Sialic Acid-Siglec-E Interactions Regulate the Response of Neonatal Macrophages to Group B Streptococcus.

Autor: Lund SJ; Department of Pediatrics, University of California, San Diego, La Jolla, CA., Del Rosario PGB; Department of Pediatrics, University of California, San Diego, La Jolla, CA.; Rady Children's Hospital, San Diego, CA., Honda A; Department of Pediatrics, University of California, San Diego, La Jolla, CA., Caoili KJ; Department of Pediatrics, Stanford University, Palo Alto, CA., Hoeksema MA; Department of Medical Biochemistry, Amsterdam University Medical Center, Amsterdam Zuidoost, the Netherlands., Nizet V; Department of Pediatrics, University of California, San Diego, La Jolla, CA., Patras KA; Department of Molecular Virology and Microbiology, Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, TX., Prince LS; Department of Pediatrics, Stanford University, Palo Alto, CA.

Publikováno v: ImmunoHorizons [Immunohorizons] 2024 May 01; Vol. 8 (5), pp. 384-396.

Basic Science and Pathogenesis.

Autor: Morello BS; Bioneer, Horsholm, Denmark., Shatri EB; Bioneer, Horsholm, Denmark., Frandsen S; Bioneer, Horsholm, Denmark., Schmid B; Bioneer, Horsholm, Denmark., Thirstrup K; Bioneer, Horsholm, Denmark., Holst B; Bioneer, Horsholm, Denmark.

Publikováno v: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2024 Dec; Vol. 20 Suppl 1, pp. e088752.

Generation and characterization of two iPSC lines derived from subjects with Free Sialic Acid Storage Disorder (FSASD).

Autor: Sabir MS; NIH Undiagnosed Diseases Program, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA; NIH Oxford-Cambridge Scholars Program, University of Oxford, Oxford, UK., Leoyklang P; Human Biochemical Genetics Section, Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Hackbarth ME; Human Biochemical Genetics Section, Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Pak E; Cytogenetics and Microscopy Core, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Dutra A; Cytogenetics and Microscopy Core, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Tait R; ALSTEM, Inc., Richmond, CA, USA., Pollard L; Biochemical Diagnostic Laboratory, Greenwood Genetic Center, Greenwood, SC, USA., Adams DR; NIH Undiagnosed Diseases Program, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA; Office of the Clinical Director, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Gahl WA; NIH Undiagnosed Diseases Program, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA; Human Biochemical Genetics Section, Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Huizing M; Human Biochemical Genetics Section, Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Malicdan MCV; NIH Undiagnosed Diseases Program, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA; Human Biochemical Genetics Section, Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: maychristine.malicdan@nih.gov.

Publikováno v: Stem cell research [Stem Cell Res] 2024 Dec; Vol. 81, pp. 103600. Date of Electronic Publication: 2024 Oct 22.

CD22 blockade exacerbates neuroinflammation in Neuromyelitis optica spectrum disorder.

