Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Sian Rizzo"'
Autor:
David Bernard, Juan F. Martinez-Leal, Sian Rizzo, Dolores Martinez, David Hudson, Tapio Visakorpi, Gordon Peters, Amancio Carnero, David Beach, Jesus Gil
Publikováno v:
Oncogene. 41:4980-4980
Publikováno v:
Toxicologic Pathology. 37:170-174
In vitro techniques for the culture of hemopoietic stem cells and committed hemopoietic progenitor cells in rat bone marrow have not been adequately described in the literature. In the present investigations, and using commercially available hemopoie
Autor:
Sian Rizzo, Andrew M. Pilling, John Turton, William Sones, Charles M Andrews, Thomas C. Williams, Gemma Molyneux, Frances M. Gibson, Edward C. Gordon-Smith
Publikováno v:
International Journal of Experimental Pathology. 87:49-63
Aplastic anaemia (AA) in man is an often fatal disease characterized by pancytopenia of the peripheral blood and aplasia of the bone marrow. AA is a toxic effect of many drugs and chemicals (e.g. chloramphenicol, azathioprine, phenylbutazone, gold sa
Autor:
Sian Rizzo, Edward C. Gordon-Smith, Kai Chiu Liu, Susan Sulsh, Frances M. Gibson, Andrew M. Pilling, Gemma Molyneux, John Turton
Publikováno v:
International Journal of Experimental Pathology. 86:415-430
Mitomycin (MMC), like many antineoplastic drugs, induces a predictable, dose-related, bone marrow depression in man and laboratory animals; this change is generally reversible. However, there is evidence that MMC may also cause a late-stage or residu
Autor:
Judith C. W. Marsh, Modupe O. Elebute, Edward C. Gordon-Smith, Jennifer A. Tooze, Frances M. Gibson, Sian Rizzo
Publikováno v:
British Journal of Haematology. 123:552-560
Summary. Paroxysmal nocturnal haemoglobinuria (PNH) is an acquired clonal disorder of the haemopoietic stem cell (HSC). The pathogenetic link with bone marrow failure is well recognized; however, the process of clonal expansion of the glycosylphospha
Autor:
Theodora R. Rutherford, Julie Flynn, Theodora Foukaneli, Jonathan P. Welsh, Edward C. Gordon-Smith, Matthew Murphy, Sian Rizzo, Katherine Rice, Charlotte V. Cox, Frances M. Gibson
Publikováno v:
British Journal of Haematology. 122:289-297
Summary. Antithymocyte globulin (ATG) is widely used in the treatment of aplastic anaemia (AA) and a response occurs in 60–80% of patients. However, its exact mechanism of action in the treatment of AA has yet to be determined. Previously, we have
Autor:
Edward C. Gordon-Smith, Thomas C. Williams, John Turton, Frances M. Gibson, George Macharia, Paraskevi Diamanti, Sian Rizzo, C Michael Andrews
Publikováno v:
International Journal of Experimental Pathology. 84:31-48
Aplastic anaemia (AA) is characterized by hypocellular marrow, pancytopenia, and risk of severe anaemia, haemorrhage and infection. AA is often idiopathic, but frequently occurs after exposure to drugs/chemicals. However, the pathogenesis of AA is no
Autor:
John Scopes, Modupe O. Elebute, Frances M. Gibson, Edward C. Gordon-Smith, Sian Rizzo, Helen A. Papadaki
Publikováno v:
The Hematology Journal. 3:230-236
Aplastic anemia is associated with quantitative and functional abnormalities in the hematopoietic stem cell compartment. Currently, one of the most primitive human hematopoietic progenitor cells that can be functionally assayed in vitro is the long-t
Publikováno v:
Blood. 96:3272-3275
To investigate whether bone marrow (BM) stem cell compartment and/or BM microenvironment are affected by the immune insult in autoimmune cytopenias (AICs), BM stem cell reserve and function and BM stromal function were studied in 15 AIC patients. Ste
Autor:
Gerhardt, Attard, Sian, Rizzo, Ioanna, Ledaki, Jeremy, Clark, Alison H M, Reid, Alan, Thompson, Vincent, Khoo, Johann S, de Bono, Colin S, Cooper, David L, Hudson
Publikováno v:
The Prostate. 69(14)
New in vitro models of castration-resistant prostate cancer (CRPC) are urgently required.Trans-rectal needle biopsies (TRBP) of the prostate were performed for research purposes on progressing CRPC patients who had not received prior treatment to the