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Plasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation
Autor: Mikus MS, Kolmert J, Andersson LI, Östling J, Knowles RG, Gómez C, Ericsson M, Thörngren JO, Khoonsari PE, Dahlén B, Kupczyk M, De Meulder B, Auffray C, Bakke PS, Beghe B, Bel EH, Caruso M, Chanez P, Chawes B, Fowler SJ, Gaga M, Geiser T, Gjomarkaj M, Horváth I, Howarth PH, Johnston SL, Joos G, Krug N, Montuschi P, Musial J, Ni?ankowska-Mogilnicka E, Olsson HK, Papi A, Rabe KF, Sandström T, Shaw DE, Siafakas NM, Uhlen M, Riley JH, Bates S, Middelveld RJM, Wheelock CE, Chung KF, Adcock IM, Sterk PJ, Djukanovic R, Nilsson P, Dahlén SE, James A, U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease outcome) Study Group, BIOAIR (Longitudinal Assessment of Clinical Course, Biomarkers in Severe Chronic Airway Disease) Consortium.
Publikováno v: The European respiratory journal 59 (2022).
info:cnr-pdr/source/autori:Mikus MS; Kolmert J; Andersson LI; Östling J; Knowles RG; Gómez C; Ericsson M; Thörngren JO; Khoonsari PE; Dahlén B; Kupczyk M; De Meulder B; Auffray C; Bakke PS; Beghe B; Bel EH; Caruso M; Chanez P; Chawes B; Fowler SJ; Gaga M; Geiser T; Gjomarkaj M; Horváth I; Howarth PH; Johnston SL; Joos G; Krug N; Montuschi P; Musial J; Ni?ankowska-Mogilnicka E; Olsson HK; Papi A; Rabe KF; Sandström T; Shaw DE; Siafakas NM; Uhlen M; Riley JH; Bates S; Middelveld RJM; Wheelock CE; Chung KF; Adcock IM; Sterk PJ; Djukanovic R; Nilsson P; Dahlén SE; James A; U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease outcome) Study Group; BIOAIR (Longitudinal Assessment of Clinical Course and Biomarkers in Severe Chronic Airway Disease) Consortium./titolo:Plasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation/doi:/rivista:The European respiratory journal/anno:2022/pagina_da:/pagina_a:/intervallo_pagine:/volume:59
Rationale: Asthma phenotyping requires novel biomarker discovery. Objectives: To identify plasma biomarkers associated with asthma phenotypes by application of a new proteomic panel to samples from two well-characterized cohorts of severe (SA) and mi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::b6811d35e98b549737ac2b607ef7c028
https://publications.cnr.it/doc/459421
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3
Akademický článek
Plasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation.
Autor: Sparreman Mikus M; Dept of Protein Science, KTH Royal Institute of Technology, SciLifeLab, Stockholm, Sweden maria.mikus@ki.se.; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Kolmert J; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden., Andersson LI; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden., Östling J; PEXA AB, Gothenburg, Sweden., Knowles RG; Knowles Consulting, Stevenage Bioscience Catalyst, Stevenage, UK., Gómez C; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden., Ericsson M; Dept of Laboratory Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden., Thörngren JO; Dept of Laboratory Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden., Emami Khoonsari P; Dept of Biochemistry and Biophysics, National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Solna, Sweden., Dahlén B; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden.; Dept of Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden., Kupczyk M; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden.; Dept of Internal Medicine, Asthma and Allergy, Medical University of Lodz, University of Lodz, Lodz, Poland., De Meulder B; European Institute for Systems Biology and Medicine, Lyon, France., Auffray C; European Institute for Systems Biology and Medicine, Lyon, France., Bakke PS; Dept of Clinical Science, University of Bergen, Bergen, Norway., Beghe B; Dept of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy., Bel EH; Dept of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Caruso M; Dept of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy., Chanez P; Assistance Publique des Hôpitaux de Marseille, Clinique des Bronches, Allergies et Sommeil, Aix Marseille Université, Marseille, France., Chawes B; COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark., Fowler SJ; Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester; Manchester Academic Health Science Centre and NIHR Manchester Biomedical Research Centre, Manchester University Hospitals NHS Foundation Trust, Manchester, UK., Gaga M; Respiratory Medicine Dept and Asthma Centre, Athens Chest Hospital 'Sotiria', University of Athens, Athens, Greece., Geiser T; Dept for Pulmonary Medicine, University Hospital and University of Bern, Bern, Switzerland., Gjomarkaj M; Institute for Research and Biomedical Innovation, Italian National Research Council, Palermo, Italy., Horváth I; Dept of Pulmonology, Semmelweis University, Budapest, Hungary., Howarth PH; NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, and Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Johnston SL; National Heart and Lung Institute, Imperial College London, London, UK., Joos G; Dept of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.; Dept of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium., Krug N; Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany., Montuschi P; Dept of Pharmacology, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Musial J; Dept of Internal Medicine, Jagiellonian University Medical College, Krakow, Poland., Niżankowska-Mogilnicka E; Dept of Internal Medicine, Jagiellonian University Medical College, Krakow, Poland., Olsson HK; Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Papi A; Division of lnternal and Cardiorespiratory Medicine, University of Ferrara, Ferrara, Italy., Rabe KF; Dept of Internal Medicine, Christian Albrechts University Kiel, Kiel, Germany., Sandström T; Dept of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Shaw DE; Respiratory Research Unit, University of Nottingham, Nottingham, UK., Siafakas NM; Dept of Thoracic Medicine, Medical School, University of Crete, Heraklion, Crete, Greece., Uhlén M; Dept of Protein Science, KTH Royal Institute of Technology, SciLifeLab, Stockholm, Sweden.; Dept of Neuroscience, Karolinska Institutet, Stockholm, Sweden., Riley JH; Respiratory Therapeutic Unit, GlaxoSmithKline, London, UK., Bates S; Respiratory Therapeutic Unit, GlaxoSmithKline, London, UK., Middelveld RJM; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden., Wheelock CE; Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden.; Dept of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.; Dept of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden., Chung KF; National Heart and Lung Institute, Imperial College London, London, UK., Adcock IM; National Heart and Lung Institute, Imperial College London, London, UK., Sterk PJ; Dept of Respiratory Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Djukanovic R; NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, and Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Nilsson P; Dept of Protein Science, KTH Royal Institute of Technology, SciLifeLab, Stockholm, Sweden., Dahlén SE; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden.; Dept of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden., James A; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden.
