Eliciting the mitochondrial unfolded protein response via NAD(+) repletion reverses fatty liver disease

Autor: Gariani K, Menzies KJ, Ryu D, Wegner CJ, Wang X, Ropelle ER, Moullan N, Zhang H, Perino A, Lemos V, Kim B, Park YK, Piersigilli A, Pham TX, Yang Y, Siah Ku C, Koo Sl, Fomitchova A, Canto C, Schoonjans K, Sauve AA, Lee JY, Auwerx J

Publikováno v: Gariani, Karim; Menzies, Keir J; Ryu, Dongryeol; Wegner, Casey J; Wang, Xu; Ropelle, Eduardo R; Moullan, Norman; Zhang, Hongbo; Perino, Alessia; Lemos, Vera; Kim, Bohkyung; Park, Young-Ki; Piersigilli, Alessandra; Pham, Tho X; Yang, Yue; Siah Ku, Chai; Koo, Sung I; Fomitchova, Anna; Cantó, Carlos; Schoonjans, Kristina; ... (2015). Eliciting the mitochondrial unfolded protein response via NAD(+) repletion reverses fatty liver disease. Hepatology, 63(4), pp. 1190-1204. Wiley Interscience 10.1002/hep.28245
Hepatology

With no approved pharmacological treatment non alcoholic fatty liver disease (NAFLD) is now the most common cause of chronic liver disease in western countries and its worldwide prevalence continues to increase along with the growing obesity epidemic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6a04bbcd06cb803c814e02252676f710
https://boris.unibe.ch/75642/1/hep28245.pdf