Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Shyamalika Gopalan"'
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/c46d28289421482983e3bf9f44e14ffd
Autor:
Janitza L. Montalvo-Ortiz, Joel Gelernter, Zhongshan Cheng, Matthew J. Girgenti, Ke Xu, Xinyu Zhang, Shyamalika Gopalan, Hang Zhou, Ronald S. Duman, Steven M. Southwick, John H. Krystal, Traumatic Stress Brain Research Study Group, Robert H. Pietrzak
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Posttraumatic stress disorder (PTSD) is a chronic and disabling psychiatric disorder prevalent in military veterans. Epigenetic mechanisms have been implicated in the etiology of PTSD, with DNA methylation being the most studied to identify
Externí odkaz:
https://doaj.org/article/9b03087f9a824d1cb85a96fc7bccecc2
Autor:
Gita A. Pathak, Kritika Singh, Tyne W. Miller-Fleming, Frank R. Wendt, Nava Ehsan, Kangcheng Hou, Ruth Johnson, Zeyun Lu, Shyamalika Gopalan, Loic Yengo, Pejman Mohammadi, Bogdan Pasaniuc, Renato Polimanti, Lea K. Davis, Nicholas Mancuso
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Genome-wide association studies of COVID-19 have identified genetic loci affecting disease severity, but the mechanisms remain to be fully described. Here, the authors use genetically predicted transcriptome, splicing and proteome data to identify po
Externí odkaz:
https://doaj.org/article/a355ee0c16c940cdb2b6a67d3d67f2b5
Autor:
Laura R. Botigué, Shiya Song, Amelie Scheu, Shyamalika Gopalan, Amanda L. Pendleton, Matthew Oetjens, Angela M. Taravella, Timo Seregély, Andrea Zeeb-Lanz, Rose-Marie Arbogast, Dean Bobo, Kevin Daly, Martina Unterländer, Joachim Burger, Jeffrey M. Kidd, Krishna R. Veeramah
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
The European continent is thought to have played a major role in the origins of modern dogs. Here, analysing two ancient dog genomes from Germany, the authors find significant genetic continuity throughout the Neolithic period and time dog domesticat
Externí odkaz:
https://doaj.org/article/37b08385a8534eb8a9250a2aa627aa7e
Autor:
Daisy V Zavala, Natali Dzikowski, Shyamalika Gopalan, Karra Harrington, Giancarlo Pasquini, Jacqueline Mogle, Kerry Reid, Martin Sliwinski, Jennifer Graham-Engeland, Christopher Gerald Engeland, Kristin Bernard, Krishna Veeramah, Stacey Scott
DNA methylation-derived epigenetic clocks offer the opportunity to examine aspects of age acceleration (i.e., the difference between an individual’s biological age and chronological age), which vary among individuals and may better account for age-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30adc2abb9a08fb5b3ea9b6153b1c8e7
https://doi.org/10.31234/osf.io/sre8p
https://doi.org/10.31234/osf.io/sre8p
Autor:
Zeyun Lu, Shyamalika Gopalan, Dong Yuan, David V. Conti, Bogdan Pasaniuc, Alexander Gusev, Nicholas Mancuso
Publikováno v:
Am J Hum Genet
Transcriptome-wide association studies (TWAS) are a powerful approach to identify genes whose expression associates with complex disease risk. However, non-causal genes can exhibit association signals due to confounding by linkage disequilibrium patt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94bb842bd9f2dd4fd221a1113a2c2f99
https://europepmc.org/articles/PMC9388396/
https://europepmc.org/articles/PMC9388396/
Publikováno v:
Evolutionary anthropology, vol 30, iss 3
Evolutionary Anthropology
Evolutionary Anthropology
Questions surrounding the timing, extent, and evolutionary consequences of archaic admixture into human populations have a long history in evolutionary anthropology. More recently, advances in human genetics, particularly in the field of ancient DNA,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85df0eead06e0f72295745b6fbcd5f0d
https://doi.org/10.1002/evan.21895
https://doi.org/10.1002/evan.21895
Autor:
Shyamalika Gopalan, Samuel Pattillo Smith, Katharine Korunes, Iman Hamid, Sohini Ramachandran, Amy Goldberg
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences. 377
Over the past 50 years, geneticists have made great strides in understanding how our species' evolutionary history gave rise to current patterns of human genetic diversity classically summarized by Lewontin in his 1972 paper, ‘The Apportionment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b99b962dd1d7523eb76047257c5ee18
https://doi.org/10.1098/rstb.2020.0410
https://doi.org/10.1098/rstb.2020.0410
Autor:
Pejman Mohammadi, Tyne W Miller-Fleming, Renato Polimanti, Nicholas Mancuso, Kangcheng Hou, Lea K. Davis, Loic Yengo, Zeyun Lu, Nava Ehsan, Kritika Singh, Gita A. Pathak, Bogdan Pasaniuc, Ruth Johnson, Frank R. Wendt, Shyamalika Gopalan
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature communications, vol 12, iss 1
Despite rapid progress in characterizing the role of host genetics in SARS-Cov-2 infection, there is limited understanding of genes and pathways that contribute to COVID-19. Here, we integrate a genome-wide association study of COVID-19 hospitalizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::137d0c0c86989e4f5c7861bd7d634ec7
http://europepmc.org/articles/PMC8316582
http://europepmc.org/articles/PMC8316582
Autor:
Frank R. Wendt, Kangcheng Hou, Lea K. Davis, Loic Yengo, Shyamalika Gopalan, Pejman Mohammadi, Kritika Singh, Gita A. Pathak, Bogdan Pasaniuc, Nicholas Mancuso, Ruth Johnson, Tyne W Miller-Fleming, Renato Polimanti, Nava Ehsan, Zeyun Lu
Despite rapid progress in characterizing the role of host genetics in SARS-Cov-2 infection, there is limited understanding of genes and pathways that contribute to COVID-19. Here, we integrated a genome-wide association study of COVID-19 hospitalizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6579d6fc6bf6fd12e6c9554289bd3f8
https://doi.org/10.1101/2020.12.07.20245308
https://doi.org/10.1101/2020.12.07.20245308