Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sian Lowri Griffiths"'
Autor:
Rachel Upthegrove, Roisin Mooney, Paul McCrone, Kamaldeep Bhui, Nimra Khan, Dawn Edge, Peter A Coventry, Michael Larkin, Doreen Joseph, Jason Arday, Sian Lowri Griffiths, Tara Morrey, Uzma Zahid, Tanya Mackay, Frank Keating, Georgina M Hosang
Publikováno v:
BMJ Open, Vol 14, Iss 2 (2024)
Introduction Ethnic minorities (also called racialised groups) are more likely to experience severe mental illness (SMI). People with SMI are more likely to experience multimorbidity (MM), making psychosis among racialised groups more likely to lead
Externí odkaz:
https://doaj.org/article/0a39268d650d4bc9bde2236f9bd9faa1
Autor:
Stephen Burgess, Peter Jones, Rachel Upthegrove, Carmine Pariante, Graham K Murray, Anthony David, Martin Wilson, Nicholas Barnes, Paola Dazzan, John Suckling, Valeria Mondelli, Muzaffer Kaser, Neil Harrison, Georgios Gkoutos, Golam M Khandaker, Deepak Jadon, James MacCabe, Gary Donohoe, Alice Egerton, Bill Deakin, Jack Rogers, Éimear M Foley, Sian Lowri Griffiths, Alexander Murray, Fabiana Corsi-Zuelli, Hannah Hickinbotham, Ella Warwick, Nicholas M Barnes, Golam Khandaker, David Cotter, Ed Bullmore, Eva Meisenzahl, Joanna Neill, Nikos Koutsouleris, Stephen Wood
Publikováno v:
BMJ Open, Vol 13, Iss 3 (2023)
Introduction Evidence suggests a potentially causal role of interleukin 6 (IL-6), a pleiotropic cytokine that generally promotes inflammation, in the pathogenesis of psychosis. However, no interventional studies in patients with psychosis, stratified
Externí odkaz:
https://doaj.org/article/68df20bff4534eeebe80122791e23057
Autor:
Shalaila S. Haas, Raimo K. R. Salokangas, Stephan Ruhrmann, Stephen J. Wood, Katharine Chisholm, Peter Falkai, Paolo Brambilla, Christos Pantelis, Julian Wenzel, Theresa Lichtenstein, Frauke Schultze-Lutter, Sian Lowri Griffiths, Nikolaos Koutsouleris, Anne Ruef, Paris Alexandros Lalousis, Joseph Kambeitz, Dominic B. Dwyer, Linda A. Antonucci, Marlene Rosen, Alessandro Pigoni, Oemer Faruk Oeztuerk, Rachel Upthegrove, Stefan Borgwardt, David Popovic, Eva Meisenzahl, Peter F. Liddle, Lana Kambeitz-Ilankovic
Publikováno v:
European Archives of Psychiatry and Clinical Neuroscience. 272:403-413
Background Formal thought disorder (FTD) has been associated with more severe illness courses and functional deficits in patients with psychotic disorders. However, it remains unclear whether the presence of FTD characterises a specific subgroup of p
Publikováno v:
BJPsych Bulletin. 46:83-89
Aims and methodDepression in first-episode psychosis (FEP) is highly prevalent and associated with poor outcomes; it has become increasingly recognised and adopted in national and international guidelines for psychosis. Using a 26-item questionnaire,
Autor:
Éimear M Foley, Sian Lowri Griffiths, Alexander Murray, Jack Rogers, Fabiana Corsi-Zuelli, Hannah Hickinbotham, Ella Warwick, Martin Wilson, Muzaffer Kaser, Graham K Murray, Bill Deakin, Deepak Jadon, John Suckling, Nicholas M Barnes, Rachel Upthegrove, Golam M Khandaker
Publikováno v:
BMJ Open. 13:e067944
IntroductionEvidence suggests a potentially causal role of interleukin 6 (IL-6), a pleiotropic cytokine that generally promotes inflammation, in the pathogenesis of psychosis. However, no interventional studies in patients with psychosis, stratified
Autor:
David Popovic, Anne Ruef, Dominic B. Dwyer, Linda A. Antonucci, Julia Eder, Rachele Sanfelici, Lana Kambeitz-Ilankovic, Omer Faruk Oztuerk, Mark S. Dong, Riya Paul, Marco Paolini, Dennis Hedderich, Theresa Haidl, Joseph Kambeitz, Stephan Ruhrmann, Katharine Chisholm, Frauke Schultze-Lutter, Peter Falkai, Giulio Pergola, Giuseppe Blasi, Alessandro Bertolino, Rebekka Lencer, Udo Dannlowski, Rachel Upthegrove, Raimo K.R. Salokangas, Christos Pantelis, Eva Meisenzahl, Stephen J. Wood, Paolo Brambilla, Stefan Borgwardt, Nikolaos Koutsouleris, Mark Sen Dong, Anne Erkens, Eva Gussmann, Shalaila Haas, Alkomiet Hasan, Claudius Hoff, Ifrah Khanyaree, Aylin Melo, Susanna Muckenhuber-Sternbauer, Janis Köhler, Ömer Faruk Öztürk, Nora Penzel, Adrian Rangnick, Sebastian von Saldern, Moritz Spangemacher, Ana Tupac, Maria Fernanda Urquijo, Johanna Weiske, Julian Wenzel, Antonia Wosgien, Linda Betz, Karsten Blume, Mauro Seves, Nathalie Kaiser, Thorsten Lichtenstein, Christiane Woopen, Christina Andreou, Laura Egloff, Fabienne Harrisberger, Claudia Lenz, Letizia Leanza, Amatya Mackintosh, Renata