Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Shyaron Poudel"'
Autor:
Efren Garcia-Maldonado, Andrew D. Huber, Sergio C. Chai, Stanley Nithianantham, Yongtao Li, Jing Wu, Shyaron Poudel, Darcie J. Miller, Jayaraman Seetharaman, Taosheng Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Nuclear receptors are ligand-activated transcription factors that can often be useful drug targets. Unfortunately, ligand promiscuity leads to two-thirds of receptors remaining clinically untargeted. PXR is a nuclear receptor that can be act
Externí odkaz:
https://doaj.org/article/c30e189d2e734c8aad1bc9b3e758e589
Publikováno v:
International Journal of Microbiology, Vol 2019 (2019)
Nosocomial infection is the infection that has been caught in a hospital and is potentially caused by organisms that are not susceptible to antibiotics. Nosocomial infections are transmitted directly or indirectly through air and may cause different
Externí odkaz:
https://doaj.org/article/7dfd30bf8161413e8c70590e35985ce2
Publikováno v:
Drug Metabolism and Disposition. 51:228-236
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19a7f3bdd1615dbea4bd7a04235d49d0
https://doi.org/10.1124/dmd.122.000858
https://doi.org/10.1124/dmd.122.000858
Autor:
Andrew D. Huber, Wenwei Lin, Shyaron Poudel, Yongtao Li, Jayaraman Seetharaman, Darcie J. Miller, Taosheng Chen
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce4f5fdd0de0b842ec1a1ac43f4309d0
https://doi.org/10.1124/jpet.122.524030
https://doi.org/10.1124/jpet.122.524030
Autor:
Wenwei Lin, Andrew D. Huber, Shyaron Poudel, Yongtao Li, Jayaraman Seetharaman, Darcie J. Miller, Taosheng Chen
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Ligand-binding promiscuity in detoxification systems protects the body from toxicological harm but is a roadblock to drug development due to the difficulty in optimizing small molecules to both retain target potency and avoid metabolic events. Immens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61d3c89847d715fe6e44247b4f80407a
https://doi.org/10.1073/pnas.2217804120
https://doi.org/10.1073/pnas.2217804120
Publikováno v:
F1000Research. 11:1450
Background: DNA methylation, the most common epigenetic modification, is defined as the removal or addition of methyl groups to cytosine bases. Studying DNA methylation provides insight into the regulation of gene expression, transposon mobility, gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e18ee16ae26a15065d4361958f22b48
https://doi.org/10.12688/f1000research.128391.1
https://doi.org/10.12688/f1000research.128391.1
Publikováno v:
International Journal of Microbiology, Vol 2019 (2019)
International Journal of Microbiology
International Journal of Microbiology
Nosocomial infection is the infection that has been caught in a hospital and is potentially caused by organisms that are not susceptible to antibiotics. Nosocomial infections are transmitted directly or indirectly through air and may cause different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58c70b9e35e2f0a732a6616ecc944619
https://doaj.org/article/7dfd30bf8161413e8c70590e35985ce2
https://doaj.org/article/7dfd30bf8161413e8c70590e35985ce2