Autor: Zhang W; Tianjin Neurological Institute, Department of Neurology, Tianjin Institute of Immunology, State Key Laboratory of Experimental Hematology, International Joint Laboratory of Ocular Diseases, Haihe Laboratory of Cell Ecosystem, Laboratory of Post-Neuroinjury Neurorepair and Regeneration in Central Nervous System Tianjin & Ministry of Education, Ministry of Education, Tianjin Medical University General Hospital, Tianjin, 300052, China., Han Y; Tianjin Neurological Institute, Department of Neurology, Tianjin Institute of Immunology, State Key Laboratory of Experimental Hematology, International Joint Laboratory of Ocular Diseases, Haihe Laboratory of Cell Ecosystem, Laboratory of Post-Neuroinjury Neurorepair and Regeneration in Central Nervous System Tianjin & Ministry of Education, Ministry of Education, Tianjin Medical University General Hospital, Tianjin, 300052, China., Huang H; Tianjin Neurological Institute, Department of Neurology, Tianjin Institute of Immunology, State Key Laboratory of Experimental Hematology, International Joint Laboratory of Ocular Diseases, Haihe Laboratory of Cell Ecosystem, Laboratory of Post-Neuroinjury Neurorepair and Regeneration in Central Nervous System Tianjin & Ministry of Education, Ministry of Education, Tianjin Medical University General Hospital, Tianjin, 300052, China., Su Y; Department of Neurology, Tangdu Hospital, Air Force Medical University, Xi'an, Shaanxi, 710038, China., Ren H; Tianjin Neurological Institute, Department of Neurology, Tianjin Institute of Immunology, State Key Laboratory of Experimental Hematology, International Joint Laboratory of Ocular Diseases, Haihe Laboratory of Cell Ecosystem, Laboratory of Post-Neuroinjury Neurorepair and Regeneration in Central Nervous System Tianjin & Ministry of Education, Ministry of Education, Tianjin Medical University General Hospital, Tianjin, 300052, China., Qi C; Tianjin Neurological Institute, Department of Neurology, Tianjin Institute of Immunology, State Key Laboratory of Experimental Hematology, International Joint Laboratory of Ocular Diseases, Haihe Laboratory of Cell Ecosystem, Laboratory of Post-Neuroinjury Neurorepair and Regeneration in Central Nervous System Tianjin & Ministry of Education, Ministry of Education, Tianjin Medical University General Hospital, Tianjin, 300052, China., Li J; Tianjin Neurological Institute, Department of Neurology, Tianjin Institute of Immunology, State Key Laboratory of Experimental Hematology, International Joint Laboratory of Ocular Diseases, Haihe Laboratory of Cell Ecosystem, Laboratory of Post-Neuroinjury Neurorepair and Regeneration in Central Nervous System Tianjin & Ministry of Education, Ministry of Education, Tianjin Medical University General Hospital, Tianjin, 300052, China., Yang H; Tianjin Neurological Institute, Department of Neurology, Tianjin Institute of Immunology, State Key Laboratory of Experimental Hematology, International Joint Laboratory of Ocular Diseases, Haihe Laboratory of Cell Ecosystem, Laboratory of Post-Neuroinjury Neurorepair and Regeneration in Central Nervous System Tianjin & Ministry of Education, Ministry of Education, Tianjin Medical University General Hospital, Tianjin, 300052, China., Xu J; Tianjin Neurological Institute, Department of Neurology, Tianjin Institute of Immunology, State Key Laboratory of Experimental Hematology, International Joint Laboratory of Ocular Diseases, Haihe Laboratory of Cell Ecosystem, Laboratory of Post-Neuroinjury Neurorepair and Regeneration in Central Nervous System Tianjin & Ministry of Education, Ministry of Education, Tianjin Medical University General Hospital, Tianjin, 300052, China., Chang G; Tianjin Neurological Institute, Department of Neurology, Tianjin Institute of Immunology, State Key Laboratory of Experimental Hematology, International Joint Laboratory of Ocular Diseases, Haihe Laboratory of Cell Ecosystem, Laboratory of Post-Neuroinjury Neurorepair and Regeneration in Central Nervous System Tianjin & Ministry of Education, Ministry of Education, Tianjin Medical University General Hospital, Tianjin, 300052, China., Qiu W; Department of Neurosurgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, 550001, China., Liu Q; Tianjin Neurological Institute, Department of Neurology, Tianjin Institute of Immunology, State Key Laboratory of Experimental Hematology, International Joint Laboratory of Ocular Diseases, Haihe Laboratory of Cell Ecosystem, Laboratory of Post-Neuroinjury Neurorepair and Regeneration in Central Nervous System Tianjin & Ministry of Education, Ministry of Education, Tianjin Medical University General Hospital, Tianjin, 300052, China. qliu@tmu.edu.cn., Chang T; Department of Neurology, Tangdu Hospital, Air Force Medical University, Xi'an, Shaanxi, 710038, China. changting1981@163.com.

