Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Shyamal A. Mehta"'
Autor:
Sophie E. Mastenbroek, Jacob W. Vogel, Lyduine E. Collij, Geidy E. Serrano, Cécilia Tremblay, Alexandra L. Young, Richard A. Arce, Holly A. Shill, Erika D. Driver-Dunckley, Shyamal H. Mehta, Christine M. Belden, Alireza Atri, Parichita Choudhury, Frederik Barkhof, Charles H. Adler, Rik Ossenkoppele, Thomas G. Beach, Oskar Hansson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Lewy body (LB) diseases, characterized by the aggregation of misfolded α-synuclein proteins, exhibit notable clinical heterogeneity. This may be due to variations in accumulation patterns of LB neuropathology. Here we apply a data-driven di
Externí odkaz:
https://doaj.org/article/8ead8da20952462faeaafda287e2a07f
Autor:
Cécilia Tremblay, Geidy E. Serrano, Nathaniel Dunckley, Nan Zhang, Kimberly L. Fiock, Charles H. Adler, Erika Driver-Dunckley, Shyamal H. Mehta, Holly A. Shill, Thomas G. Beach
Publikováno v:
Journal of Parkinson's Disease. 13:333-340
Background: Essential tremor (ET) is a common movement disorder in which cerebellar microscopic and volume alterations have been repeatedly reported although with disagreement between studies. However, pronounced heterogeneity was found with regard t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0e118a0ce433ec6ca6a546817592e63
https://doi.org/10.3233/jpd-225033
https://doi.org/10.3233/jpd-225033
Autor:
Erika D Driver-Dunckley, Nan Zhang, Geidy E Serrano, Nathaniel A Dunckley, Lucia I Sue, Holly A Shill, Shyamal H Mehta, Christine Belden, Cecilia Tremblay, Alireza Atri, Charles H Adler, Thomas G Beach
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 82:438-451
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ebded8dbc1e0a13f02e5d97c878586a
https://doi.org/10.1093/jnen/nlad025
https://doi.org/10.1093/jnen/nlad025
Autor:
Thomas G Beach, Lucia I Sue, Sarah Scott, Anthony J Intorcia, Jessica E Walker, Richard A Arce, Michael J Glass, Claryssa I Borja, Madison P Cline, Spencer J Hemmingsen, Sanaria Qiji, Analisa Stewart, Kayleigh N Martinez, Addison Krupp, Rylee McHattie, Monica Mariner, Ileana Lorenzini, Angela Kuramoto, Kathy E Long, Cécilia Tremblay, Richard J Caselli, Bryan K Woodruff, Steven Z Rapscak, Christine M Belden, Danielle Goldfarb, Parichita Choudhury, Erika D Driver-Dunckley, Shyamal H Mehta, Marwan N Sabbagh, Holly A Shill, Alireza Atri, Charles H Adler, Geidy E Serrano
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 82:457-466
Cerebral white matter rarefaction (CWMR) was considered by Binswanger and Alzheimer to be due to cerebral arteriolosclerosis. Renewed attention came with CT and MR brain imaging, and neuropathological studies finding a high rate of CWMR in Alzheimer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc7a948f73150d9128a670c619f96e0e
https://doi.org/10.1093/jnen/nlad026
https://doi.org/10.1093/jnen/nlad026
Autor:
Sana, Aslam, Nan, Zhang, Charles H, Adler, Thomas G, Beach, Erika, Driver-Dunckley, Shyamal H, Mehta, Holly, Shill
Publikováno v:
Neurol Clin Pract
Background and ObjectivesThe aim of this study is to assess clinical and pathologic correlations of jaw tremor in 3 cohorts enrolled in a long-term aging study. Jaw/lip tremor has been described in various movement disorders but the impact of seeing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf638b8821e46970a703afbf82d9761
https://doi.org/10.1212/cpj.0000000000200072
https://doi.org/10.1212/cpj.0000000000200072
Autor:
Cécilia Tremblay, Geidy E Serrano, Anthony J Intorcia, Monica R Mariner, Lucia I Sue, Richard A Arce, Alireza Atri, Charles H Adler, Christine M Belden, Holly A Shill, Erika Driver-Dunckley, Shyamal H Mehta, Thomas G Beach
Publikováno v:
J Neuropathol Exp Neurol
The Alzheimer disease (AD) neuropathological hallmarks amyloid β (Aβ) and tau neurofibrillary (NF) pathology have been reported in the olfactory bulb (OB) in aging and in different neurodegenerative diseases, which coincides with frequently reporte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef15489344773de15f32a6e299b2683