Smieskova, Erich Studerus, Anna Walter, Sonja Widmayer, Chris Day, Sian Lowri Griffiths, Mariam Iqbal, Mirabel Pelton, Pavan Mallikarjun, Alexandra Stainton, Ashleigh Lin, Alexander Denissoff, Anu Ellilä, Tiina From, Markus Heinimaa, Tuula Ilonen, Päivi Jalo, Heikki Laurikainen, Maarit Lehtinen, Antti Luutonen, Akseli Mäkela, Janina Paju, Henri Pesonen, Reetta-Liina Armio (Säilä, Elina Sormunen, Anna Toivonen, Otto Turtonen, Ana Beatriz Solana, Manuela Abraham, Nicolas Hehn, Timo Schirmer, Carlo Altamura, Marika Belleri, Francesca Bottinelli, Adele Ferro, Marta Re, Emiliano Monzani, Mauro Percudani, Maurizio Sberna, Armando D’Agostino, Lorenzo Del Fabro, Giampaolo Perna, Maria Nobile, Alessandra Alciati, Matteo Balestrieri, Carolina Bonivento, Giuseppe Cabras, Franco Fabbro, Marco Garzitto, Sara Piccin
Publikováno v:
Biological Psychiatry. 88:829-842
Background Childhood trauma (CT) is a major yet elusive psychiatric risk factor, whose multidimensional conceptualization and heterogeneous effects on brain morphology might demand advanced mathematical modeling. Therefore, we present an unsupervised
Publikováno v:
Early Intervention in Psychiatry. 15:993-1001
BACKGROUND: Poor functioning is common in psychosis, with predictors of poor outcome including negative symptoms and deficits in neurocognition (NC) and social cognition (SC). The extent to which these variables contribute unique variance in social a
Autor:
Paris Alexandros Lalousis, Lianne Schmaal, Stephen J. Wood, Renate L.E.P. Reniers, Nicholas M. Barnes, Katharine Chisholm, Sian Lowri Griffiths, Alexandra Stainton, Junhao Wen, Gyujoon Hwang, Christos Davatzikos, Julian Wenzel, Lana Kambeitz-Ilankovic, Christina Andreou, Carolina Bonivento, Udo Dannlowski, Adele Ferro, Theresa Lichtenstein, Anita Riecher-Rössler, Georg Romer, Marlene Rosen, Alessandro Bertolino, Stefan Borgwardt, Paolo Brambilla, Joseph Kambeitz, Rebekka Lencer, Christos Pantelis, Stephan Ruhrmann, Raimo K.R. Salokangas, Frauke Schultze-Lutter, André Schmidt, Eva Meisenzahl, Nikolaos Koutsouleris, Dominic Dwyer, Rachel Upthegrove
Publikováno v:
Lalousis, Paris Alexandros; Schmaal, Lianne; Wood, Stephen J; Reniers, Renate L E P; Barnes, Nicholas M; Chisholm, Katharine; Griffiths, Sian Lowri; Stainton, Alexandra; Wen, Junhao; Hwang, Gyujoon; Davatzikos, Christos; Wenzel, Julian; Kambeitz-Ilankovic, Lana; Andreou, Christina; Bonivento, Carolina; Dannlowski, Udo; Ferro, Adele; Lichtenstein, Theresa; Riecher-Rössler, Anita; Romer, Georg; ... (2022). Neurobiologically Based Stratification of Recent-Onset Depression and Psychosis: Identification of Two Distinct Transdiagnostic Phenotypes. Biological psychiatry, 92(7), pp. 552-562. Elsevier 10.1016/j.biopsych.2022.03.021
BACKGROUND Identifying neurobiologically based transdiagnostic categories of depression and psychosis may elucidate heterogeneity and provide better candidates for predictive modeling. We aimed to identify clusters across patients with recent-onset d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5acbfbee33d5966b2cf3aff0c5f6e729
Autor:
John A, Williams, Stephen, Burgess, John, Suckling, Paris Alexandros, Lalousis, Fatima, Batool, Sian Lowri, Griffiths, Edward, Palmer, Andreas, Karwath, Andrey, Barsky, Georgios V, Gkoutos, Stephen, Wood, Nicholas M, Barnes, Anthony S, David, Gary, Donohoe, Joanna C, Neill, Bill, Deakin, Golam M, Khandaker, Rachel, Upthegrove, Neil, Harrison
Publikováno v:
JAMA Psychiatry. 79:498
Previous in vitro and postmortem research suggests that inflammation may lead to structural brain changes via activation of microglia and/or astrocytic dysfunction in a range of neuropsychiatric disorders.To investigate the relationship between infla
Autor:
Dominic B. Dwyer, Rebekka Lencer, Stefan Borgwardt, Nikolaos Koutsouleris, Sian Lowri Griffiths, Stephen J. Wood, Frauke Schultze-Lutter, Lianne Schmaal, Christos Pantelis, Marlene Rosen, Stephan Ruhrmann, Katharine Chisholm, Rachel Upthegrove, Eva Meisenzahl, Joseph Kambeitz, Theresa Haidl, Alessandro Bertolino, Paris Alexandros Lalousis, Renate L. E. P. Reniers, Paolo Brambilla, Adele Ferro, André Schmidt, Carolina Bonivento, Raimo K. R. Salokangas
Publikováno v:
Schizophr Bull
Diagnostic heterogeneity within and across psychotic and affective disorders challenges accurate treatment selection, particularly in the early stages. Delineation of shared and distinct illness features at the phenotypic and brain levels may inform