Diagnostic value of tumor markers in identifying favorable or unfavorable subsets in patients with cancer of unknown primary: a retrospective study

Autor: Shigemasa Takamizawa, Tatsunori Shimoi, Masayuki Yoshida, Momoko Tokura, Shu Yazaki, Chiharu Mizoguchi, Ayumi Saito, Shosuke Kita, Kasumi Yamamoto, Yuki Kojima, Hitomi Sumiyoshi-Okuma, Tadaaki Nishikawa, Emi Noguchi, Kazuki Sudo, Kan Yonemori

Publikováno v: BMC Cancer, Vol 22, Iss 1, Pp 1-8 (2022)

Abstract Background Routine measurement of tumor markers is not recommended in daily clinical practice for patients with cancer of unknown primary (CUP). We evaluated the diagnostic value of tumor markers in identifying favorable or unfavorable subse

Externí odkaz: https://doaj.org/article/d23e0071b7ef404aa69907d7bc7e6912

Glicovacina CD44 para cancro da bexiga: síntese, validação pré-clínica e soluções biotecnológicas associadas

Autor: Ferreira, Eduardo da Silva

Bladder cancer (BC) is the most common malignancy of the urinary tract, with high recurrence rates. Aberrant glycosylation of the proteins and lipids of the bladder cancer cells leads to the generation of truncated O-glycans, which have been linked t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2292::670a1f04b93b5969bfcd8e6d1cc8499c
http://hdl.handle.net/10773/37150

Development of a novel target module redirecting UniCAR T cells to Sialyl Tn-expressing tumor cells

Autor: Loureiro, L., Feldmann, A., Bergmann, R., Koristka, S., Berndt, N., Arndt, C., Pietzsch, J., Novo, C., Videira, P., Bachmann, M.

Publikováno v: Blood Cancer Journal, Vol 8, Iss 9, Pp 1-6 (2018)
Blood Cancer Journal 8(2018), 81

The development of antibody-based therapies has been driven by progress in the immune response field culminating in the development of chimeric antigen receptors (CARs) as a promising approach in cancer immunotherapy. Nevertheless, drawbacks associat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f9b7b99a5904b4ecd5cf92f7f3b9d2b4
http://link.springer.com/article/10.1038/s41408-018-0113-4

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The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer

Autor: Munkley, Jennifer, Oltean, Sebastian, Vodák, Daniel, Wilson, Brian T., Livermore, Karen E., Zhou, Yan, Star, Eleanor, Floros, Vasileios I., Johannessen, Bjarne, Knight, Bridget, McCullagh, Paul, McGrath, John, Crundwell, Malcolm, Skotheim, Rolf I., Robson, Craig N., Leung, Hing Y., Harries, Lorna W., Rajan, Prabhakar, Mills, Ian G., Elliott, David J.

Publikováno v: Munkley, J, Oltean, S, Vodák, D, Wilson, B T, Livermore, K E, Zhou, Y, Star, E, Floros, V I, Johannessen, B, Knight, B, McCullagh, P, McGrath, J, Crundwell, M, Skotheim, R I, Robson, C N, Leung, H Y, Harries, L W, Rajan, P, Mills, I G & Elliott, D J 2015, ' The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer ', Oncotarget, vol. 6, no. 33, pp. 34358-74 . https://doi.org/10.18632/oncotarget.6024
Munkley, J, Oltean, S, Vodák, D, Wilson, B T, Livermore, K E, Zhou, Y, Star, E, Floros, V I, Johannessen, B, Knight, B, McCullagh, P, McGrath, J, Crundwell, M, Skotheim, R I, Robson, C N, Leung, H Y, Harries, L W, Rajan, P, Mills, I G & Elliott, D J 2015, ' The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer ', Oncotarget, vol. 6, no. 33, pp. 34358-34374 . https://doi.org/10.18632/oncotarget.6024
Oncotarget

Patterns of glycosylation are important in cancer, but the molecular mechanisms that drive changes are often poorly understood. The androgen receptor drives prostate cancer (PCa) development and progression to lethal metastatic castration-resistant d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::60cb37a782dd2ccef5b9f94171fc687b
https://research-information.bris.ac.uk/ws/files/73875788/6024_83505_4_PB.pdf