Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Si-Pei Wu"'
Autor:
Hai‐Yan Tu, Kai Yin, Xiaotian Zhao, E‐E Ke, Si‐Pei Wu, Yang‐Si Li, Mei‐Mei Zheng, Si‐Yang Maggie Liu, Chong‐Rui Xu, Yue‐Li Sun, Jia‐Xin Lin, Xiao‐Yan Bai, Yi‐Chen Zhang, Qing Zhou, Jin‐Ji Yang, Wen‐Zhao Zhong, Bing‐Chao Wang, Xu‐Chao Zhang, Dongqin Zhu, Lingling Yang, Qiuxiang Ou, Yi‐Long Wu
Publikováno v:
Molecular Oncology, Vol 17, Iss 8, Pp 1581-1594 (2023)
The efficacy of immunotherapy in advanced HER2‐mutated non‐small‐cell lung cancer (NSCLC) remains incomprehensively studied. A total of 107 NSCLC patients with de novo HER2 mutations were retrospectively studied at Guangdong Lung Cancer Institu
Externí odkaz:
https://doaj.org/article/d5aadd22e14b45079cd59c661d0f474c
Autor:
Hong‐xia Tian, Zhi‐hong Chen, Guang‐Ling Jie, Zhen Wang, Hong‐hong Yan, Si‐pei Wu, Shui‐lian Zhang, Dan‐xia Lu, Xu‐chao Zhang, Yi‐long Wu
Publikováno v:
Cancer Medicine, Vol 12, Iss 1, Pp 396-406 (2023)
Abstract Objective NF1 is a tumor suppressor gene that encodes the neurofibromin protein and negatively regulates Ras signaling. This study was aimed to investigate the molecular, clinical characteristics, and prognostic features of NF1 gene in EGFR
Externí odkaz:
https://doaj.org/article/e5f7395017c04009a1b841fdf49f70cf
Autor:
Hong‐xia Tian, Zhi‐hong Chen, Guang‐Ling Jie, Zhen Wang, Hong‐hong Yan, Si‐pei Wu, Shui‐lian Zhang, Dan‐xia Lu, Xu‐chao Zhang, Yi‐long Wu
Publikováno v:
Cancer Medicine. 12:396-406
NF1 is a tumor suppressor gene that encodes the neurofibromin protein and negatively regulates Ras signaling. This study was aimed to investigate the molecular, clinical characteristics, and prognostic features of NF1 gene in EGFR mutant lung cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eed7f1f9e53b334e4d54d80a3b77d80d
https://doi.org/10.1002/cam4.4925
https://doi.org/10.1002/cam4.4925
Autor:
Yi-long Wu, Chong-rui Xu, Si-yang Liu, Si-pei Wu, Ben-yuan Jiang, Zhi-hong Chen, Bin Gan, Bin-chao Wang, Xue-ning Yang, Zheng Wang, Zhen Wang, Huajun Chen, Hongfei Gao, Zhi Xie, Qi Zhang, Shannon Chuai, Wen-Zhao Zhong, Han Han-Zhang, Zhenfan Yang, Qing Zhou, Yu Bai, Lan-ying Gou, Jian Su, Zhou Zhang, Xu-chao Zhang, Jin-ji Yang, Anna Li
A and C. NIH3T3 cells harboring either mouse MET Y1228H or mouse MET D1226N were treated with savolitinib (A) or BMS777607 (C) at indicated concentrations. Viable cells were measured after 72 hours of treatment. Error bars represent standard deviatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::745ab64913934714af7793343d826270
https://doi.org/10.1158/1078-0432.22463064.v1
https://doi.org/10.1158/1078-0432.22463064.v1
Autor:
Yi-Long Wu, Si-Pei Wu, Ri-Qiang Liao, Li-Xu Yan, Hao-Ran Zhai, Hong-Hong Yan, Jia-Xin Lin, Xue-Ning Yang, Jin-Ji Yang, Qing Zhou, Yue-Li Sun, Hua-Jun Chen, Hai-Yan Tu, Si-Yang Liu, Zhi Xie, Jian Su, Xu-Chao Zhang, Wen-Zhao Zhong, Zhong-Yi Dong
Purpose: Although clinical studies have shown promise for targeting programmed cell death protein-1 (PD-1) and ligand (PD-L1) signaling in non–small cell lung cancer (NSCLC), the factors that predict which subtype patients will be responsive to che
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286a6a87e9257d8b063764d1063b4881
https://doi.org/10.1158/1078-0432.c.6524997
https://doi.org/10.1158/1078-0432.c.6524997
