Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Si-Tu Xue"'
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 178, Iss , Pp 117260- (2024)
The five-year survival rate for patients with hepatocellular carcinoma (HCC) is only 20 %, highlighting the urgent need to identify new therapeutic targets and develop potential therapeutic options to improve patient prognosis. One promising approach
Externí odkaz:
https://doaj.org/article/381554c557514d59a2f0fd0dfad5488a
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 116018- (2024)
Hepatocellular carcinoma (HCC) is one of the most fatal solid malignancies worldwide. Evidence suggests that thrombin stimulates tumor progression via fibrin formation and platelet activation. Meanwhile, we also found a correlation between thrombin a
Externí odkaz:
https://doaj.org/article/96da8da8d80f46c0906314eb9d909f31
Autor:
Zaixin Zhang, Si-tu Xue, Yan Gao, Yingwei Li, Ziying Zhou, Jing Wang, Zhuorong Li, Zhaojian Liu
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-8 (2022)
Abstract FOXM1 is a potent oncogenic transcription factor essential for cancer initiation, progression, and drug resistance. FOXM1 regulatory network is a major predictor of adverse outcomes in various human cancers. Inhibition of FOXM1 transcription
Externí odkaz:
https://doaj.org/article/669365b9dc2847d791e36c8d8d4095d8
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Ovarian cancer (OC) is a gynecological tumor with possibly the worst prognosis, its 5-year survival rate being only 47.4%. The first line of therapy prescribed is chemotherapy consisting of platinum and paclitaxel. The primary reason for treatment fa
Externí odkaz:
https://doaj.org/article/792c8df86d5645c699087a8a9b115cb2
Autor:
Zhuo-Rong Li, Jian-Dong Jiang, Yu-Huan Li, Tian Zhang, Xing-Yue Ji, Bo Wang, Guang-Hui Zheng, Hui-Qiang Wang, Lin-Lin Ma, Wei-Ying He, Si-Tu Xue
Publikováno v:
Molecules, Vol 18, Iss 4, Pp 3789-3805 (2013)
A series of substituted aryl glycoside analogues of gastrodin have been identified as potential anti-influenza agents. The most potent inhibitor 1a exhibited moderate inhibitory activity against the A/Hanfang/359/95(H3N2) and A/FM/1/47(H1N1) strains
Externí odkaz:
https://doaj.org/article/c0867e9517ee465b835e58ffa5486f3a
Autor:
Xing-yue Ji, Si-tu Xue, Guang-hui Zheng, Yan-xing Han, Zong-ying Liu, Jian-dong Jiang, Zhuo-rong Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 1, Iss 2, Pp 93-99 (2011)
Cajanine, a constituent of Cajanaus cajan L., used in traditional Chinese medicine, is a promising drug candidate because of its broad range of bioactivities. However, the total synthesis of cajanine and its derivatives has never been reported. Herei
Externí odkaz:
https://doaj.org/article/5b16e9040a794db1b26d89d120a89b9d
Autor:
Zi-ying Zhou, Lian-qi Sun, Xiao-yang Han, Yong-jian Wang, Zhuo-song Xie, Si-tu Xue, Zhuo-rong Li
Publikováno v:
Journal of Medicinal Chemistry. 66:1742-1760
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2753edee90ca8e3f8356ba02a3eb64cf
https://doi.org/10.1021/acs.jmedchem.2c01377
https://doi.org/10.1021/acs.jmedchem.2c01377
Publikováno v:
Future Medicinal Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4de3997de6bdacf19a4f10261cb6acc
https://doi.org/10.4155/fmc-2023-0118
https://doi.org/10.4155/fmc-2023-0118
Publikováno v:
Future Medicinal Chemistry. 14:207-219
Aim: Given the importance of FOXM1 in the treatment of ovarian cancer, we aimed to identify an excellent specific inhibitor and examined its underlying therapeutic effect. Materials & methods: The binding statistics for FDI-6 with FOXM1 were calculat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::399eccdacb9e46024c63a0d1e481fff5
https://doi.org/10.4155/fmc-2021-0282
https://doi.org/10.4155/fmc-2021-0282
Publikováno v:
Future medicinal chemistry.
Background: Given the benzimidazole derivatives have anti-ovarian cancer effects, the authors aimed to determine whether benzimidazole-2-substituted pyridine and phenyl propenone derivatives exert anti-ovarian cancer activity. Materials & methods: 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a8e803004b82bfe2ffa2da58355e5b
https://pubmed.ncbi.nlm.nih.gov/36373543
https://pubmed.ncbi.nlm.nih.gov/36373543