Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Siadak, Anthony W."'
Autor:
Sakata, Naoki, Hamelmann, Eckard, Siadak, Anthony W., Terada, Naohiro, Gerwins, Pär, Aruffo, Alejandro, Johnson, Gary L., Gelfand, Erwin W.
Publikováno v:
In Cellular Immunology 1 May 2000 201(2):109-123
Autor:
Daniel C. Anderson, Shannon R. Cowan, Randall Hennigar, Kris Odom, Angello Lin, Joel Trambley, Alejandro Aruffo, Diane Hollenbaugh, Christian P. Larsen, Siadak Anthony W, Elizabeth Strobert, Thomas C. Pearson, Robert A. Bray
Publikováno v:
Transplantation. 74:933-940
Background. Organ transplant recipients currently require lifetime immunosuppressive therapy, with its accompanying side effects. Biological agents that block T-cell costimulatory pathways are important components of strategies being developed to ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc85cb3bfef070412d97b29b29909226
https://doi.org/10.1097/00007890-200210150-00006
https://doi.org/10.1097/00007890-200210150-00006
Autor:
Dawn Palmer, Alejandro Aruffo, Maurizia D'Egidio, Gena S. Whitney, Gary C. Starling, Siadak Anthony W, Michael A. Bowen, Jürgen Bajorath, Jörg Kobarg
Publikováno v:
European Journal of Immunology. 27:1469-1478
Activated leukocyte cell adhesion molecule (ALCAM; CD166) is a member of the immunoglobulin gene superfamily (IgSF) which is expressed by activated leukocytes and thymic epithelial cells and is a ligand for the lymphocyte antigen CD6. Herein, we repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2df0e519a3260ca3744f3722e864df6d
https://doi.org/10.1002/eji.1830270625
https://doi.org/10.1002/eji.1830270625
Autor:
Jürgen Bajorath, Siadak Anthony W, Michael G. Neubauer, Dale L. Bodian, A Aruffo, John E. Skonier, Michael A. Bowen
Publikováno v:
Biochemistry. 36:2637-2641
CD6 is a member of the scavenger receptor cysteine rich protein superfamily (SRCRSF). This family includes many cell surface proteins whose three-dimensional structures and functions are presently not well understood. The extracellular region of CD6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2be6adaac6a668d7a681ad1bdb3a1ad
https://doi.org/10.1021/bi962560+
https://doi.org/10.1021/bi962560+
Autor:
John Emswiler, Siadak Anthony W, Jan N. Chalupny, Robert S. Mittler, Kerry Klussman, Hong Raecho, Christian P. Larsen, Walter W. Shuford, Deryk T. Loo, Douglas D. Tritchler, Jeffrey A. Ledbetter, T. Joseph Brown, Thomas C. Pearson, Alejandro Aruffo
Publikováno v:
The Journal of Experimental Medicine
The 4-1BB receptor is an inducible type I membrane protein and member of the tumor necrosis factor receptor (TNFR) superfamily that is rapidly expressed on the surface of CD4+ and CD8+ T cells after antigen- or mitogen-induced activation. Cross-linki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c53374a22a4c185f75007c6fb8cfc2
http://europepmc.org/articles/PMC2198949
http://europepmc.org/articles/PMC2198949
Autor:
Siadak Anthony W, A Aruffo, Randolph J. Noelle, Diane Hollenbaugh, Gordon Marcia L, Jürgen Bajorath, N J Chalupny, T L Spoon, John Marken
Publikováno v:
Biochemistry. 34:9884-9892
The interaction between gp39 (CD40L, TRAP, T-BAM) on activated T cells and mast cells and CD40 on antigen-presenting cells modulates immune responses. Gp39 and CD40 are homologous to tumor necrosis factor (TNF) and its receptor (TNFR), respectively.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9e1054d31254eb5c8c5f1c73f7a1b7
https://doi.org/10.1021/bi00031a009
https://doi.org/10.1021/bi00031a009
Autor:
Gordon Marcia L, N. Jan Chalupny, John E. Skonier, Randolph J. Noelle, Hans D. Ochs, Siadak Anthony W, Juergen Bajorath, Alejandro Aruffo, Diane Hollenbaugh, John Marken
Publikováno v:
Biochemistry. 34:1833-1844
Interactions between gp39 (CD40L, TRAP, T-BAM) on activated T cells and CD40 on antigen-presenting cells play an important role in regulating antibody production by B cells, cytokine production by monocytes, and other immune responses which require T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a878884d5e0fd6b1627bbb0143a115c0
https://doi.org/10.1021/bi00006a003
https://doi.org/10.1021/bi00006a003
Autor:
Alejandro Aruffo, Naoki Sakata, Eckhard Hamelmann, Gary L. Johnson, Naohiro Terada, Pär Gerwins, Erwin W. Gelfand, Siadak Anthony W
Publikováno v:
Cellular immunology. 201(2)
Ligation of CD40 using anti-CD40 or soluble CD40-ligand activates numerous intracellular kinases which transduce signals to the nucleus. The nature whereby these signaling events are coupled to distal functional events in B cells is poorly understood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92796783f2dfd9c1fe408099a47ae091
https://pubmed.ncbi.nlm.nih.gov/10831320
https://pubmed.ncbi.nlm.nih.gov/10831320
Autor:
Jürgen Bajorath, Steven G. Nadler, Siadak Anthony W, Alison R. Malacko, Hans Marquardt, Michael A. Bowen, Alejandro Aruffo, Brett Modrell
Publikováno v:
The Journal of biological chemistry. 271(29)
Activated leukocyte cell adhesion molecule (ALCAM) was recently identified as a ligand for CD6, a signaling receptor expressed on T cells, a subset of B cells, and some cells in the brain. Receptor-ligand binding assays, antibody blocking experiments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a85cd1f1edeb0c70c891c6c050144650
https://pubmed.ncbi.nlm.nih.gov/8663238
https://pubmed.ncbi.nlm.nih.gov/8663238
Autor:
Siadak Anthony W, Gena S. Whitney, Michael A. Bowen, Maj-Britt C. Llewellyn, Gary C. Starling, Alejandro Aruffo, Andrew G. Farr
Publikováno v:
European journal of immunology. 26(4)
Human CD6 is a cell surface protein expressed by thymocytes, mature T cells, a subset of B cells and certain cells of the brain. On human T cells, CD6 has been shown to act as a co-stimulatory molecule which modulates T cell receptor (TCR)-mediated T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b8aa65f334aaf51adbddc72b908521
https://pubmed.ncbi.nlm.nih.gov/8625962
https://pubmed.ncbi.nlm.nih.gov/8625962