Publikováno v: The European respiratory journal [Eur Respir J] 2022 Feb 17; Vol. 59 (2). Date of Electronic Publication: 2022 Feb 17 (Print Publication: 2022).
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4
Akademický článek
Lung function fluctuation patterns unveil asthma and COPD phenotypes unrelated to type 2 inflammation.
Autor: Delgado-Eckert E; University of Basel, University Children's Hospital, Basel, Switzerland., James A; Center for Allergy Research, Karolinska Institutet, Stockholm, Sweden., Meier-Girard D; University of Basel, University Children's Hospital, Basel, Switzerland., Kupczyk M; Center for Allergy Research, Karolinska Institutet, Stockholm, Sweden; Department of Internal Medicine, Asthma and Allergy, Medical University of Lodz, Lodz, Poland., Andersson LI; Center for Allergy Research, Karolinska Institutet, Stockholm, Sweden., Bossios A; Center for Allergy Research, Karolinska Institutet, Stockholm, Sweden; Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Huddinge and Department of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden., Mikus M; Center for Allergy Research, Karolinska Institutet, Stockholm, Sweden., Ono J; Shino-Test Corporation Ltd, Sagamihara, Japan., Izuhara K; Division of Medical Biochemistry, Department of Biomolecular Sciences, Saga Medical School, Saga, Japan., Middelveld R; Center for Allergy Research, Karolinska Institutet, Stockholm, Sweden., Dahlén B; Center for Allergy Research, Karolinska Institutet, Stockholm, Sweden; Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Huddinge and Department of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden., Gaga M; University of Athens, Athens, Greece., Siafakas NM; University of Crete, Crete, Greece., Papi A; University of Ferrara, Ferrara, Italy., Beghe B; University of Modena and Reggio Emilia, Italy., Joos G; University of Ghent, Ghent, Belgium., Rabe KF; Christian Albrechts University Kiel, Kiel, Germany., Sterk PJ; Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Bel EH; Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Johnston SL; The Imperial College of Science and Technology, London, United Kingdom., Chanez P; University of Marseilles, Marseilles, France., Gjomarkaj M; Italian Research Council, Palermo, Italy., Howarth PH; University of Southampton, Southampton, United Kingdom., Niżankowska-Mogilnicka E; The Jagellonian University, Krakow, Poland., Dahlén SE; Center for Allergy Research, Karolinska Institutet, Stockholm, Sweden. Electronic address: Sven-Erik.Dahlen@ki.se., Frey U; University of Basel, University Children's Hospital, Basel, Switzerland.
Publikováno v: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2021 Aug; Vol. 148 (2), pp. 407-419. Date of Electronic Publication: 2021 Feb 03.
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5
Akademický článek
Risks of Artificial Intelligence (AI) in Medicine.
Autor: Siafakas, Nikolaos1 siafakan@uoc.gr, Vasarmidi, Eirini2
Publikováno v: Underground Space (2096-2754). Dec2024, Vol. 19, p1-5. 5p.
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6
Akademický článek
Mitochondrial dysfunction and impaired DNA damage repair through PICT1 dysregulation in alveolar type II cells in emphysema.
Autor: Simborio, Hannah1 (AUTHOR), Hayek, Hassan1,2 (AUTHOR), Kosmider, Beata1,2 (AUTHOR), Elrod, John W.3 (AUTHOR), Bolla, Sudhir4 (AUTHOR), Marchetti, Nathaniel4 (AUTHOR), Criner, Gerard J.4 (AUTHOR), Bahmed, Karim1,2 (AUTHOR) karim.bahmed@temple.edu
Publikováno v: Cell Communication & Signaling. 11/22/2024, Vol. 22 Issue 1, p1-14. 14p.
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8
Akademický článek
Improving the Transparency and Replicability of Consensus Methods: Respiratory Medicine as a Case Example.
Autor: Rolfe, Mark J (AUTHOR), Winchester, Christopher C (AUTHOR), Chisholm, Alison (AUTHOR), Price, David B (AUTHOR)
Publikováno v: Pragmatic & Observational Research. Oct2024, Vol. 15, p201-207. 7p.
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10
Akademický článek
Machine learning for accurate detection of small airway dysfunction-related respiratory changes: an observational study.
Autor: Xu, Wen-Jing1 (AUTHOR), Shang, Wen-Yi2 (AUTHOR), Feng, Jia-Ming3 (AUTHOR), Song, Xin-Yue1 (AUTHOR), Li, Liang-Yuan1 (AUTHOR), Xie, Xin-Peng4 (AUTHOR), Wang, Yan-Mei5 (AUTHOR), Liang, Bin-Miao1 (AUTHOR) liangbinmiao@163.com
Publikováno v: Respiratory Research. 7/24/2024, Vol. 25 Issue 1, p1-11. 11p.
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