Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Siamak Tabib"'
Autor:
Siamak Tabibzadeh, Olen R. Brown
Publikováno v:
Aging and Cancer, Vol 5, Iss 1-2, Pp 3-13 (2024)
Abstract Ion gradients across cell membranes generate voltage potentials that are involved in a wide range of biological processes. According to the membrane hypothesis of aging, aging is inextricably linked to a decrease in resting membrane potentia
Externí odkaz:
https://doaj.org/article/b669fc08a7ae4a708ddc762889095011
Publikováno v:
American Journal of Gastroenterology. 110:S269-S270
Publikováno v:
Gastrointestinal endoscopy. 60(5)
Autor:
Siamak Tabibzadeh
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 26, Iss 1, Pp 50-96 (2020)
Aging leads to and is associated with aberrant function of multiple signaling pathways and a host of factors that maintain cellular health. Under normal conditions, the prolongevity, 5' AMP-activated protein kinase (AMPK), is dedicated to the homeost
Externí odkaz:
https://doaj.org/article/f8920f29756148e699b97ce8bbfc643a
Autor:
Siamak Tabibzadeh
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 26, Iss 1, Pp 97-162 (2020)
Aging results from aberrations in signaling mechanisms and decline in biologic activities and cellular functions. Anti-aging strategies include a number of dietary, genetic, and pharmacological interventions that converge on a core network of nutrien
Externí odkaz:
https://doaj.org/article/955d8292c8644ae1b396f395b57a2bd9
Autor:
Siamak Tabibzadeh
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 26, Iss 1, Pp 1-49 (2020)
Aging in mammals results in numerous age related pathologies such as diabetes, and Alzheimer’s disease which ultimately lead to organ failure and the demise of the organism. Numerous cell-centric hypotheses have attributed the disorders of aging to
Externí odkaz:
https://doaj.org/article/717a2eafe14a48bc92c5a693475ec4e7
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241685 (2020)
The efficiency of cell reprogramming in two-dimensional (2D) cultures is limited. Given that cellular stemness is intimately related to microenvironmental changes, 3D cell cultures have the potential of overcoming this limited capacity by allowing ce
Externí odkaz:
https://doaj.org/article/700966040cc349ce9522a126e840a96f
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164710 (2016)
Recent evidence suggests that hydrogen sulfide (H2S) has cytoprotective and anti-aging effects. However, the mechanisms for such properties are not fully understood. Here, we show that the expression of the main H2S producing enzyme, CBS, and product
Externí odkaz:
https://doaj.org/article/505f7ba863cd4b29961d8978e459076c
Autor:
Reiko Sanokawa-Akakura, Elena A Ostrakhovitch, Shin Akakura, Scott Goodwin, Siamak Tabibzadeh
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108537 (2014)
We recently demonstrated that cancer cells that recover from damage exhibit increased aerobic glycolysis, however, the molecular mechanism by which cancer cells survive the damage and show increased aerobic glycolysis remains unknown. Here, we demons
Externí odkaz:
https://doaj.org/article/83e2b1bcc0bf4af7a62356cf98aec4f6