Transduction of Salivary Gland Acinar Cells with a Novel AAV Vector 44.9

Autor: Giovanni Di Pasquale, Paola Perez Riveros, Muhibullah Tora, Tayyab Sheikh, Aran Son, Leyla Teos, Brigitte Grewe, William D. Swaim, Sandra Afione, Changyu Zheng, Shyh-Ing Jang, Akiko Shitara, Ilias Alevizos, Roberto Weigert, John A. Chiorini

Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 19, Iss , Pp 459-466 (2020)

The loss of salivary gland function caused by radiation therapy of the head and neck or autoimmune disease such as Sjögren’s syndrome is a serious condition that affects a patient’s quality of life. Due to the combined exocrine and endocrine fun

Externí odkaz: https://doaj.org/article/7be847276d9a4acbaec511e36b5c72eb

Targeting the Ca2+ Sensor STIM1 by Exosomal Transfer of Ebv-miR-BART13-3p is Associated with Sjögren's Syndrome

Autor: Alessia Gallo, Shyh-Ing Jang, Hwei Ling Ong, Paola Perez, Mayank Tandon, Indu Ambudkar, Gabor Illei, Ilias Alevizos

Publikováno v: EBioMedicine, Vol 10, Iss C, Pp 216-226 (2016)

Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease that is associated with inflammation and dysfunction of salivary and lacrimal glands. The molecular mechanism(s) underlying this exocrinopathy is not known, although the syndrome has

Externí odkaz: https://doaj.org/article/9fb776807b84441f915e9f6de66bffbd

Inhibition of JAK-STAT pathway corrects salivary gland inflammation and interferon driven immune activation in Sjögren's disease.

Autor: Gupta, Sarthak, Yamada, Eiko, Nakamura, Hiroyuki, Perez, Paola, Pranzatelli, Thomas J. F., Dominick, Kalie, Shyh-Ing Jang, Abed, Mehdi, Martin, Daniel, Burbelo, Peter, ChangYu Zheng, French, Ben, Alevizos, Ilias, Khavandgar, Zohreh, Beach, Margaret, Pelayo, Eileen, Walitt, Brian, Hasni, Sarfaraz, Kaplan, Mariana J., Tandon, Mayank

Publikováno v: Annals of the Rheumatic Diseases; Aug2024, Vol. 83 Issue 8, p1034-1047, 31p

Transduction of Salivary Gland Acinar Cells with a Novel AAV Vector 44.9

Autor: Ilias Alevizos, Tayyab Sheikh, Changyu Zheng, Leyla Teos, Sandra Afione, Akiko Shitara, Paola Perez Riveros, Roberto Weigert, John A. Chiorini, Muhibullah S Tora, Aran Son, William D. Swaim, Shyh-Ing Jang, Brigitte Grewe, Giovanni Di Pasquale

Publikováno v: Molecular Therapy: Methods & Clinical Development, Vol 19, Iss, Pp 459-466 (2020)
Molecular Therapy. Methods & Clinical Development

The loss of salivary gland function caused by radiation therapy of the head and neck or autoimmune disease such as Sjögren’s syndrome is a serious condition that affects a patient’s quality of life. Due to the combined exocrine and endocrine fun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635ca85b0031b553a4ae46ebe3f28466
http://www.sciencedirect.com/science/article/pii/S2329050120302102

LAMP3 induces apoptosis and autoantigen release in Sjögren’s syndrome patients

Autor: Eduardo Rocha, Noriyuki Hirata, Satoko Ishigaki, Hongen Yin, Shyh-Ing Jang, Fabiola Reis Oliveira, Toshio Odani, Hiroyuki Nakamura, Blake M. Warner, Drew G. Michael, Alfredo Ribeiro-Silva, Masayuki Noguchi, John A. Chiorini, Futoshi Suizu, Youngmi Ji, Tatsuya Atsumi, Ying-Qian Mo, Ana Carolina Fragoso Motta, Tsutomu Tanaka

Publikováno v: Scientific Reports
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)

Primary Sjögren’s syndrome (pSS) is a complex autoimmune disease characterized by dysfunction of secretory epithelia with only palliative therapy. Patients present with a constellation of symptoms, and the diversity of symptomatic presentation has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df59f25521e85f6a4621f63394f7eb57
http://europepmc.org/articles/PMC7494869