Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Siamak A. Adibi"'
Autor:
Yolanda B. Lombardo, Cynthia Serdikoff, Siamak A. Adibi, Manikkavasagar Thamotharan, Harbhajan S. Paul
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 277:E685-E692
Rat cardiac and skeletal muscles, which have been used as model tissues for studies of regulation of branched-chain α-keto acid (BCKA) oxidation, vary greatly in the activity state of their BCKA dehydrogenase. In the present experiment, we have inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69dd736d409ab9512f5523451e58eaf1
https://doi.org/10.1152/ajpendo.1999.277.4.e685
https://doi.org/10.1152/ajpendo.1999.277.4.e685
Publikováno v:
Journal of Biological Chemistry. 272:11786-11790
Accumulation of products of proteolysis (e.g. dipeptides) in lysosomes may have pathological consequences. In the present experiment we have investigated the existence of a dipeptide transporter in a membrane preparation of liver lysosomes using Gly-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6dde1546c01e0bbe2148ea03899c36
https://doi.org/10.1074/jbc.272.18.11786
https://doi.org/10.1074/jbc.272.18.11786
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 271:E535-E540
Glycylglutamine (Gly-Gln) is stable source of glutamine for parenteral nutrition. In the present study we have investigated whether this dipeptide is transferred intact across the human placenta. Although after 90 min of placental perfusion there was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15665f28e4b4b516ecb411af8a177ccf
https://doi.org/10.1152/ajpendo.1996.271.3.e535
https://doi.org/10.1152/ajpendo.1996.271.3.e535
Autor:
Siamak A. Adibi, Hannelore Daniel
Publikováno v:
The FASEB Journal. 9:1112-1117
Based on the involvement of zinc in hydrolysis of peptides, we hypothesized that Zn2+ may also play a role in peptide transport. To investigate this hypothesis, kidney brush border membrane vesicles (BBMV) were incubated for 30 min with different con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a64311ad57a611fe38cc08d5912bb53
https://doi.org/10.1096/fasebj.9.11.7649411
https://doi.org/10.1096/fasebj.9.11.7649411
Functional separation of dipeptide transport and hydrolysis in kidney brush border membrane vesicles
Autor:
Siamak A. Adibi, Hannelore Daniel
Publikováno v:
The FASEB Journal. 8:753-759
Dipeptides serve as substrates for both transport and hydrolytic processes. This has caused uncertainty as to whether different systems mediate both processes, and if so, whether they can be functionally separated. To investigate these problems, we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::435c525c56990c21bd867b0223ef0e19
https://doi.org/10.1096/fasebj.8.10.8050675
https://doi.org/10.1096/fasebj.8.10.8050675
Publikováno v:
Journal of Biological Chemistry. 269:19427-19434
The present study demonstrates that dexamethasone and 8-(4-chlorophenylthio)adenosine 3',5'-monophosphate (CPT-cAMP), a cAMP analog, increase the substrate flux through branched-chain keto acid dehydrogenase (BCKDH) in primary rat hepatocytes culture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1b0fde116013700e3fc5a29776a511a
https://doi.org/10.1016/s0021-9258(17)32186-5
https://doi.org/10.1016/s0021-9258(17)32186-5
Publikováno v:
Nutrition in Clinical Practice. 8:95-105
The use of intravenous dipeptides shows great promise as an avenue for the provision of amino acids that may otherwise be difficult to deliver via nutrient infusions. The physical/chemical properties and metabolism of numerous dipeptides have now bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21bb6ab74fe3a63513b939b05b351b6c
https://doi.org/10.1177/011542659300800395
https://doi.org/10.1177/011542659300800395
Publikováno v:
The Journal of Nutrition. 123:325-331
A possible source of glutamine, for inclusion in the parenteral solutions, is glycylglutamine. The aim of this article is to review briefly the information on metabolism of glycylglutamine when administered intravenously. The fact that there is effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81c44fe02ada2900a70133f3c2602c60
https://doi.org/10.1093/jn/123.suppl_2.325
https://doi.org/10.1093/jn/123.suppl_2.325
Publikováno v:
Gastroenterology. 103:3-11
Using in vivo and in vitro techniques, the mechanism by which intestinal mucosa obtains glutamine from luminal oligopeptides was investigated in humans. The rate of hydrolysis by mucosal brush border membrane was more than threefold greater for alany
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab4f109984b6ae448f9893d4b4cf1cf4
https://doi.org/10.1016/0016-5085(92)91088-l
https://doi.org/10.1016/0016-5085(92)91088-l
Autor:
Siamak A. Adibi, H S Paul
Publikováno v:
Journal of Biological Chemistry. 267:11208-11214
We and others have previously shown that octanoate increases the oxidation of branched chain amino acids (BCAA) in skeletal muscle. The present study was designed to investigate the mechanism of this increased oxidation. Studies were performed with r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cebffcff2e257c70f99ec643f2d72747
https://doi.org/10.1016/s0021-9258(19)49897-9
https://doi.org/10.1016/s0021-9258(19)49897-9