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pro vyhledávání: '"Si Cave"'
Autor:
Carl W. Decker, Jerome Garcia, Kristelle Gatchalian, Deronisha Arceneaux, Clarice Choi, Si Cave, Derick Han, Jeniffer B. Hernandez
Publikováno v:
Biochemistry and Biophysics Reports, Vol 24, Iss , Pp 100824- (2020)
Mitochondria oscillate along a morphological continuum from fragmented individual units to hyperfused tubular networks. Their position at the junction of catabolic and anabolic metabolism couples this morphological plasticity, called mitochondrial dy
Externí odkaz:
https://doaj.org/article/abe5071228c34182bdd10fd7b701bb8e
Autor:
Jeniffer B Hernandez, Si Cave, Qiyuan Yang, Carl Decker, Jack Swanson, Ezra Wiater, Ye Zheng, Marc Montminy
Publikováno v:
The Journal of Immunology. 206:53.02-53.02
GPR65 has been shown to be a critical regulator of Th17 pathogenicity. Loss of GPR65 in mice results in a decrease in Th17 cells and reduced susceptibility to a mouse model of multiple sclerosis. The CREB/CRTC2 pathway has emerged as an important reg
Autor:
Jeniffer B Hernandez, Si Cave, Carl Decker, Jack Swanson, Qiyuan Yang, Ye Zheng, Marc Montminy
Publikováno v:
The Journal of Immunology. 204:76.1-76.1
The cAMP response element-binding (CREB) protein has emerged as an important regulator of immune function. We have previously shown that CREB, along with its co-activator CRTC2, modulates autoimmune disease by promoting differentiation of the pro-inf
Publikováno v:
The Journal of Immunology. 200:171.16-171.16
Th17 cells have quickly become a paradigm of intense research interest, owing in part to their central role in mediating tissue-immune system communication, their demonstrable anti-tumor capacity, and their involvement in the pathogenesis of several
Autor:
Jeniffer B Hernandez, Si Cave
Publikováno v:
The Journal of Immunology. 198:223.2-223.2
The CREB/CRTC2 pathway has emerged as an important regulator of immune function. We have previously shown that the CREB/CRTC2 pathway modulates autoimmune disease by promoting differentiation of the pro-inflammatory T cell, Th17. Although Th17 cells