Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Shyamalagauri Jadhav"'
Autor:
Ethan Baratz, Olga Protchenko, Shyamalagauri Jadhav, Deliang Zhang, Pierre-Christian Violet, Samantha Grounds, Minoo Shakoury-Elizeh, Mark Levine, Caroline C. Philpott
Publikováno v:
The Journal of Nutrition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9aa7c9642da2b5cde9cf7fd5a0885aaf
https://doi.org/10.1016/j.tjnut.2023.04.018
https://doi.org/10.1016/j.tjnut.2023.04.018
Autor:
Fengmin Li, Yulia Y. Tyurina, Hülya Bayır, Shyamalagauri Jadhav, Vladimir A. Tyurin, James E. Cox, Christopher J. Chang, Oksana Gavrilova, Manik C. Ghosh, Valerian E. Kagan, Ethan Baratz, Caroline C. Philpott, J. Alan Maschek, Allegra T. Aron, Olga Protchenko, Minoo Shakoury-Elizeh
Publikováno v:
Hepatology (Baltimore, Md.), vol 73, iss 3
Hepatology
Hepatology
Background and aims Iron is essential yet also highly chemically reactive and potentially toxic. The mechanisms that allow cells to use iron safely are not clear; defects in iron management are a causative factor in the cell-death pathway known as fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04d1b321f653036d2258f9414d8d4b3
https://doi.org/10.1002/hep.31328
https://doi.org/10.1002/hep.31328
Autor:
Sarju J. Patel, Olga Protchenko, Caroline C. Philpott, Minoo Shakoury-Elizeh, Shyamalagauri Jadhav, Ethan Baratz
Publikováno v:
Proc Natl Acad Sci U S A
Poly(rC)-binding protein (PCBP1) is a multifunctional adaptor protein that can coordinate single-stranded nucleic acids and iron-glutathione complexes, altering the processing and transfer of these ligands through interactions with other proteins. Mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72ae63165fef1bd85ef4e48e944b8237
https://doi.org/10.1073/pnas.2104666118
https://doi.org/10.1073/pnas.2104666118
Autor:
Wenxi Yu, Maik Hüttemann, Shyamalagauri Jadhav, Michael Salsaa, Jenney Liu, Miriam L. Greenberg, Bianca Pereira
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
The widely used mood stabilizer valproate (VPA) causes perturbation of energy metabolism, which is implicated in both the therapeutic mechanism of action of the drug as well as drug toxicity. To gain insight into these mechanisms, we determined the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94eef53bfbd7ac90379484d4cd391016
https://doi.org/10.1038/s41598-020-68725-5
https://doi.org/10.1038/s41598-020-68725-5
Publikováno v:
Journal of Biological Chemistry. 292:4953-4959
Bipolar disorder (BD) is a severe psychiatric illness affecting ∼1% of the world population. Valproate (VPA) and lithium, widely used for the treatment of BD, are not universally effective. These drugs have been shown to cause inositol depletion, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c149728b142fa8287a0289f4662eaf
https://doi.org/10.1074/jbc.m117.775460
https://doi.org/10.1074/jbc.m117.775460
Autor:
Andrey V. Kozlov, Shyamalagauri Jadhav, Anna A. Shvedova, Yury A. Vladimirov, Olga Protchenko, Y.Y. Tyurina, Indira H. Shrivastava, Sergey Bolevich, Detcho A. Stoyanovsky, Hülya Bayır, Valerian E. Kagan, Caroline C. Philpott, Vladimir A. Tyurin, Ivet Bahar
Duality of iron as an essential cofactor of many enzymatic metabolic processes and as a catalyst of poorly controlled redox-cycling reactions defines its possible biological beneficial and hazardous role in the body. In this review, we discuss these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a46f72fb9c06caa9c18284314627482
https://europepmc.org/articles/PMC6555767/
https://europepmc.org/articles/PMC6555767/
Publikováno v:
Free radical biologymedicine. 133
Mammalian cells contain thousands of metalloproteins and have evolved sophisticated systems for ensuring that metal cofactors are correctly assembled and delivered to their proper destinations. Equally critical in this process are the strategies to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3911c177fe7110e6c9eaee812846a413
https://pubmed.ncbi.nlm.nih.gov/30321701
https://pubmed.ncbi.nlm.nih.gov/30321701
Publikováno v:
Clinical Lipidology. 9:533-551
The development of therapies for neuropsychiatric disorders is hampered by the lack of understanding of the mechanisms underlying their pathologies. While aberrant sphingolipid metabolism is associated with psychiatric illness, the role of sphingolip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a0d887b1861d7e110c1a30f69f60aa6
https://doi.org/10.2217/clp.14.47
https://doi.org/10.2217/clp.14.47
Autor:
Sarah Brice Russo, Stéphanie Cottier, Shyamalagauri Jadhav, Miriam L. Greenberg, L. Ashley Cowart, Roger Schneiter
Bipolar disorder (BD), which is characterized by depression and mania, affects 1–2% of the world population. Current treatments are effective in only 40–60% of cases and cause severe side effects. Valproate (VPA) is one of the most widely used dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd8e933cbafa9459c96220de0aa7fcb
https://europepmc.org/articles/PMC5064004/
https://europepmc.org/articles/PMC5064004/