Autor:
Yi-Long Wu, Si-Pei Wu, Ri-Qiang Liao, Li-Xu Yan, Hao-Ran Zhai, Hong-Hong Yan, Jia-Xin Lin, Xue-Ning Yang, Jin-Ji Yang, Qing Zhou, Yue-Li Sun, Hua-Jun Chen, Hai-Yan Tu, Si-Yang Liu, Zhi Xie, Jian Su, Xu-Chao Zhang, Wen-Zhao Zhong, Zhong-Yi Dong
Analysis of GC>TA transversion in four groups compared common mutations (TP53/KRAS/EGFR/STK11) with corresponding wild type.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95abb642c14e214fb41930b6e43614ef
https://doi.org/10.1158/1078-0432.22462080.v1
https://doi.org/10.1158/1078-0432.22462080.v1
Autor:
Yi-long Wu, Chong-rui Xu, Si-yang Liu, Si-pei Wu, Ben-yuan Jiang, Zhi-hong Chen, Bin Gan, Bin-chao Wang, Xue-ning Yang, Zheng Wang, Zhen Wang, Huajun Chen, Hongfei Gao, Zhi Xie, Qi Zhang, Shannon Chuai, Wen-Zhao Zhong, Han Han-Zhang, Zhenfan Yang, Qing Zhou, Yu Bai, Lan-ying Gou, Jian Su, Zhou Zhang, Xu-chao Zhang, Jin-ji Yang, Anna Li
A-B. Female nu/nu athymic nude mice bearing MET mY1228H (A) and MET mY1226N (B) were treated with increasing dose of XL184 at 0mg/kg/d, 5mg/kg/d, 20mg/kg/d or 60mg/kg/d. Dose-dependent inhibition was observed for both mutations (Non-linear mixed effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96440410d37e6d246a38f0bb3d955699
https://doi.org/10.1158/1078-0432.22463061
https://doi.org/10.1158/1078-0432.22463061
Autor:
Yi-Long Wu, Si-Pei Wu, Ri-Qiang Liao, Li-Xu Yan, Hao-Ran Zhai, Hong-Hong Yan, Jia-Xin Lin, Xue-Ning Yang, Jin-Ji Yang, Qing Zhou, Yue-Li Sun, Hua-Jun Chen, Hai-Yan Tu, Si-Yang Liu, Zhi Xie, Jian Su, Xu-Chao Zhang, Wen-Zhao Zhong, Zhong-Yi Dong
Demographics and clinical characteristics of 93 ADC patients according to PD-L1 expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c4f95842ce27448265200b2c7fbaff
https://doi.org/10.1158/1078-0432.22462068.v1
https://doi.org/10.1158/1078-0432.22462068.v1
Autor:
Yi-long Wu, Chong-rui Xu, Si-yang Liu, Si-pei Wu, Ben-yuan Jiang, Zhi-hong Chen, Bin Gan, Bin-chao Wang, Xue-ning Yang, Zheng Wang, Zhen Wang, Huajun Chen, Hongfei Gao, Zhi Xie, Qi Zhang, Shannon Chuai, Wen-Zhao Zhong, Han Han-Zhang, Zhenfan Yang, Qing Zhou, Yu Bai, Lan-ying Gou, Jian Su, Zhou Zhang, Xu-chao Zhang, Jin-ji Yang, Anna Li
Schematic diagram of clonal evolution of P02 and P04. P02 carried baseline EGFR L858R and subsequently developed MET amplification at PD after EGFR-TKI exposure. After swithiching to EGFR-TKI plus MET-TKI, this patient developed MET Y1248H and D1246N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f926b91e5d47dd127a1c4646ed2f88
https://doi.org/10.1158/1078-0432.22463067.v1
https://doi.org/10.1158/1078-0432.22463067.v1
Autor:
Yi-long Wu, Chong-rui Xu, Si-yang Liu, Si-pei Wu, Ben-yuan Jiang, Zhi-hong Chen, Bin Gan, Bin-chao Wang, Xue-ning Yang, Zheng Wang, Zhen Wang, Huajun Chen, Hongfei Gao, Zhi Xie, Qi Zhang, Shannon Chuai, Wen-Zhao Zhong, Han Han-Zhang, Zhenfan Yang, Qing Zhou, Yu Bai, Lan-ying Gou, Jian Su, Zhou Zhang, Xu-chao Zhang, Jin-ji Yang, Anna Li
Kaplan-Meire plot of progression-free survival of patients with T790M mutation prior to MET-TKI treatment (blue) or without (red). Statistical significance was assessed using student's t-test (p=0.15)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd372c2a02ac685be89db7dc4fb5a4fd
https://doi.org/10.1158/1078-0432.22463070
https://doi.org/10.1158/1078-0432.22463070