Castillo"'
Publikováno v:
In Drug Resistance Updates 2002 5(6):234-248
Autor:
Florence Lorget, Sean M. Bell, Mika Aoyagi-Scharber, Sianna Castillo, William R. Wilcox, Pavel Krejci, Melita Dvorak-Ewell, David L. Rimoin, Jeff Peng, Charles A. O’Neill, Stuart Bunting, Daniel J. Wendt, Sherry Bullens
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 353:132-149
Achondroplasia (ACH), the most common form of human dwarfism, is caused by an activating autosomal dominant mutation in the fibroblast growth factor receptor-3 gene. Genetic overexpression of C-type natriuretic peptide (CNP), a positive regulator of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::754c5c256ff0cb2abb4eb6148f359496
https://doi.org/10.1124/jpet.114.218560
https://doi.org/10.1124/jpet.114.218560
Autor:
Simone Filosto, Sianna Castillo, Aaron Danielson, Lisa Franzi, Elaine Khan, Nick Kenyon, Jerold Last, Kent Pinkerton, Rubin Tuder, Tzipora Goldkorn
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 44:350-360
Chronic obstructive pulmonary disease (COPD) is caused by exposure to cigarette smoke (CS). One mechanism of CS-induced lung injury is aberrant generation of ceramide, which leads to elevated apoptosis of epithelial and endothelial cells in the alveo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fea11c332e8e959b6ab1bf46a452c0e
https://doi.org/10.1165/rcmb.2009-0422oc
https://doi.org/10.1165/rcmb.2009-0422oc
Publikováno v:
Experimental Cell Research. 313:2680-2686
Airway epithelial cells are constantly exposed to environmental insults such as air pollution or tobacco smoke that may contain high levels of reactive nitrogen and reactive oxygen species. Previous work from our laboratory demonstrated that the reac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1676c18f10973df910b4ea71dcddf233
https://doi.org/10.1016/j.yexcr.2007.04.002
https://doi.org/10.1016/j.yexcr.2007.04.002
Autor:
Jyoti Thaikoottathil, Elaine M. Khan, Michal Levy, S. Sianna Castillo, Chunbo Wang, Tzipora Goldkorn
Publikováno v:
Experimental Cell Research. 313:816-823
Reactive nitrogen species (RNS) are implicated in the pathophysiology of inflammatory lung diseases such as asthma and chronic obstructive pulmonary disease. The molecular mechanisms and signaling events involved in lung cell injury by RNS are still
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da0315979c1c8f752213c78b64239f1
https://doi.org/10.1016/j.yexcr.2006.12.001
https://doi.org/10.1016/j.yexcr.2006.12.001
Autor:
Pavel A. Petukhov, Kip A. West, Courtney A. Granville, Junji Tsurutani, Phillip A. Dennis, John Brognard, Chunyu Zhang, Alan P. Kozikowski, Min Li, S. Sianna Castillo, Joell G. Gills, Michael Jung
Publikováno v:
Cancer Research. 64:2782-2792
Activation of the PI3k/Akt pathway controls key cellular processes and contributes to tumorigenesis in vivo, but investigation of the PI3k/Akt pathway has been limited by the lack of specific inhibitors directed against Akt. To develop Akt inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df1b13b6d0288a3700a1e8d09d8b2ec
https://doi.org/10.1158/0008-5472.can-03-1530
https://doi.org/10.1158/0008-5472.can-03-1530
Autor:
Dorothy Teegarden, S. Sianna Castillo
Publikováno v:
The Journal of Nutrition. 133:3343-3349
The roles of extracellular regulated kinase (ERK) activation and mitogen-activated protein kinase phosphatase-1 (MKP-1) were examined in sphingosine-1-phosphate (S1P)-mediated inhibition of apoptosis in C3H10T 1/2 fibroblast cells. Apoptosis induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac7ca849d91bafb73cbbd226f7143703
https://doi.org/10.1093/jn/133.11.3343
https://doi.org/10.1093/jn/133.11.3343
Autor:
Nicholas P. Restifo, Samuel T Hwang, Takashi Murakami, Adela R. Cardones, Steven E. Finkelstein, Frank O. Nestle, Brenda A. Klaunberg, Phillip A. Dennis, S. Sianna Castillo
Publikováno v:
The Journal of Experimental Medicine
Human melanoma cells frequently express CC chemokine receptor (CCR)10, a receptor whose ligand (CCL27) is constitutively produced by keratinocytes. Compared with B16 murine melanoma, cells rendered more immunogenic via overexpression of luciferase, B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::118ccaf4ad4c1ddfa1527d950e0a5c53
http://europepmc.org/articles/PMC2194242
http://europepmc.org/articles/PMC2194242
Publikováno v:
Drug Resistance Updates. 5:234-248
The resistance of many types of cancer to conventional chemotherapies is a major factor undermining successful cancer treatment. In this review, the role of a signal transduction pathway comprised of the lipid kinase, phosphatidylinositol 3-kinase (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f499dd5371a07a2d896ca7c5995498
https://doi.org/10.1016/s1368-7646(02)00120-6
https://doi.org/10.1016/s1368-7646(02)00120-6
Autor:
Simone Filosto, Sianna Castillo, Aaron Danielson, Lisa Franzi, Elaine Khan, Jerold Last, Kent E. Pinkerton, Nick Kenyon, Rubin Tuder, Tzipora Goldkorn
Publikováno v:
B37. CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATHOGENESIS I.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2a4c8c0da8e8c57fadb9f7e45a5410a
https://doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a2889
https://doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a2889