Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Shyuichiro Matsubara"'
Autor:
Sho Kitamoto, Seiya Yokoyama, Michiyo Higashi, Norishige Yamada, Shyuichiro Matsubara, Sonshin Takao, Surinder K Batra, Suguru Yonezawa
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44108 (2012)
MUC17 is a type 1 membrane-bound glycoprotein that is mainly expressed in the digestive tract. Recent studies have demonstrated that the aberrant overexpression of MUC17 is correlated with the malignant potential of pancreatic ductal adenocarcinomas
Externí odkaz:
https://doaj.org/article/0e6e15c31e8c484fb19e13fba96cd34e
Publikováno v:
Human cell. 33(4)
CD133 expression in pancreatic cancer correlates with poor prognosis and increased metastasis. CD133+ pancreatic cancer cells exhibit cancer stem cell (CSC)-like properties. We established a CD133+ cell-rich subline from Capan-1 pancreatic cancer cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29fabf6dedb4675f359710632aff2362
https://pubmed.ncbi.nlm.nih.gov/32851605
https://pubmed.ncbi.nlm.nih.gov/32851605
Autor:
Shyuichiro Matsubara1, Qiang Ding1, Yumi Miyazaki1, Taisaku Kuwahata2, Koichiro Tsukasa1, Sonshin Takao1 sonshin@m2.kufm.kagoshima-u.ac.jp
Publikováno v:
Scientific Reports. 11/15/2013, p1-10. 10p.
Autor:
Sonshin Takao, Yumi Miyazaki, Qiang Ding, Koichiro Tsukasa, Shyuichiro Matsubara, Taisaku Kuwahata
Publikováno v:
Scientific Reports
Pancreatic cancer is characterized by near-universal mutations in KRAS. The mammalian target of rapamycin (mTOR), which functions downstream of RAS, has divergent effects on stem cells. In the present study, we investigated the significance of the mT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee84d12777f25f83f1bcfa3d213d16de
http://hdl.handle.net/10232/25578
http://hdl.handle.net/10232/25578
Autor:
Yumi Miyazaki, Shoji Natsugoe, Qiang Ding, Sonshin Takao, Koichiro Tsukasa, Shyuichiro Matsubara
Publikováno v:
Human cell. 29(3)
Pancreatic cancer is a deadly disease with a poor prognosis. Recently, miRNAs have been reported to be abnormally expressed in several cancers and play a role in cancer development and progression. However, the role of miRNA in cancer stem cells rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c33db59235d69551fa2b406856068bf0
https://pubmed.ncbi.nlm.nih.gov/26965588
https://pubmed.ncbi.nlm.nih.gov/26965588
Pancreatic cancer stem cells: regulatory networks in the tumor microenvironment and targeted therapy
Publikováno v:
Journal of Hepato-Biliary-Pancreatic Sciences. 19:614-620
Recent evidence has demonstrated that the existence of a cancer stem cell (CSC) subset in a solid tumor is responsible for the progression and relapse of cancer as well as its resistance to current therapies. Over the past decade, CSC research on pan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a31a07166d18636aa0ff4755e6b46b1
https://doi.org/10.1007/s00534-012-0547-1
https://doi.org/10.1007/s00534-012-0547-1
Autor:
Asuka Nakayama, Shyuichiro Matsubara, Takaaki Yokomine, Mitsutoshi Yoshida, Mariko Shinohara, Eri Akasaka, Sonshin Takao, Masahiro Sato
Publikováno v:
Cloning and Stem Cells. 9:523-534
Porcine embryonic fibroblasts (PEF) are important as donor cells for nuclear transfer for generation of genetically modified pigs. In this study, we determined an optimal protocol for transfection of PEF with the Amaxa Nucleofection system, which dir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79caa1e5091a53b379d9f065844319c8
https://doi.org/10.1089/clo.2007.0021
https://doi.org/10.1089/clo.2007.0021
Autor:
Makoto Yoshimitsu, Yumi Miyazaki, Qiang Ding, Sonshin Takao, Koichiro Tsukasa, Shyuichiro Matsubara
Publikováno v:
Human cell. 28(4)
CD133-positive pancreatic cancer is correlated with unfavorable survival despite current development of therapy. Slug acts as a master regulator of epithelial-mesenchymal transition (EMT) which is the essential process in cancer progression. The aim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf29b9a0f7c0f41b93c5baa7f6eaac3d
https://pubmed.ncbi.nlm.nih.gov/25997702
https://pubmed.ncbi.nlm.nih.gov/25997702
Autor:
Masatoshi Tagawa, L Yu, Shyuichiro Matsubara, Katsuyuki Hamada, Kenji Kadomatsu, Masayoshi Namba, Takashi Muramatsu
Publikováno v:
European Journal of Cancer. 40:1787-1794
We examined possible application of a regulatory region of midkine (MK) gene, which is frequently upregulated in a number of human tumours but not in normal cells, to cancer gene therapy. We examined transcriptional activity of the MK genomic fragmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b02a1d6c0164949e9ae1ebf87049362
https://doi.org/10.1016/j.ejca.2004.04.014
https://doi.org/10.1016/j.ejca.2004.04.014
Autor:
Masayuki Ozawa, Shyuichiro Matsubara
Publikováno v:
Oncogene. 23:2694-2702
alpha-Catenin is an intracellular protein that associates with the carboxy-terminal region of cadherin, a cell adhesion molecule, via beta-catenin or gamma-catenin (plakoglobin). Linkage of cadherin to the cytoskeleton by catenins is required for ful
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0235413002ba5bb899ccfc8d7c8877cb
https://doi.org/10.1038/sj.onc.1207423
https://doi.org/10.1038/sj.onc.1207423