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pro vyhledávání: '"Shyamal Parekh"'
Autor:
Michael G. Fickes, Zhenping Tian, Shyamal Parekh, Todd S. Mcdermott, Sou-Jen Chang, Steven J. Wittenberger, Ashok K. Gupta, Dilinie P. Fernando, David R. Hill
Publikováno v:
Organic Process Research & Development. 6:329-335
A process for the preparation of matrix metalloproteinase inhibitor ABT-518 has been developed. Significant improvements have been made to the first generation synthesis and are described here. The new process is very robust and efficient; multikilog