Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Si-Eun Baek"'
Autor:
Si-Eun Baek, Younghwi Kwon, Jong-Won Yoon, Hyo-Sung Kim, Jae-Yoon Yang, Dong-Seok Lee, Eunbyul Yeom
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-5 (2024)
Abstract Dorsal switch protein 1(DSP1), a mammalian homolog of HMGB1, is firstly identified as a dorsal co-repressor in 1994. DSP1 contains HMG-box domain and functions as a transcriptional regulator in Drosophila melanogaster. It plays a crucial rol
Externí odkaz:
https://doaj.org/article/073af0c87979458699cd56b70a60d49d
Publikováno v:
Bulletin of the Korean Chemical Society. 36:2494-2500
Combination of drug delivery and specific targeting has the potential for treating cancers. To achieve this goal, specific ligands targeting cancer cells and bioconjugate vehicles for drug delivery are necessary. Liposomes constitute successful drug-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed7ddb2e696eb160fac064222718ffc8
https://doi.org/10.1002/bkcs.10480
https://doi.org/10.1002/bkcs.10480
Autor:
Dong-Eun Kim, Na Ra Lee, Vinod Kasam, Shou Zhou, Do Min Lee, Yujin Jang, Kyung Bo Kim, Chang-Guo Zhan, Lin Ao, Qingquan Zhao, Kwanghyun Lee, Yan Yan Zhang, Wooin Lee, Hyunyoung Jeong, Keun Sik Kim, Si Eun Baek, Zachary Miller, Kimberly Cornish Carmony
Publikováno v:
Journal of Medicinal Chemistry. 58:2036-2041
We performed a virtual screen of ∼340 000 small molecules against the active site of proteasomes followed by in vitro assays and subsequent optimization, yielding a proteasome inhibitor with pyrazole scaffold. The pyrazole-scaffold compound display
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da7fd90ba6a20adebbd118c7167f9ca3
https://doi.org/10.1021/jm501344n
https://doi.org/10.1021/jm501344n
Autor:
Si Eun Baek, Yong-Joo Jeong, Wonhee Suh, Kyung Bo Kim, Jungwoo Choe, Yo Han Cho, Soojin Yoon, Dong-Eun Kim, H.-R. Kim
Publikováno v:
Biochemical and Biophysical Research Communications. 456:591-597
Duplex RNA harboring the 50-terminal triphosphate RNA is hypothesized to not only execute selective gene silencing via RNA interference, but also induce type I interferon (IFN) through activation of the ret- inoic acid inducible gene I (RIG-I). We ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eeaf8ff80db5f0c4e457ba24164fb9b
https://doi.org/10.1016/j.bbrc.2014.11.119
https://doi.org/10.1016/j.bbrc.2014.11.119
Autor:
Deok-Kun Oh, Si Eun Baek, Keun-Sik Kim, Dong-Eun Kim, Yong Serk Park, Sangtaek Oh, Kwanghyun Lee
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 196
To minimize the systemic toxicity prevalent to chemotherapeutics, we designed a novel anticancer drug-encapsulating liposome conjugated with an RNA aptamer specific to the prostate specific membrane antigen (PSMA), which is expressed on the surface o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0cd289f84a9dfd83da90ad17ad39837
https://pubmed.ncbi.nlm.nih.gov/25450401
https://pubmed.ncbi.nlm.nih.gov/25450401
Autor:
Miller, Zachary, Keun-Sik Kim, Do-Min Lee, Kasam, Vinod, Si Eun Baek, Kwang Hyun Lee, Yan-Yan Zhang, Lin Ao, Carmony, Kimberly, Na-Ra Lee, Shou Zhou, Qingquan Zhao, Yujin Jang, Hyun-Young Jeong, Chang-Guo Zhan, Wooin Lee, Dong-Eun Kim, Kyung Bo Kim
Publikováno v:
Journal of Medicinal Chemistry; Feb2015, Vol. 58 Issue 4, p2036-2041, 6p