Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Si-Li Zheng"'
Publikováno v:
Stroke and Vascular Neurology, Vol , Iss
The use of biologics in various diseases has dramatically increased in recent years. Stroke, a cerebrovascular disease, is the second most common cause of death, and the leading cause of disability with high morbidity worldwide. For biologics applied
Externí odkaz:
https://doaj.org/article/80ea9d6f6d8b4d99a91a958b4c34c230
Autor:
Tian-ying Xu, Sheng-li Qing, Jing-xin Zhao, Jie Song, Zhu-wei Miao, Jia-xin Li, Feng-yan Yang, Huan-yu Zhao, Si-li Zheng, Zhi-yong Li, Shu-na Wang, Chao-yu Miao
Publikováno v:
Acta Pharmacologica Sinica.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fc8e187c7840bbf82e1a52b57d28d49
https://doi.org/10.1038/s41401-023-01090-x
https://doi.org/10.1038/s41401-023-01090-x
Autor:
Chao-Yu Miao, Si-Li Zheng, Dong-Sheng Wang, Xin Dong, Yun-Feng Guan, Qi Qi, Wen-Jun Hu, Chen Hong, Chuan Zhang
Publikováno v:
Current pharmaceutical biotechnology.
Objective: This study determined for the first time the distribution of intravenous nicotinamide mononucleotide (NMN) and its metabolite nicotinamide adenine dinucleotide (NAD) in normal and ischemic stroke mice, examined the therapeutic effect of NM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::276e814b26f646cd6fa396a90d9a3e46
https://pubmed.ncbi.nlm.nih.gov/35593333
https://pubmed.ncbi.nlm.nih.gov/35593333
Publikováno v:
Acta Pharmacol Sin
Dyslipidemia is a risk factor for cardiovascular diseases and type 2 diabetes. Several adipokines play important roles in modulation of blood lipids. Metrnl is a recently identified adipokine, and adipose Metrnl participates in regulation of blood tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::346f6d89e7ff9c243067e800ec8ef571
https://doi.org/10.1038/s41401-020-0368-8
https://doi.org/10.1038/s41401-020-0368-8
Autor:
Pei Wang, Xia Hua, Si-Li Zheng, Yuan-Yuan Kong, Chun-Chun Wei, Guo-Qiang Li, Ming-He Cheng, Chao-Yu Miao
Publikováno v:
British Journal of Pharmacology. 174:3823-3836
Background and Purpose Tissue plasminogen activator (tPA) is the only approved pharmacological therapy for acute brain ischemia; however, a major limitation of tPA is the haemorrhagic transformation followed by tPA treatment. Here, we determine wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f2c68d2ee491753c8feb5928cc703ba
https://doi.org/10.1111/bph.13979
https://doi.org/10.1111/bph.13979
Publikováno v:
Acta Pharmacologica Sinica. 37:1458-1466
Metrnl is a novel secreted protein, but its physiological roles remain elusive. In this study, we investigated the tissue expression pattern of Metrnl in humans and explored its possible physiological role in the tissues with most highly expressed le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b53d118f50b5fc2c4acac7f9d313e2f
https://doi.org/10.1038/aps.2016.70
https://doi.org/10.1038/aps.2016.70
Autor:
Chun-Chun, Wei, Yuan-Yuan, Kong, Xia, Hua, Guo-Qiang, Li, Si-Li, Zheng, Ming-He, Cheng, Pei, Wang, Chao-Yu, Miao
Publikováno v:
British journal of pharmacology. 174(21)
Tissue plasminogen activator (tPA) is the only approved pharmacological therapy for acute brain ischaemia; however, a major limitation of tPA is the haemorrhagic transformation that follows tPA treatment. Here, we determined whether nicotinamide mono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::07708bf014df4d3f4ed07deac038302f
https://pubmed.ncbi.nlm.nih.gov/28812311
https://pubmed.ncbi.nlm.nih.gov/28812311
Publikováno v:
Acta Pharmacologica Sinica
Secreted proteins play critical roles in physiological and pathological processes and can be used as biomarkers and therapies for aging and disease. Metrnl is a novel secreted protein homologous to the neurotrophin Metrn. But this protein, unlike Met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33f9042bcc266088ca95789af326c73b
https://pubmed.ncbi.nlm.nih.gov/27063217
https://pubmed.ncbi.nlm.nih.gov/27063217
Autor:
Yi Qu, Zhi-Yong Li, Mao-bing Fan, Chao-Yu Miao, Pei Wang, Si-Li Zheng, Jian Xu, Jie Song, Yun-Feng Guan
Publikováno v:
Diabetes. 64(12)
Adipokines play important roles in metabolic homeostasis and disease. We have recently identified a novel adipokine Metrnl, also known as Subfatin, for its high expression in subcutaneous fat. Here, we demonstrate a prodifferentiation action of Metrn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6092f0a28c6cc489e0e3b2b29612fdef
https://pubmed.ncbi.nlm.nih.gov/26307585
https://pubmed.ncbi.nlm.nih.gov/26307585
Autor:
Zhi-Yong Li, Jie Song, Si-Li Zheng, Mao-Bing Fan, Yun-Feng Guan, Yi Qu, Jian Xu, Pei Wang, Chao-Yu Miao, Li, Zhi-Yong, Song, Jie, Zheng, Si-Li, Fan, Mao-Bing, Guan, Yun-Feng, Qu, Yi, Xu, Jian, Wang, Pei, Miao, Chao-Yu
Publikováno v:
Diabetes; Dec2015, Vol. 64 Issue 12, p4011-4022, 12p, 8 Graphs