Publikováno v: Journal of neuroinflammation [J Neuroinflammation] 2024 Nov 30; Vol. 21 (1), pp. 313. Date of Electronic Publication: 2024 Nov 30.

A bispecific antibody targeting the Ig domains of Siglec-E displays enhanced antitumor effects.

Autor: Zhao D; Department of Obstetrics and Gynecology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, University of Science and Technology of China, Hefei, Anhui 230001, China., Liu M; Laboratory of Structural Immunology, Key Laboratory of Immune Response and Immunotherapy, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230027, China., Zeng W; Laboratory of Structural Immunology, Key Laboratory of Immune Response and Immunotherapy, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230027, China., Chen S; Laboratory of Structural Immunology, Key Laboratory of Immune Response and Immunotherapy, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230027, China., Bibi S; Laboratory of Structural Immunology, Key Laboratory of Immune Response and Immunotherapy, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230027, China., Wang M; Laboratory of Structural Immunology, Key Laboratory of Immune Response and Immunotherapy, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230027, China., Huang X; Laboratory of Structural Immunology, Key Laboratory of Immune Response and Immunotherapy, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230027, China., Zhu F; Laboratory of Structural Immunology, Key Laboratory of Immune Response and Immunotherapy, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230027, China., Zheng P; Laboratory of Structural Immunology, Key Laboratory of Immune Response and Immunotherapy, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230027, China., Gao Y; Laboratory of Structural Immunology, Key Laboratory of Immune Response and Immunotherapy, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230027, China., Wu Q; Laboratory of Structural Immunology, Key Laboratory of Immune Response and Immunotherapy, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230027, China., Zhang H; College of Medicine, Lishui University, Lishui, 323000, China., Cheng Q; Institute of Health and Medicine, Hefei Comprehensive National Science Center, Hefei, Anhui, China., Sun C; Laboratory of Structural Immunology, Key Laboratory of Immune Response and Immunotherapy, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230027, China., Bai L; Laboratory of Structural Immunology, Key Laboratory of Immune Response and Immunotherapy, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230027, China., Zhu Z; Laboratory of Structural Immunology, Key Laboratory of Immune Response and Immunotherapy, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230027, China; Anhui Genebiol Biotech. LTD., Hefei, 230000, China., Li B; Laboratory of Structural Immunology, Key Laboratory of Immune Response and Immunotherapy, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230027, China; Anhui Genebiol Biotech. LTD., Hefei, 230000, China., Wu S; College of Medicine, Lishui University, Lishui, 323000, China., Shang Y; Anhui Genebiol Biotech. LTD., Hefei, 230000, China., Hasi C; Sonid Suoqi Animal Husbandry Workstation, Xilinhot City, Inner Mongolia Xilin Gol League, China., Ma H; Laboratory of Structural Immunology, Key Laboratory of Immune Response and Immunotherapy, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230027, China., Zhou S; Department of Breast Oncology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China. Hefei, Anhui, 230031, China; Department of Breast Oncology, Anhui Provincial Cancer Hospital. Hefei, Anhui, 230031, China. Electronic address: zhoushoubingseu@126.com., Jin T; Department of Obstetrics and Gynecology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, University of Science and Technology of China, Hefei, Anhui 230001, China; Laboratory of Structural Immunology, Key Laboratory of Immune Response and Immunotherapy, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230027, China; College of Medicine, Lishui University, Lishui, 323000, China; Institute of Health and Medicine, Hefei Comprehensive National Science Center, Hefei, Anhui, China; Anhui Genebiol Biotech. LTD., Hefei, 230000, China; Biomedical Sciences and Health Laboratory of Anhui Province, University of Science & Technology of China, Hefei 230027, China; Clinical Research Hospital of Chinese Academy of Sciences (Hefei), University of Science and Technology of China, Hefei 230001, China. Electronic address: jint@ustc.edu.cn.

Publikováno v: International journal of biological macromolecules [Int J Biol Macromol] 2024 Nov; Vol. 281 (Pt 4), pp. 136635. Date of Electronic Publication: 2024 Oct 16.