Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Shyam S. Chauhan"'
Publikováno v:
Annals of the National Academy of Medical Sciences (India), Vol 57, Iss 02, Pp 108-116 (2021)
Cysteine cathepsins are lysosomal proteases that require Cys-His ion pair in their catalytic site for enzymatic activity. While their aberrant expression and oncogenic functions have been widely reported in solid tumors, recent findings suggest that
Externí odkaz:
https://doaj.org/article/8f09818c26ce49e6897c886aba6a4e16
Autor:
Ajaz A. Bhat, Parvaiz Yousuf, Nissar A. Wani, Arshi Rizwan, Shyam S. Chauhan, Mushtaq A. Siddiqi, Davide Bedognetti, Wael El-Rifai, Michael P. Frenneaux, Surinder K. Batra, Mohammad Haris, Muzafar A. Macha
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-15 (2021)
Abstract Head and neck squamous cell carcinoma (HNSCC) is a very aggressive disease with a poor prognosis for advanced-stage tumors. Recent clinical, genomic, and cellular studies have revealed the highly heterogeneous and immunosuppressive nature of
Externí odkaz:
https://doaj.org/article/2045bd459b934f1196c31d61fd53e439
Autor:
Sarita Kumari, Mohit Arora, Jay Singh, Lokesh K. Kadian, Rajni Yadav, Shyam S. Chauhan, Anita Chopra
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Hepatocellular carcinoma (HCC) is an aggressive gastrointestinal malignancy with a high rate of mortality. Multiple studies have individually recognized members of RAP gene family as critical regulators of tumor progression in several cancers, includ
Externí odkaz:
https://doaj.org/article/5b52bb84e7c548eaa46501cfd1efdfd2
Autor:
Vikas Kumar, Moien Rasheed Lone, Anurag Kumar, Vinnyfred Vincent, Himani Thakkar, Deepika Mishra, Shyam S. Chauhan
Publikováno v:
Diagnostics, Vol 12, Iss 6, p 1332 (2022)
The heterogeneous nuclear ribonucleoprotein D (hnRNPD) serves as a prognostic marker for oral squamous cell carcinoma (OSCC). We evaluated the diagnostic potential of hnRNPD to differentiate between OSCC and normal mucosa. Immunohistochemistry for hn
Externí odkaz:
https://doaj.org/article/aa860b894dbf4c89baa1749fa79c97fb
Autor:
Jay Singh, Sarita Kumari, Mohit Arora, Deepak Verma, Jayanth Kumar Palanichamy, Rajive Kumar, Gunjan Sharma, Sameer Bakhshi, Deepam Pushpam, M. Shadab Ali, Amar Ranjan, Pranay Tanwar, Shyam S. Chauhan, Archna Singh, Anita Chopra
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Glucocorticoid (GC), such as prednisolone, is an essential component of multidrug chemotherapy regimen for pediatric acute lymphoblastic leukemia (ALL). Resistance to GC in leukemia cells is associated with disease progression and poor prognosis. Des
Externí odkaz:
https://doaj.org/article/9b97ed2f6b2a4a5bafb9ebde70955ea6
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Melanoma associated antigen (MAGE) is an extensively studied family of tumor-associated genes that share a common MAGE homology domain (MHD). Based upon their expression pattern, MAGE genes have been broadly classified into type 1 MAGEs (T1Ms) and ty
Externí odkaz:
https://doaj.org/article/337c447af4384f9ba492687dde436a06
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Classical Non-homologous End Joining (NHEJ) pathway is the mainstay of cellular response to DNA double strand breaks. While aberrant expression of genes involved in this pathway has been linked with genomic instability and drug resistance in several
Externí odkaz:
https://doaj.org/article/e67150341d4f42f6a4d352022e5a5ff9
Autor:
Siddharth Mehra, Rajesh Panwar, Bhaskar Thakur, Rajni Yadav, Manish Kumar, Ratnakar Singh, Nihar Ranjan Dash, Peush Sahni, Shyam S. Chauhan
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Background: Gallbladder carcinoma (GBC) exhibits poor prognosis due to its detection at an advanced stage. Upregulation of lysosomal cysteine proteases cathepsin L (CTSL) and cathepsin B (CTSB) has been implicated in several tumorigenic processes. Ho
Externí odkaz:
https://doaj.org/article/f7d6670ccd844400a4e812de39355634
Autor:
Ajaz A. Bhat, Parvaiz Yousuf, Nissar A. Wani, Arshi Rizwan, Shyam S. Chauhan, Mushtaq A. Siddiqi, Davide Bedognetti, Wael El-Rifai, Michael P. Frenneaux, Surinder K. Batra, Mohammad Haris, Muzafar A. Macha
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41392-021-00503-9
Externí odkaz:
https://doaj.org/article/0df66f68dbcb416b8fe87cbfe9ad9faa
Autor:
Siddharth Mehra, Manish Kumar, Ratnakar Singh, Bhaskar Thakur, Rajiv Narang, Shyam S. Chauhan
Publikováno v:
Indian Heart Journal, Vol 67, Iss S1, Pp S106-S107 (2015)
Externí odkaz:
https://doaj.org/article/fe835bc1b33541a9b7b33383a28c71ae