Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Si-Han Zhang"'
Autor:
Qi-Dong Xia, Jian-Xuan Sun, Zhi-Peng Yao, Jun-Lin Lu, Chen-Qian Liu, Jin-Zhou Xu, Ye An, Meng-Yao Xu, Si-Han Zhang, Xing-Yu Zhong, Na Zeng, Si-Yang Ma, Hao-Dong He, Heng-Long Hu, Jia Hu, Yi Lu, Bing Li, Yao-Bing Chen, Zheng Liu, Shao-Gang Wang
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-13 (2024)
Abstract We aimed to investigate the genomic and tumor microenvironmental (TME) profiles in non-muscle invasive bladder cancer (NMIBC) and explore potential predictive markers for Bacillus Calmette–Guérin (BCG) treatment response in high-risk NMIB
Externí odkaz:
https://doaj.org/article/dc4bb2721ff94fe1a81803c0f0ae0d34
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Focal therapy, a minimally invasive strategy for localized prostate cancer, has been widely employed in the targeted treatment of localized prostate cancer in recent years. We analyzed 1312 relevant papers from the last decade using Web of S
Externí odkaz:
https://doaj.org/article/2b136b953f114e8485def631023de455
Autor:
Si-Han Zhang, Yaowu Su, Mengzhu Zheng, Na Zeng, Jian-Xuan Sun, Jin-Zhou Xu, Chen-Qian Liu, Shao-Gang Wang, Yirong Zhou, Qi-Dong Xia
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 180, Iss , Pp 117485- (2024)
The combination of androgen signaling inhibitors and PARP inhibitors has shown promising results in clinical trials for the treatment of castration-resistant prostate cancer (CRPC). Multi-target inhibitors can inhibit tumors through different pathway
Externí odkaz:
https://doaj.org/article/fdb2d9b4d5f140cd8b930a2a719c65b8
Autor:
Si-Han Zhang, Na Zeng, Jin-Zhou Xu, Chen-Qian Liu, Meng-Yao Xu, Jian-Xuan Sun, Ye An, Xing-Yu Zhong, Lin-Tao Miao, Shao-Gang Wang, Qi-Dong Xia
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 180, Iss , Pp 117584- (2024)
Proteolysis Targeting Chimera (PROTAC) is an emerging and evolving technology based on targeted protein degradation (TPD). Small molecule PROTACs have shown great efficacy in degrading disease-specific proteins in preclinical and clinical studies, bu
Externí odkaz:
https://doaj.org/article/2a2bf195cb1843d0a540156ade3c2d46
Autor:
Meng-Yao Xu, Na Zeng, Chen-Qian Liu, Jian-Xuan Sun, Ye An, Si-Han Zhang, Jin-Zhou Xu, Xing-Yu Zhong, Si-Yang Ma, Hao-Dong He, Jia Hu, Qi-Dong Xia, Shao-Gang Wang
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-23 (2024)
Abstract Enhanced cellular therapy has emerged as a novel concept following the basis of cellular therapy. This treatment modality applied drugs or biotechnology to directly enhance or genetically modify cells to enhance the efficacy of adoptive cell
Externí odkaz:
https://doaj.org/article/8ad6007f8ff74808b59c24c681dc65df
Autor:
Meng-Yao Xu, Zhi-Yu Xia, Jian-Xuan Sun, Chen-Qian Liu, Ye An, Jin-Zhou Xu, Si-Han Zhang, Xing-Yu Zhong, Na Zeng, Si-Yang Ma, Hao-Dong He, Shao-Gang Wang, Qi-Dong Xia
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The emergence of resistance to prostate cancer (PCa) treatment, particularly to androgen deprivation therapy (ADT), has posed a significant challenge in the field of PCa management. Among the therapeutic options for PCa, radiotherapy, chemotherapy, a
Externí odkaz:
https://doaj.org/article/794a642116d4478eaed39e3690b6ce14
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 168, Iss , Pp 115806- (2023)
Androgen receptor (AR) signaling is essential in prostate cancer treatment. For many years, androgen deprivation therapy (ADT) has been primarily applied to manage advanced prostate cancer. However, most individuals with metastatic hormone-sensitive
Externí odkaz:
https://doaj.org/article/840d3f0584df48dc9bc994340041ee9a
Autor:
Si-Han Zhang, Na Zeng, Jian-Xuan Sun, Chen-Qian Liu, Jin-Zhou Xu, Meng-Yao Xu, Ye An, Xing-Yu Zhong, Si-Yang Ma, Hao-Dong He, Qi-Dong Xia, Jia Hu, Shao-Gang Wang
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e16644- (2023)
Background: Cereblon (CRBN) has emerged as a vital E3 ubiquitin ligase for Proteolysis-targeting chimera (PROTAC) design. However, few studies focus on the physiological mechanism of CRBN, and more studies are needed to explore the influence of CRBN
Externí odkaz:
https://doaj.org/article/d0a70bc1f0554f0da64992375c7f32bf
Autor:
Jin-Zhou Xu, Jian-Xuan Sun, Lin-Tao Miao, Si-Han Zhang, Wen-Jie Wang, Chen-Qian Liu, Qi-Dong Xia, Jun-Lin Lu, Peng Zhou, Yong-Man Lv, Yang Xun, Wei Guan, Lei Cui
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionUrolithiasis is one of the most common diseases for urologists and it is a heavy burden for stone formers and society. The theory of the oral–genitourinary axis casts novel light on the pathological process of genitourinary system disea
Externí odkaz:
https://doaj.org/article/ff0064154a454f3c9f8236dc6433b80b
Autor:
Qi-Dong Xia, Bo Li, Jian-Xuan Sun, Chen-Qian Liu, Jin-Zhou Xu, Ye An, Meng-Yao Xu, Si-Han Zhang, Xing-Yu Zhong, Na Zeng, Si-Yang Ma, Hao-Dong He, Yu-Cong Zhang, Wei Guan, Heng Li, Shao-Gang Wang
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundT cell immunoglobulin and ITIM domain (TIGIT) is a widely concerned immune checkpoint, which plays an essential role in immunosuppression and immune evasion. However, the role of TIGIT in normal organ tissues and renal clear cell carcinoma
Externí odkaz:
https://doaj.org/article/e1b5833590724c818692a9377361a84a