Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Siani Weston"'
Autor:
Peter G. Hendrickson, Michael Olson, Tim Luetkens, Siani Weston, Tiffany Han, Djordje Atanackovic, Gabriel C. Fine
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Hepatocellular Carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide. Current systemic therapies result only in modest benefits and new therapeutic options are critically needed. Some patients show promising clinical resp
Externí odkaz:
https://doaj.org/article/18f38c4ce3534d328143bb3ffa9cf47c
Autor:
Fiorella Iglesias, Siani Weston, Stephanie V. Avila, Holly Zhou, Sara Yousef, Mark Fluchel, Erin Morales, Michael L. Olsen, Sabarinath V. Radhakrishnan, Tim Luetkens
Downregulation of HLA is one of the most common tumor escape mechanisms by enabling tumors to persist in the presence of tumor-reactive T cells. HLA loss is particularly common in children with high-risk neuroblastoma, who have a 50% long-term surviv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99ed732e2ce70f7a8be974779d195f19
https://doi.org/10.1101/2022.06.21.496901
https://doi.org/10.1101/2022.06.21.496901
Autor:
Michael Olson, Tim Luetkens, Peter G. Hendrickson, Gabriel C. Fine, Djordje Atanackovic, Tiffany Han, Siani Weston
Publikováno v:
Oncoimmunology
OncoImmunology, Vol 9, Iss 1 (2020)
OncoImmunology, Vol 9, Iss 1 (2020)
Hepatocellular Carcinoma (HCC) is one of the leading causes of cancer-related mortality worldwide. Current systemic therapies result only in modest benefits and new therapeutic options are critically needed. Some patients show promising clinical resp
Publikováno v:
Cancer Research. 80:2171-2171
Background: In principle, T cells can target cancer cells by recognizing tumor-specific peptides presented by HLA proteins. HLA downregulation is one of the most common immune escape mechanisms and frequently observed in patients with high-risk neuro