Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sian-Marie O'Brien"'
Autor:
Andrew P Holmes, Ting Y Yu, Samantha Tull, Fahima Syeda, Stefan M Kuhlmann, Sian-Marie O'Brien, Pushpa Patel, Keith L Brain, Davor Pavlovic, Nigel A Brown, Larissa Fabritz, Paulus Kirchhof
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154077 (2016)
BackgroundThe left atrial posterior wall (LAPW) is potentially an important area for the development and maintenance of atrial fibrillation. We assessed whether there are regional electrical differences throughout the murine left atrial myocardium th
Externí odkaz:
https://doaj.org/article/fb2c0df40e77457cb0987ba54a3db1b9
Autor:
Paulus Kirchhof, Andrew P. Holmes, Larissa Fabritz, Maddalena Tessari, Giuseppe Faggian, Davor Pavlovic, Daniel M. Johnson, Sian-Marie O’Brien
Publikováno v:
Biophysical Journal. 118:577a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a42e6b6eaa2d005b37c415a7ce3a46bc
https://doi.org/10.1016/j.bpj.2019.11.3135
https://doi.org/10.1016/j.bpj.2019.11.3135
Autor:
Davor Pavlovic, Nashitha Kabir, Paulus Kirchhof, Dannie Fobian, Clara Apicella, Sian-Marie O’Brien, Larissa Fabritz, Andrew P. Holmes
Publikováno v:
Basic Science.
Background Atrial fibrillation (AF) is the most common cardiac arrhythmia and is prevalent in 3% of the population. AF is a major driver of stroke, heart failure, unplanned hospitalisations and death. Despite the increasing use of catheter ablation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccd093ce117cdbfb4c29572d1bb8ef98
https://doi.org/10.1136/heartjnl-2018-bcs.100
https://doi.org/10.1136/heartjnl-2018-bcs.100
133 Langendorff-free method for isolation of cardiomyocytes from the adult and neonatal mouse hearts
Autor:
Paulus Kirchhof, Davor Pavlovic, Tuan Luu, Andrew P. Holmes, Yiqing Li, Claire Hepburn, Roger Foo, Sian-Marie O’Brien, Larissa Fabritz, Matthew Ackers-Johnson
Publikováno v:
Basic Science.
Rationale Isolation of high quality myocytes from the adult mouse heart has traditionally required Langendorff perfusion systems, involving a high degree of technical skill. We recently introduced a simplified Langendorff-free protocol, utilising dir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41fb4a2b691f5babe04180bcec902903
https://doi.org/10.1136/heartjnl-2018-bcs.130
https://doi.org/10.1136/heartjnl-2018-bcs.130
Autor:
Peter Yiqing Li, Davor Pavlovic, Sian-Marie O’Brien, Roger Foo, Andrew P. Holmes, Matthew Ackers-Johnson
Publikováno v:
Circulation research. 119(8)
Rationale: Cardiovascular disease represents a global pandemic. The advent of and recent advances in mouse genomics, epigenomics, and transgenics offer ever-greater potential for powerful avenues of research. However, progress is often constrained by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9792393cc25f7385c997b3eaa5ec4491
https://pubmed.ncbi.nlm.nih.gov/27688302
https://pubmed.ncbi.nlm.nih.gov/27688302
Autor:
Andrew B. Holmes, Larissa Fabritz, Paulus Kirchhof, Clara Apicella, Sian-Marie O’Brien, Davor Pavlovic, Geroge Parnell
Publikováno v:
Heart. 103:A143.3-A144
Introduction Several antiarrhythmic drugs target the cardiac sodium current INA. There is an increasing interest in atrial-specific ion channel inhibition, e.g. to allow selective antiarrhythmic drug development for the treatment of atrial fibrillati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76d160cf8c69bd1f795642a4836e6566
https://doi.org/10.1136/heartjnl-2017-311726.219
https://doi.org/10.1136/heartjnl-2017-311726.219