Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Si-Tong Feng"'
Autor:
Nai-Hong Chen, Si-Tong Feng, Zhi-Peng Li, Xiao-Le Wang, Yu-He Yuan, Ya-Ting Wang, Yi Zhang, Zhen-Zhen Wang
Publikováno v:
Cellular and Molecular Neurobiology. 42:1321-1339
Parkinson's disease (PD) is a severe neurodegenerative disorder caused by the progressive loss of dopaminergic neurons in the substantia nigra and affects millions of people. Currently, mitochondrial dysfunction is considered as a central role in the
Publikováno v:
Cellular and Molecular Neurobiology. 41:1395-1411
Parkinson's disease (PD), as one of the complex neurodegenerative disorders, affects millions of aged people. Although the precise pathogenesis remains mostly unknown, a significant number of studies have demonstrated that mitochondrial dysfunction a
Publikováno v:
European Journal of Neuroscience. 53:2946-2959
The critical role of mitochondrial dysfunction in the pathological mechanisms of neurodegenerative disorders, particularly Parkinson's disease (PD), is well established. Compelling evidence indicates that Parkinson's proteins (e.g., α-synuclein, Par
Efficacy and safety of istradefylline for Parkinson's disease: A systematic review and meta-analysis
Publikováno v:
Neuroscience letters. 774
As an adenosine receptor A2A antagonist, istradefylline is used as an adjunctive agent of levodopa to improve motor symptoms in advanced Parkinson's disease (PD) patients. In this study, we re-evaluated the effects of istradefylline on treating the m
Publikováno v:
European journal of pharmacology. 927
Depressive symptom is the prevailing non-motor symptom of Parkinson's disease (PD). Drug treatments for depressed PD (dPD) can mitigate the symptoms of patients. However, the results are discordant and need further analysis. This systematic review wi
Autor:
Xiao-Le, Wang, Si-Tong, Feng, Ya-Ting, Wang, Ning-Ning, Zhang, Zhen-Yu, Guo, Xu, Yan, Yu-He, Yuan, Zhen-Zhen, Wang, Nai-Hong, Chen, Yi, Zhang
Publikováno v:
Phytomedicine. 104:154281
Parkinson's disease (PD) is the second most common neurodegenerative disease featured to mitochondrial dysfunction in neuronal cells. Dynamin-related protein 1 (Drp1) is an important regulator of mitochondrial fission and subsequent mitophagy. Mangif
Autor:
Si-Tong Feng, Nai-Hong Chen, Xiao-Le Wang, Zhen-Zhen Wang, Zhi-Peng Li, Yu-He Yuan, Ya-Ting Wang, Yi Zhang
Publikováno v:
The American journal of Chinese medicine. 49(3)
Depression is a common neuropsychiatric symptom of Parkinson’s disease (PD), resulting in a lower quality of life and cognitive impairment in PD patients. Traditional Chinese medicine (TCM) formulas have been widely used in neurodegenerative diseas
Publikováno v:
Journal of Ethnopharmacology. 287:114960
Danzhi-Xiaoyao-San (DXS), as a canonical Chinese medicine formula, possessing the functions of the soothing liver, invigorating spleen, clearing heat, and cooling blood, has been widely used for the treatment of depression.This systematic review and
Publikováno v:
Pharmacological research. 165
Neurodegenerative diseases (e.g., Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis) commonly characterized by the gradual loss of neurons have a seriously bad impact on motor and cognitive abilities of