Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Siamand Hosseini"'
Autor:
Marcin Dembek, Stephanie E. Willing, Huynh A. Hong, Siamand Hosseini, Paula S. Salgado, Simon M. Cutting
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Clostridium difficile remains a leading nosocomial pathogen, putting considerable strain on the healthcare system. The ability to form endospores, highly resistant to environmental insults, is key to its persistence and transmission. However, importa
Externí odkaz:
https://doaj.org/article/2b9d118fcdb44bff9174da16d6a5353f
Autor:
Jürgen Zentek, Siamand Hosseini, Huynh A. Hong, Saba Anwar, Simon M. Cutting, Anthony J. Wilkinson, William T. Ferreira, Mikhail Soloviev, Krisztina Hitri, Wilfried Vahjen
Publikováno v:
The Journal of Infectious Diseases
Spores of Clostridium difficile carry a chitinase enzyme whose function is to bind to mucin, leading to its degradation. We show in vivo that this is potentially an important element of colonization and virulence.
Clostridium difficile infection
Clostridium difficile infection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701136427ab37f97c7dfd58536afab66
https://eprints.whiterose.ac.uk/128823/1/jix488.pdf
https://eprints.whiterose.ac.uk/128823/1/jix488.pdf
Publikováno v:
Applied and environmental microbiology. 84(3)
Genetic manipulation of bacterial spores of the genus Bacillus has shown potential for vaccination and for delivery of drugs or enzymes. Remarkably, proteins displayed on the spore surface retain activity and generally are not degraded. The heat stab
Autor:
Annie van Broekhoven, Krisztina Hitri, Anthony J. Wilkinson, Jonathan Kearsey, Natalia Kotowicz, Huynh A. Hong, Simon M. Cutting, Siamand Hosseini, Donna Bryan, Fatma Mawas
Publikováno v:
Infection and Immunity. 85
Mucosal immunity is considered important for protection against Clostridium difficile infection (CDI). We show that in hamsters immunized with Bacillus subtilis spores expressing a carboxy-terminal segment (TcdA26–39) of C. difficile toxin A, no co
Autor:
Marcin, Dembek, Stephanie E, Willing, Huynh A, Hong, Siamand, Hosseini, Paula S, Salgado, Simon M, Cutting
Publikováno v:
Frontiers in Microbiology
Clostridium difficile remains a leading nosocomial pathogen, putting considerable strain on the healthcare system. The ability to form endospores, highly resistant to environmental insults, is key to its persistence and transmission. However, importa
Autor:
Fatme Mawas, Simon M. Cutting, Annie van Broekhoven, Anthony J. Wilkinson, Huynh A. Hong, Jonathan Kearsey, Krisztina Hitri, Siamand Hosseini, Natalia Kotowicz, Donna Bryan
Publikováno v:
Infection and immunity. 85(4)
Mucosal immunity is considered important for protection against Clostridium difficile infection (CDI). We show that in hamsters immunized with Bacillus subtilis spores expressing a carboxy-terminal segment (TcdA 26–39 ) of C. difficile toxin A, no