https://doi.org/10.1093/jnen/nlac042
https://doi.org/10.1093/jnen/nlac042
Autor:
Michael Malek-Ahmadi, Thomas G Beach, Edward Zamrini, Charles H Adler, Marwan N Sabbagh, Holly A Shill, Sandra A Jacobson, Christine M Belden, Richard J Caselli, Brian K Woodruff, Steven Z Rapscak, Geoffrey L Ahern, Jiong Shi, John N Caviness, Erika Driver-Dunckley, Shyamal H Mehta, David R Shprecher, Bryan M Spann, Pierre Tariot, Kathryn J Davis, Kathy E Long, Lisa R Nicholson, Anthony Intorcia, Michael J Glass, Jessica E Walker, Michael Callan, Jasmine Curry, Brett Cutler, Javon Oliver, Richard Arce, Douglas G Walker, Lih-Fen Lue, Geidy E Serrano, Lucia I Sue, Kewei Chen, Eric M Reiman
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0217566 (2019)
BackgroundNeuropathology has demonstrated a high rate of comorbid pathology in dementia due to Alzheimer's disease (ADD). The most common major comorbidity is Lewy body disease (LBD), either as dementia with Lewy bodies (AD-DLB) or Alzheimer's diseas
Externí odkaz:
https://doaj.org/article/20865cfb54d54fcb81882a55f80987e8
Autor:
Marcus N, Callister, Cynthia B, Stonnington, Andrea, Cuc, Sally B, Alcott, Erika D, Driver-Dunckley, Shyamal H, Mehta, Shemonti, Hasan, Lisa A, Marks, Dean M, Wingerchuk, Cumara B, O'Carroll
Publikováno v:
The Neurologist. 27:82-88
Functional movement disorders (FMD, aka psychogenic movement disorders) are very common and frequently chronic and disabling. Despite this, there is a paucity of evidence-based treatment to manage and alleviate these conditions. Specialized physical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::441d81985a0b8bfe772cb4ab6f9121ef
https://doi.org/10.1097/nrl.0000000000000408
https://doi.org/10.1097/nrl.0000000000000408
Autor:
Geidy E. Serrano, Thomas G. Beach, Michael J. Glass, Shyamal H. Mehta, Lucia I. Sue, Jessica E. Walker, Richard Arce, Charles H. Adler, Anthony Intorcia, Holly A. Shill, Erika Driver-Dunckley, Courtney M. Nelson
Publikováno v:
J Parkinsons Dis
Background: Braak and others have proposed that Lewy-type α-synucleinopathy in Parkinson’s disease (PD) may arise from an exogenous pathogen that passes across the gastric mucosa and then is retrogradely transported up the vagus nerve to the medul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7b2367c1db868cec5fb263f2d4becf
https://doi.org/10.3233/jpd-212733
https://doi.org/10.3233/jpd-212733
Autor:
Geidy E Serrano, Jessica E Walker, Cécilia Tremblay, Ignazio S Piras, Matthew J Huentelman, Christine M Belden, Danielle Goldfarb, David Shprecher, Alireza Atri, Charles H Adler, Holly A Shill, Erika Driver-Dunckley, Shyamal H Mehta, Richard Caselli, Bryan K Woodruff, Chadwick F Haarer, Thomas Ruhlen, Maria Torres, Steve Nguyen, Dasan Schmitt, Steven Z Rapscak, Christian Bime, Joseph L Peters, Ellie Alevritis, Richard A Arce, Michael J Glass, Daisy Vargas, Lucia I Sue, Anthony J Intorcia, Courtney M Nelson, Javon Oliver, Aryck Russell, Katsuko E Suszczewicz, Claryssa I Borja, Madison P Cline, Spencer J Hemmingsen, Sanaria Qiji, Holly M Hobgood, Joseph P Mizgerd, Malaya K Sahoo, Haiyu Zhang, Daniel Solis, Thomas J Montine, Gerald J Berry, Eric M Reiman, Katharina Röltgen, Scott D Boyd, Benjamin A Pinsky, James L Zehnder, Pierre Talbot, Marc Desforges, Michael DeTure, Dennis W Dickson, Thomas G Beach
Publikováno v:
Journal of neuropathology and experimental neurology. 81(9)
Brains of 42 COVID-19 decedents and 107 non-COVID-19 controls were studied. RT-PCR screening of 16 regions from 20 COVID-19 autopsies found SARS-CoV-2 E gene viral sequences in 7 regions (2.5% of 320 samples), concentrated in 4/20 subjects (20%). Add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f50b643fd8ecbfa058adeefedc9c38
https://pubmed.ncbi.nlm.nih.gov/35818336
https://pubmed.ncbi.nlm.nih.gov/35818336