Histone chaperone Nucleophosmin regulates transcription of key genes involved in oral tumorigenesis

Autor: Parijat Senapati, Aditya Bhattacharya, Sadhan Das, Suchismita Dey, Deepthi Sudarshan, Shyla G, Jyoti Vishwakarma, Surabhi Sudevan, Ravishankar Ramachandran, Tessy Thomas Maliekal, Tapas K. Kundu

Publikováno v: Mol Cell Biol

Nucleophosmin (NPM1) is a multifunctional histone chaperone that can activate acetylation-dependent transcription from chromatin templates in vitro. p300-mediated acetylation of NPM1 has been shown to further enhance its transcription activation pote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d76a3514ef450b3bf053592a75ba796
https://doi.org/10.1096/fasebj.2022.36.s1.r4402

SSTP1, A Host Defense Peptide, Exploits the Immunomodulatory Il6 Pathway to Induce Apoptosis in Cancer Cells

Autor: Shyla G., Soumya Krishnan U., Amrutha Mohan, Geetha Shanmugam, Vineethkumar T.V., Sreekumar J., Sivakumar K.C., Dileep Vasudevan, Sai Ravi Chandra Nori, Shijulal Nelson Sathi, Sanil George, Tessy Thomas Maliekal

Background: The anticancer activities of host defense peptides (HDPs) are mainly attributed to their cell penetrating activity. Accordingly, several approaches based on machine learning, calculating the membrane pore formation ability, have been prop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::022d54ed39244d8f253f342e66bce8ad
https://doi.org/10.21203/rs.3.rs-678241/v1

Functional characterization of two novel peptides and their analogs identified from the skin secretion of Indosylvirana aurantiaca, an endemic frog species of Western Ghats, India.

Autor: Shyla, G., Vineethkumar, T. V., Arun, V., Divya, M. P., Thomas, Sabu, George, Sanil

Publikováno v: Chemoecology; Dec2019, Vol. 29 Issue 5/6, p179-187, 9p

Liver oil of pharaoh cuttlefish Sepia pharaonis Ehrenberg, 1831 as a lipid source in the feed of giant freshwater prawn, Macrobrachium rosenbergii (De Man 1879).

Autor: Shyla, G.¹, Nair, C. M.¹ naircm@hotmail.com, Salin, K. R.², Sherief, P. M.¹, Mukundan, M. K.³

Publikováno v: Aquaculture Nutrition. Jun2009, Vol. 15 Issue 3, p273-281. 9p. 9 Charts.

Identification and characterization of novel host defense peptides from the skin secretion of the fungoid frog, Hydrophylax bahuvistara (Anura: Ranidae).

Autor: Vineeth Kumar TPVK; Molecular Ecology Laboratory, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India., Asha R; Chemical Biology Laboratory, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India., Shyla G; Molecular Ecology Laboratory, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India., George S; Molecular Ecology Laboratory, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India.

Publikováno v: Chemical biology & drug design [Chem Biol Drug Des] 2018 Aug; Vol. 92 (2), pp. 1409-1418. Date of Electronic Publication: 2017 Feb 11.