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Analysis of Composition Differences between Huazhou Citri Grandis Exocarpium and Guangxi Citri Grandis Exocarpium Based on Portable GC-MS and HS/SPME-GC×GC-TOF MS

Autor: Kai-xuan LI, Luo-xu HUANG, Man-man WU, Jing-wei XU, Guo-bin TAN, Si-fan LUO, Zhen ZHOU

Publikováno v: Zhipu Xuebao, Vol 45, Iss 5, Pp 631-639 (2024)

The volatile components of Citri Grandis Exocarpium from Huazhou (CGEH) and Guangxi (CGEG) were analyzed by portable gas chromatography-mass spectrometry (GC-MS) and comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry (G

Externí odkaz: https://doaj.org/article/8f621ac0685849808e68bd1a262ba541

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Rapid identification and isolation of neuraminidase inhibitors from mockstrawberry (Duchesnea indica Andr.) based on ligand fishing combined with HR-ESI-Q-TOF-MS

Autor: Si-Fan Luo, Hai-Yan Tian, Caimin Sheng, Chufang Li, Zhengjin Jiang, Ling Chen, Yumei Zhao, Linbo Guo

Publikováno v: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 10, Pp 1846-1855 (2020)

Neuraminidase inhibitors (NAIs) are the mainstay antiviral drugs against influenza infection. In this study, a ligand fishing protocol was developed to screen NAIs using neuraminidase immobilized magnetic beads (NA-MB). After verifying the feasibilit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac5ef3e0d1a8296ae6da16027bbc03c
http://europepmc.org/articles/PMC7606179

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Magnetic beads-based neuraminidase enzyme microreactor as a drug discovery tool for screening inhibitors from compound libraries and fishing ligands from natural products

Autor: Si-Fan Luo, Tingting Zhang, Qiqin Wang, Ruin Moaddel, Lv-Huan Wang, Yumei Zhao, Zhengjin Jiang

Publikováno v: Journal of Chromatography A. 1568:123-130

Neuraminidase (NA) is a glycoside hydrolase that has been proposed as a potential therapeutic target for influenza. Thus, the identification of compounds that modulate NA activity could be of great therapeutic importance. The aim of this study is to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9394351b97c49d75b5cbad3f66500648
https://doi.org/10.1016/j.chroma.2018.07.031

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Isolation and identification ofl/d-lactate-conjugated bufadienolides from toad eggs revealing lactate racemization in amphibians

Autor: Hai-Yan Tian, Ren-Wang Jiang, Wen-Cai Ye, Xiuyong Huang, Lei Wang, Si-fan Luo, Yong Wang, Shi-Wen Zhou, Qingfei Zheng

Publikováno v: Organic & Biomolecular Chemistry. 15:5609-5615

Three pairs of bufadienolide l/d-lactate epimers (1-6) were isolated from the eggs of the toad Bufo bufo gargarizans. The structures were elucidated by using spectroscopic methods, X-ray diffraction analysis and a modified Mosher's method. Compounds

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda158b3b05ff1fac4c3cde7bd63bb00
https://doi.org/10.1039/c7ob01055a

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