Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Si‐Hua Hou"'
Publikováno v:
Molecules, Vol 28, Iss 17, p 6193 (2023)
Natural products play a key role in innovative drug discovery. To explore the potential application of natural products and their analogues in pharmacology, total synthesis is a key tool that provides natural product candidates and synthetic analogue
Externí odkaz:
https://doaj.org/article/1ba33e37b14c4624876034492bcaf854
Publikováno v:
Journal of the American Chemical Society. 144:22159-22169
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::682c39e97dc51fd516d754902142dd7d
https://doi.org/10.1021/jacs.2c09814
https://doi.org/10.1021/jacs.2c09814
Autor:
Quan‐Zhe Li, Si‐Hua Hou, Jun‐Chen Kang, Peng‐Fei Lian, Yu Hao, Chao Chen, Jia Zhou, Tong‐Mei Ding, Shu‐Yu Zhang
Publikováno v:
Angewandte Chemie. 134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ff6169978196092b0201ca8219cb7f
https://doi.org/10.1002/ange.202207088
https://doi.org/10.1002/ange.202207088
Publikováno v:
Angew Chem Int Ed Engl
Herein, we describe the development of a deconstructive strategy for the first asymmetric synthesis of (−)-thebainone A, capitalized on an enantioselective C−C bond activation and a C−O bond cleavage reaction. The Rh-catalyzed asymmetric ‘cut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85367bba4329daa1a9264fb08927b687
https://doi.org/10.1002/anie.202103553
https://doi.org/10.1002/anie.202103553
Publikováno v:
Angew Chem Int Ed Engl
To show the synthetic utility of the catalytic C-C activation of less strained substrates, described here are the collective and concise syntheses of the natural products (-)-microthecaline A, (-)-leubehanol, (+)-pseudopteroxazole, (+)-seco-pseudopte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9e46460b7ab271e38a2c21fadfb573
https://doi.org/10.1002/ange.201915821
https://doi.org/10.1002/ange.201915821
Autor:
Jun-Chen Kang, Shu-Yu Zhang, Si-Hua Hou, Fu-Xin Tan, Zhi-Gang Ma, Guo-Dong Zhu, Jia Zhou, Wei Jiang, Le Wang
Publikováno v:
Organic Letters. 21:8662-8666
A versatile dual H-bonds and π-π interaction strategy that enables enantioselective remote C6-selective C-H functionalization of 2,3-disubstituted indoles was first reported. The N-H bond of indole was pivotal to achieve the C6 functionalization wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04922aa7a93de103fa6421361fdef837
https://doi.org/10.1021/acs.orglett.9b03276
https://doi.org/10.1021/acs.orglett.9b03276
Autor:
Si-Hua Hou, He-Yuan Bai, Xun-Hui Wang, Yan-Yan Ma, Quan-Zhe Li, Tong-Mei Ding, Shu-Yu Zhang, Deng-Gao Zhao
Publikováno v:
Synthesis. 51:2697-2704
A simple and efficient protocol for para-selective C–H amination of 1-naphthylamide derivatives under silver catalysis is described. This reaction system could proceed without the help of directing group and a broad range of substrates were proved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9aa85731356ec22c1ff4ca30b3502d0
https://doi.org/10.1055/s-0037-1610705
https://doi.org/10.1055/s-0037-1610705
Publikováno v:
J Am Chem Soc
Synthesis of bridged scaffolds via Type II cyclization constitutes substantial challenges due to the intrinsic ring strain accumulated in reaction transition states. Catalytic enantioselective Type II-cyclization methods are even rarer. Here, we desc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010c77abfec61613bdaa06ca5e09db32
https://pubmed.ncbi.nlm.nih.gov/32619351
https://pubmed.ncbi.nlm.nih.gov/32619351
Publikováno v:
Organic letters. 21(8)
A method of SPINOL-derived chiral phosphoric acid catalyzed asymmetric intermolecular N-hydroxyalkylation of multisubstituted indoles with ethyl glyoxalates is described in this report. This protocol provides an alternative, convenient, and direct st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04da1ee04a1665e3398fc40f5b00bd97
https://pubmed.ncbi.nlm.nih.gov/30969130
https://pubmed.ncbi.nlm.nih.gov/30969130
Publikováno v:
Chemical Communications. 52:13151-13154
An efficient and convenient method has been developed to achieve direct silylation of unactivated remote primary or secondary C(sp3)–H bonds to form C–Si bonds with hexamethyldisilane (HMDS). This method highlights the emerging strategy to transf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2d4d1f3ce273e686062b4192e395d97
https://doi.org/10.1039/c6cc07885k
https://doi.org/10.1039/c6cc07885k