Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Shyamal Mosalaganti"'
Autor:
Renaldo Sutanto, Shyamal Mosalaganti
Publikováno v:
ACS Central Science, Vol 10, Iss 8, Pp 1439-1441 (2024)
Externí odkaz:
https://doaj.org/article/b09c7bde80f942aa9102eccf05332320
Publikováno v:
eLife, Vol 13 (2024)
Degradation of heparan sulfate (HS), a glycosaminoglycan (GAG) comprised of repeating units of N-acetylglucosamine and glucuronic acid, begins in the cytosol and is completed in the lysosomes. Acetylation of the terminal non-reducing amino group of
Externí odkaz:
https://doaj.org/article/0175b96fff5646088d1d7f89f04807ff
Autor:
Beata Turoňová, Wim J. H. Hagen, Martin Obr, Shyamal Mosalaganti, J. Wouter Beugelink, Christian E. Zimmerli, Hans-Georg Kräusslich, Martin Beck
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Here the authors systematically benchmark cryo-electron tomography acquisition schemes to optimize the attainable resolution for subtomogram averaging, and find that dose-symmetric acquisition with even angular sampling provides a better outcome than
Externí odkaz:
https://doaj.org/article/dc1b4bdb76a14aba9eff82a68c42333e
Autor:
Shyamal Mosalaganti, Jan Kosinski, Sahradha Albert, Miroslava Schaffer, Daniela Strenkert, Patrice A. Salomé, Sabeeha S. Merchant, Jürgen M. Plitzko, Wolfgang Baumeister, Benjamin D. Engel, Martin Beck
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
While the architecture of vertebrate nuclear pore complexes (NPCs) is well understood, the extent of its evolutionary conservation is still unclear. Here, the authors analyze the in situ architecture of an algal NPC, revealing distinct structural fea
Externí odkaz:
https://doaj.org/article/d5b2c6bf446f4dc1bf1a94753ef03049
Autor:
Yahui Liu, Arsen Petrovic, Pascaline Rombaut, Shyamal Mosalaganti, Jenny Keller, Stefan Raunser, Franz Herzog, Andrea Musacchio
Publikováno v:
Open Biology, Vol 6, Iss 2 (2016)
Accurate chromosome segregation during mitosis and meiosis is crucial for cellular and organismal viability. Kinetochores connect chromosomes with spindle microtubules and are essential for chromosome segregation. These large protein scaffolds emerge
Externí odkaz:
https://doaj.org/article/6f66427b25e24b628376f360fa257d59
Autor:
Martin Beck, Moritz Kueblbeck, Vilma Jimenez Sabinina, Jean-Karim Hériché, Shyamal Mosalaganti, Jonas Ries, Jan Ellenberg, Andrea Callegari, Anna Szymborska, Philipp Hoess, Bianca Nijmeijer, M. Julius Hossain
Publikováno v:
Molecular Biology of the Cell
Nuclear pore complexes (NPCs) are large macromolecular machines that mediate the traffic between the nucleus and the cytoplasm. In vertebrates, each NPC consists of ∼1000 proteins, termed nucleoporins, and has a mass of more than 100 MDa. While a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696f818f8eeb6235a5566e7e6c839bcc
https://doi.org/10.1091/mbc.e20-11-0728
https://doi.org/10.1091/mbc.e20-11-0728
Autor:
Pranav N.M. Shah, James B. Gilchrist, Björn O. Forsberg, Alister Burt, Andrew Howe, Shyamal Mosalaganti, William Wan, Julika Radecke, Yuriy Chaban, Geoff Sutton, David I. Stuart, Mark Boyce
Publikováno v:
Cell Host & Microbe. 31:604-615.e4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adc7befdec20e0e6a58655db07b163c1
https://doi.org/10.1016/j.chom.2023.03.004
https://doi.org/10.1016/j.chom.2023.03.004
Autor:
Sören von Bülow, Michael D. Mühlebach, Andre Schwarz, Sonja Welsch, Nayara Trevisan Doimo de Azevedo, Ger van Zandbergen, Florian Blanc, Shyamal Mosalaganti, Jonathan J M Landry, Katrin Bagola, Martin Beck, Wim J. H. Hagen, Mateusz Sikora, Christoph Schürmann, Cindy Hörner, Roberto Covino, Michael Gecht, Jacomine Krijnse Locker, Gerhard Hummer, Beata Turoňová
Publikováno v:
Science (New York, N.y.)
Science
Signal Transduction and Targeted Therapy
Science
Signal Transduction and Targeted Therapy
Flexible spikes The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein enables viral entry into host cells by binding to the angiotensin-converting enzyme 2 (ACE2) receptor and is a major target for neutralizing antibodies. Ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17e99d8ec34fe4c8a891914b0da32c3e
http://europepmc.org/articles/PMC7665311
http://europepmc.org/articles/PMC7665311
Autor:
Eungjin Ahn, Byungchul Kim, Soyoung Park, Amanda L. Erwin, Suk Hyun Sung, Robert Hovden, Shyamal Mosalaganti, Uhn-Soo Cho
Cryogenic electron microscopy (cryo-EM) has become a widely used tool for determining protein structure. Despite recent technology advances, sample preparation remains a major bottleneck for several reasons, including protein denaturation at the air/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a698019009746c6845b94dfa884579ca
https://doi.org/10.1101/2021.12.26.474209
https://doi.org/10.1101/2021.12.26.474209
Autor:
Beata Turonova, Martin Beck, Florian Schmidt, Marc Siggel, Katarzyna Buczak, Agnieszka Obarska-Kosinska, Shyamal Mosalaganti, Gerhard Hummer, Christian E. Zimmerli, Wim J. H. Hagen, Erica Margiotta, Jan Kosinski, Marie-Therese Mackmull
Nuclear pore complexes (NPCs) mediate nucleocytoplasmic transport. Their intricate 120 MDa architecture remains incompletely understood. Here, we report a near-complete structural model of the human NPC scaffold with explicit membrane and in multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74c67cf01cff9d23a20fcf1334cd233a
https://doi.org/10.1101/2021.10.26.465776
https://doi.org/10.1101/2021.10.26.465776