Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Si-Shang Li"'
Autor:
Mei‐Yi Yan, Haifeng Li, Yun‐Mo Qu, Si‐Shang Li, Dandan Zheng, Xiao‐Peng Guo, Zhaojun Wu, Jie Lu, Yu Pang, Weimin Li, Jian Yang, Lingjun Zhan, Yi‐Cheng Sun
Publikováno v:
Advanced Science, Vol 11, Iss 39, Pp n/a-n/a (2024)
Abstract Tuberculosis (TB), the leading cause of death from bacterial infections worldwide, results from infection with Mycobacterium tuberculosis (Mtb). The antitubercular agents delamanid (DLM) and pretomanid (PMD) are nitroimidazole prodrugs that
Externí odkaz:
https://doaj.org/article/546649a5c07c4238ad50e9606a434aca
Autor:
Xin-Yuan Ding, Si-Shang Li, Yi-Man Geng, Mei-Yi Yan, Guo-Bao Li, Guo-Liang Zhang, Yi-Cheng Sun
Publikováno v:
Frontiers in Genome Editing, Vol 3 (2021)
Multidrug-resistant Mycobacterium tuberculosis (Mtb) infection seriously endangers global human health, creating an urgent need for new treatment strategies. Efficient genome editing tools can facilitate identification of key genes and pathways invol
Externí odkaz:
https://doaj.org/article/75994ec9eeba4a85a9eb8d6c2919e600
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT New tools for genetic manipulation of Mycobacterium tuberculosis are needed for the development of new drug regimens and vaccines aimed at curing tuberculosis infections. Clustered regularly interspaced short palindromic repeat (CRISPR)–CR
Externí odkaz:
https://doaj.org/article/d5efd17612704f668563a19bea374a8f
Autor:
Song Xue, Jian Ma, Si-Shang Li, Shuxuan Fan, YiChun Cai, Jiahao Li, Xiang Fu, ZiXin Deng, Qiu Hong Sun, Yi-Cheng Sun, Wei Ma
Publikováno v:
Microbial Drug Resistance. 28:1057-1064
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edabc045201637258a038a82c71ec960
https://doi.org/10.1089/mdr.2021.0450
https://doi.org/10.1089/mdr.2021.0450
Autor:
Mei-Yi Yan, Dandan Zheng, Si-Shang Li, Xin-Yuan Ding, Chun-Liang Wang, Xiao-Peng Guo, Lingjun Zhan, Qi Jin, Jian Yang, Yi-Cheng Sun
Publikováno v:
Science Advances. 8
CRISPR screening, including CRISPR interference (CRISPRi) and CRISPR-knockout (CRISPR-KO) screening, has become a powerful technology in the genetic screening of eukaryotes. In contrast with eukaryotes, CRISPR-KO screening has not yet been applied to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63ffae696f4c012174f79186ebf8b882
https://doi.org/10.1126/sciadv.add5907
https://doi.org/10.1126/sciadv.add5907
Publikováno v:
mBio, Vol 11, Iss 1, p e02364-19 (2020)
mBio
mBio, Vol 11, Iss 1 (2020)
mBio
mBio, Vol 11, Iss 1 (2020)
The global health impact of M. tuberculosis necessitates the development of new genetic tools for its manipulation, to facilitate the identification and characterization of novel drug targets and vaccine candidates. Clustered regularly interspaced sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68f10ae0e46da7677c088c5b31f256f
https://doaj.org/article/59173386e1284a89a71b6357fe709683
https://doaj.org/article/59173386e1284a89a71b6357fe709683