Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Si-Yao Lu"'
Autor:
Qiu-Wen Wang, Junhong Qin, Yan-Fen Chen, Yingfeng Tu, Yun-Yun Xing, Yuchen Wang, Lv-Yu Yang, Si-Yao Lu, Libo Geng, Wei Shi, Yiming Yang, Jun Yao
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112691- (2023)
Summary: Copy-number variations (CNVs) of the human 16p11.2 genetic locus are associated with neurodevelopmental disorders, including autism spectrum disorders (ASDs) and schizophrenia. However, it remains largely unclear how this locus is involved i
Externí odkaz:
https://doaj.org/article/f025de9d8fc04a3fbc2c88bde3d09a69
Autor:
Xiu-ting Liu, Zhen-rui Shi, Si-yao Lu, Dan Hong, Xiao-nan Qiu, Guo-zhen Tan, Hui Xiong, Qing Guo, Liangchun Wang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Microabscess of neutrophils in epidermis is one of the histological hallmarks of psoriasis. The axis of neutrophil–keratinocyte has been thought to play a critical role in the pathogenesis of psoriasis. However, the features and mechanism of intera
Externí odkaz:
https://doaj.org/article/a004d04442d74d2a9a813fccfde1c720
Publikováno v:
PLoS Biology, Vol 19, Iss 7, p e3001323 (2021)
Synaptotagmin-7 (Syt7) plays direct or redundant Ca2+ sensor roles in multiple forms of vesicle exocytosis in synapses. Here, we show that Syt7 is a redundant Ca2+ sensor with Syt1/Doc2 to drive spontaneous glutamate release, which functions uniquely
Externí odkaz:
https://doaj.org/article/471f24d819cb49958ece2c15cf58e983
Autor:
Xiao-nan Qiu, Dan Hong, Zhen-rui Shi, Si-yao Lu, Yu-xian Lai, Yan-ling Ren, Xiu-ting Liu, Chi-peng Guo, Guo-zhen Tan, Liang-chun Wang
Publikováno v:
Immunopharmacology & Immunotoxicology; Dec2023, Vol. 45 Issue 6, p692-700, 9p
Autor:
Chong-Lei Fu, Jun Yao, Yan-Fen Chen, Xuan Huang, Qi Xu, Qiu-Wen Wang, Si-Yao Lu, Anbang Dai, Ying-Han Wang, Hui Wei, Yun Chen, Fred H. Gage, Yao-Nan Liu, Wei Shen
Publikováno v:
Proc Natl Acad Sci U S A
Synaptotagmin-7 (Syt7) probably plays an important role in bipolar-like behavioral abnormalities in mice; however, the underlying mechanisms for this have remained elusive. Unlike antidepressants that cause mood overcorrection in bipolar depression,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd848585ca242a8ea4dd3fd43ba0215
https://doi.org/10.1073/pnas.2016416117
https://doi.org/10.1073/pnas.2016416117
Autor:
Xiu-Ting, Liu, Zhen-Rui, Shi, Si-Yao, Lu, Dan, Hong, Xiao-Nan, Qiu, Guo-Zhen, Tan, Hui, Xiong, Qing, Guo, Liangchun, Wang
Publikováno v:
Frontiers in immunology. 13
Microabscess of neutrophils in epidermis is one of the histological hallmarks of psoriasis. The axis of neutrophil-keratinocyte has been thought to play a critical role in the pathogenesis of psoriasis. However, the features and mechanism of interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::38637afd66c82b8d9fceaf8e3fdeac23
https://pubmed.ncbi.nlm.nih.gov/35401573
https://pubmed.ncbi.nlm.nih.gov/35401573
Autor:
Michela Traglia, Si-Yao Lu, Li Gan, Kenneth Wu, Bingkun Li, Lenka Maliskova, Guo Li Ming, Bruce R. Conklin, Lauren A. Weiss, Fadi Jacob, Xiaoyu Yang, Kirsty Jamieson, Yin Shen, Michael Song, Tse Wai Tam, Chao Wang, Jesse R. Dixon, Jun Yao, Xingjie Ren, Luke M. Judge, Ian R. Jones, Yun Li, Hongjun Song
Publikováno v:
Nature genetics, vol 51, iss 8
Nature genetics
Nature genetics
Mutations in gene regulatory elements have been associated with a wide range of complex neuropsychiatric disorders. However, due to their cell-type specificity and difficulties in characterizing their regulatory targets, the ability to identify causa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a735be77366982b363cc29770adc2b9
https://doi.org/10.1038/s41588-019-0472-1
https://doi.org/10.1038/s41588-019-0472-1
Autor:
Si-Yao Lu, Yun Chen, Shuangli Mi, Jieqing Zhao, Jun Yao, Chong-Lei Fu, Wei Shen, Yan-Fen Chen, Yao-Nan Liu, Lin Zhu, Liang Liang, Wei Shi, Bo Yang, Qiu-Wen Wang
Publikováno v:
Proc Natl Acad Sci U S A
microRNA-218 (miR-218) has been linked to several cognition related neurodegenerative and neuropsychiatric disorders. However, whether miR-218 plays a direct role in cognitive functions remains unknown. Here, using the miR-218 knockout (KO) mouse mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c532cd7eac30d0f26e58122419360507
https://europepmc.org/articles/PMC8040660/
https://europepmc.org/articles/PMC8040660/
Autor:
Yun Chen, Yun Li, Yao-Nan Liu, Yi Zheng, Shuangli Mi, Si-Yao Lu, Bo Yang, Jun Yao, Huihui Qi, Yu-Zhou Xu, Wei Shen, Xia Yu, Jian Zhang, Fred H. Gage
Publikováno v:
Nature Neuroscience. 21:447-454
CRISPR-Cas9 has been demonstrated to delete genes in postmitotic neurons. Compared to the establishment of proliferative cell lines or animal strains, it is more challenging to acquire a highly homogeneous consequence of gene editing in a stable neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7748569f98f5274dce970f0025fc82b6
https://doi.org/10.1038/s41593-018-0077-5
https://doi.org/10.1038/s41593-018-0077-5
Publikováno v:
PLoS Biology, Vol 19, Iss 7, p e3001323 (2021)
PLoS Biology
PLoS Biology
Synaptotagmin-7 (Syt7) plays direct or redundant Ca2+ sensor roles in multiple forms of vesicle exocytosis in synapses. Here, we show that Syt7 is a redundant Ca2+ sensor with Syt1/Doc2 to drive spontaneous glutamate release, which functions uniquely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f264cf29e2253cd605e7fe986eaa825
https://doi.org/10.1371/journal.pbio.3001323
https://doi.org/10.1371/journal.pbio.3001323