Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Si Nga Wong"'
Autor:
Si Nga Wong, Jingwen Weng, Ignatius Ip, Ruipeng Chen, Richard Lakerveld, Richard Telford, Nicholas Blagden, Ian J. Scowen, Shing Fung Chow
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 300 (2022)
Formulating pharmaceutical cocrystals as inhalable dosage forms represents a unique niche in effective management of respiratory infections. Favipiravir, a broad-spectrum antiviral drug with potential pharmacological activity against SARS-CoV-2, exhi
Externí odkaz:
https://doaj.org/article/0cfc658a58ee45c7b818c8d99a5f3b77
Autor:
Si Nga Wong, Susan Wing Sze Chan, Xuexin Peng, Bianfei Xuan, Hok Wai Lee, Henry H. Y. Tong, Shing Fung Chow
Publikováno v:
Pharmaceutics, Vol 12, Iss 12, p 1209 (2020)
The kinetic entrapment of molecules in an amorphous phase is a common obstacle to cocrystal screening using rapid solvent removal, especially for drugs with a moderate or high glass-forming ability (GFA). The aim of this study was to elucidate the ef
Externí odkaz:
https://doaj.org/article/5bd00b9bc7854f498618ca4452c09468
Publikováno v:
CrystEngComm. 24:5875-5879
We herein report the successful synthesis of the first two dexamethasone cocrystals from mechanochemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4707da2e4056e25c1e3a9914e0a800c7
https://doi.org/10.1039/d2ce00758d
https://doi.org/10.1039/d2ce00758d
Publikováno v:
International Journal of Pharmaceutics. 640:122983
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::920fc9c95c77e24bf9c87abf9dfd8090
https://doi.org/10.1016/j.ijpharm.2023.122983
https://doi.org/10.1016/j.ijpharm.2023.122983
Publikováno v:
CrystEngComm. 23:7005-7038
Cocrystals are an emerging class of crystalline materials composed of two or more different molecules in the same crystal lattice that are physically connected by non-ionic and non-covalent bonds. Formulating problematic drugs into cocrystals is a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36ed98dcb5b7659e142a54cf0cabc1e6
https://doi.org/10.1039/d1ce00825k
https://doi.org/10.1039/d1ce00825k
Autor:
Jingwen Weng, Si Nga Wong, Shing Fung Chow, Ka Yee Wan, Philip Chi Lip Kwok, Albert Hee Lum Chow
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 149:238-247
While nanoparticulate drugs for deep lung delivery hold promise for particular disease treatments, their size-related physical instability and tendency of being exhaled during breathing remain major challenges to their inhaled formulation development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79c47e98c062fa3c362321748da4723e
https://doi.org/10.1016/j.ejpb.2020.02.010
https://doi.org/10.1016/j.ejpb.2020.02.010
Autor:
Yanjie Zhang, Henry H.Y. Tong, Si Nga Wong, Jingwen Weng, Bianfei Xuan, Changquan Calvin Sun, Chenguang Wang, Shing Fung Chow
Publikováno v:
Crystal Growth & Design. 20:1951-1960
The aim of this study was to design and evaluate a cocrystal capable of releasing a highly water soluble drug, isoniazid (INH), over a period of longer than several hours by forming a cocrystal wit...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff52ec37776bc96daf5760774e698a4d
https://doi.org/10.1021/acs.cgd.9b01619
https://doi.org/10.1021/acs.cgd.9b01619
Autor:
Si Nga Wong, Ruipeng Chen, Bianfei Xuan, Changquan Calvin Sun, Jingwen Weng, Xiaoyan Xu, Shing Fung Chow, Chenguang Wang, Philip Chi Lip Kwok, Richard Lakerveld
Publikováno v:
Crystal Growth & Design. 19:2736-2745
Cocrystallization represents an emerging approach to tackle the issues associated with pharmaceutical product performance and processing, owing to its capability of modifying a variety of physicochemical properties. In this study, we sought to modify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::391092e0a4cbf4a91e2f552ac21c2ee6
https://doi.org/10.1021/acs.cgd.8b01873
https://doi.org/10.1021/acs.cgd.8b01873
Autor:
Hok Wai Lee, Xuexin Peng, Henry H.Y. Tong, Susan Wing Sze Chan, Bianfei Xuan, Si Nga Wong, Shing Fung Chow
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 12, Iss 1209, p 1209 (2020)
Volume 12
Issue 12
Pharmaceutics, Vol 12, Iss 1209, p 1209 (2020)
Volume 12
Issue 12
The kinetic entrapment of molecules in an amorphous phase is a common obstacle to cocrystal screening using rapid solvent removal, especially for drugs with a moderate or high glass-forming ability (GFA). The aim of this study was to elucidate the ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79ae1a3c62bd478b8b07d8d9b9150c53
http://europepmc.org/articles/PMC7764899
http://europepmc.org/articles/PMC7764899
Publikováno v:
Molecular pharmaceutics. 18(2)
Retinal diseases, such as age-related macular degeneration and diabetic retinopathy, are the leading causes of blindness worldwide. The mainstay of treatment for these blinding diseases remains to be surgery, and the available pharmaceutical therapie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77ae35f8eff7e7a8998706f24bff65d
https://pubmed.ncbi.nlm.nih.gov/32501716
https://pubmed.ncbi.nlm.nih.gov/32501716