Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Si Guang Xu"'
Autor:
Guo Yang He, Li Yuan Qu, Hui Fang Zhu, Ming Yong Wang, Mo Zhang, Zhi Qing Yuan, Zhe Ying Zhang, Na Li, Ying Song, Si Guang Xu, Yongzhen Li, Man Man Lu
Publikováno v:
Journal of Cancer
Background: Paclitaxel plays a pivotal role in the chemotherapy of breast cancer, but resistance to this drug is an important obstacle in the treatment. It is reported that microRNA-152-3p (miR-152-3p) is involved in tamoxifen resistance in breast ca
Autor:
Liu Yang, Jiong Wu, San Jian Yu, Xia Ying Kuang, Gen Hong Di, Guang Yu Liu, Si Guang Xu, Zhi Ming Shao, Qi Hong
Publikováno v:
Molecular Medicine Reports
Transgelin 2 (TAGLN2) is a cytoskeletal protein of the calponin family. Abnormal expression of TAGLN2 was observed in various types of cancer. Our previous study reported that TAGLN2 expression was reduced in lymph node‑positive breast cancer patie
Publikováno v:
Journal of Cancer
The epithelial Na+ channel/degenerin (ENaC/DEG) superfamily, including the acid-sensing ion channels (ASICs), is characterized by a high degree of similarity in structure but highly diverse in physiological functions. These ion channels have been sho
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 136:1545-1556
Distant metastasis represents the major lethal cause of breast cancer. To understand the molecular mechanisms of breast cancer metastasis and identify markers with metastatic potential, we established a highly metastatic variant of parental MDA-MB-23
Publikováno v:
Breast Cancer Research and Treatment. 124:39-48
Overexpression of MDR1 in breast cancer remains a major cause for the failure of chemotherapy. In the present report, we find UHRF1 plays an important role in inhibiting MDR1 promoter activity by directly binding to the MDR1 promoter. Knockdown of UH
Publikováno v:
Breast cancer research and treatment. 123(2)
BRCA1 is closely related to the pathogenesis of breast cancer, BRCA1 mRNA is reduced in sporadic breast cancer cells despite the lack of mutations. In the present report, we found that overexpression of UHRF1 (ubiquitin-like, containing PHD and RING